4555631
p53 Ab-8 Mouse Monoclonal Antibody, Epredia™
Deliver accurate, reproducible results with the Epredia™ p53 Ab-8, Mouse Monoclonal Antibody.
Manufacturer: Fischer Scientific
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Antigen
p53 Ab-8
Applications
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate
Unconjugated
Regulatory Status
IVD
Target Species
Human
Isotype
IgG2a, IgG2b
Clone
DO-7 + BP53-12
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Cancer and Tumor Biology
Immunogen
Recombinant human p53 protein
Primary or Secondary
Primary
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Description
- Description p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis
- It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair
- Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma
- Host Species: Mouse Clone: DO-7 + BP53-12 Isotype: IgG2b + IgG2a Species Reactivity: Human
- Others not known
- Epitope: aa 37-45 and aa 20-25 Immunogen: Recombinant human p53 protein Molecular Weight: 53kDa Positive Control: MDA-231, SKBR-3 cells or Colon CA Cellular Localization: Nuclear Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Immunoprecipitation (Native and denatured)
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Antigen: p53 Ab-8
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Regulatory Status: IVD
Target Species: Human
Isotype: IgG2a, IgG2b
Clone: DO-7 + BP53-12
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cancer and Tumor Biology
Immunogen: Recombinant human p53 protein
Primary or Secondary: Primary
Antigen:
p53 Ab-8
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Regulatory Status:
IVD
Target Species:
Human
Isotype:
IgG2a, IgG2b
Clone:
DO-7 + BP53-12
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cancer and Tumor Biology
Immunogen:
Recombinant human p53 protein
Primary or Secondary:
Primary
Antigen: p53
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: IVD
Target Species: __
Isotype: __
Clone: SP5
Classification: Monoclonal
Host Species: Rabbit
Research Discipline: Cancer and Tumor Biology
Immunogen: Recombinant human full-length wild type p53 protein
Primary or Secondary: Primary
Antigen:
p53
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
IVD
Target Species:
__
Isotype:
__
Clone:
SP5
Classification:
Monoclonal
Host Species:
Rabbit
Research Discipline:
Cancer and Tumor Biology
Immunogen:
Recombinant human full-length wild type p53 protein
Primary or Secondary:
Primary
Antigen: __
Applications: __
Conjugate: __
Regulatory Status: __
Target Species: __
Isotype: __
Clone: __
Classification: __
Host Species: __
Research Discipline: __
Immunogen: __
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Applications:
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Conjugate:
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Regulatory Status:
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Isotype:
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Clone:
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Classification:
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Immunogen:
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Antigen: __
Applications: __
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Regulatory Status: __
Target Species: __
Isotype: __
Clone: __
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