4551508
LRP/MVP (Major Vault Protein) Ab-2 Mouse Monoclonal Antibody, Epredia™
Recommended for a variety of techniques, Epredia™ LRP/MVP (Major Vault Protein) Ab-2, Mouse Monoclonal Antibody provides accurate, reproducible results.
Manufacturer: Fischer Scientific
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Antigen
LRP/MVP (Major Vault Protein) Ab-2
Applications
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Host Species
Mouse
Research Discipline
Cancer and Tumor Biology
Immunogen
Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells
Primary or Secondary
Primary
Clone
1032
Classification
Monoclonal
Regulatory Status
RUO
Target Species
Human, Rat
Isotype
IgG2a κ
Related Products
Description
- Major vault protein (MVP) is identical to lung-resistance related protein (LRP)
- Its shape is reminiscent of the nucleopore central plug
- Treatment of cells with estradiol increases the amount of MVP in nuclear extract
- The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate
- Antibodies to progesterone and glucocorticoid receptors are also able to co-immunoprecipitate the MVP
- Reportedly, the lung-resistance related protein (LRP) is identical to human MVP
- LRP is overexpressed in many neoplastic tissues and cell lines indicating a poor response to chemotherapy
- Host Species: Mouse Clone: 1032 Isotype: IgG1/κ Species Reactivity: Human and Rat
- Others not known
- Epitope: Not determined Immunogen: Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells Molecular Weight: 104-110kDa Positive Control: SKBR-3 cells, Breast tumors Cellular Localization: Cytoplasmic Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Immunoprecipitation (Native verified) Gel Supershift Flow Cytometry Note: USA: RUO; Int'l: RUO
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Antigen: LRP/MVP (Major Vault Protein) Ab-2
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Host Species: Mouse
Research Discipline: Cancer and Tumor Biology
Immunogen: Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells
Primary or Secondary: Primary
Clone: 1032
Classification: Monoclonal
Regulatory Status: RUO
Target Species: Human, Rat
Isotype: IgG2a κ
Antigen:
LRP/MVP (Major Vault Protein) Ab-2
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Host Species:
Mouse
Research Discipline:
Cancer and Tumor Biology
Immunogen:
Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells
Primary or Secondary:
Primary
Clone:
1032
Classification:
Monoclonal
Regulatory Status:
RUO
Target Species:
Human, Rat
Isotype:
IgG2a κ
Antigen: __
Applications: __
Host Species: __
Research Discipline: __
Immunogen: __
Primary or Secondary: __
Clone: __
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Regulatory Status:
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Antigen: __
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Antigen: MAP 2a,b (Microtubule-Associated Protein) Ab-2
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Host Species: Mouse
Research Discipline: Neuroscience
Immunogen: Bovine brain microtubule associated protein 2
Primary or Secondary: Primary
Clone: AP20
Classification: Monoclonal
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1
Antigen:
MAP 2a,b (Microtubule-Associated Protein) Ab-2
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Host Species:
Mouse
Research Discipline:
Neuroscience
Immunogen:
Bovine brain microtubule associated protein 2
Primary or Secondary:
Primary
Clone:
AP20
Classification:
Monoclonal
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1