4561936
Synuclein Ab-2 Mouse Monoclonal Antibody, Epredia™
Provide accurate, reproducible results Epredia™ Synuclein Ab-2, Mouse Monoclonal Antibody.
Manufacturer: Fischer Scientific
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Antigen
Synuclein Ab-2
Applications
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate
Unconjugated
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1
Clone
syn211
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Neuroscience
Immunogen
Human recombinant alpha-synuclein
Primary or Secondary
Primary
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Description
- Synnuclein family of proteins is abundantly expressed in neuronal cytosol and presynaptic terminals
- In vertebrates they are encoded by three different genes
- Synucleins have been specifically implemented in three major diseases: Alzheimer's (AD), Parkinson's (PD) and breast cancer
- In AD, a peptide derived from α-synuclein forms an intrinsic component of plaque amyloid
- In PD, an alpha synuclein accumulates in Lewy bodies
- An allele of α synuclein has been linked to many familial cases of PD
- In breast cancer increased expression of γ synuclein correlates with the disease progression
- Synucleins appear to be involved in the membrane plasticity in developing song control system of songbirds
- Host Species: Mouse Clone: syn211 Isotype: IgG1 Species Reactivity: Human
- Does not react with mouse and rat
- Others not known
- Epitope: Not determined Immunogen: Human recombinant α-synuclein Molecular Weight: ∽14kDa Positive Control: Brain Cellular Localization: Neuronal cytosol and presynaptic terminals Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Immunoprecipitation Note: USA: RUO; Int'l: RUO
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Antigen: Synuclein Ab-2
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1
Clone: syn211
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Neuroscience
Immunogen: Human recombinant alpha-synuclein
Primary or Secondary: Primary
Antigen:
Synuclein Ab-2
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1
Clone:
syn211
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Neuroscience
Immunogen:
Human recombinant alpha-synuclein
Primary or Secondary:
Primary
Antigen: __
Applications: __
Conjugate: __
Regulatory Status: __
Target Species: __
Isotype: __
Clone: __
Classification: __
Host Species: __
Research Discipline: __
Immunogen: __
Primary or Secondary: __
Antigen:
__
Applications:
__
Conjugate:
__
Regulatory Status:
__
Target Species:
__
Isotype:
__
Clone:
__
Classification:
__
Host Species:
__
Research Discipline:
__
Immunogen:
__
Primary or Secondary:
__
Antigen: Tartrate Resistant Acid Phosphatase (TRAP) Ab-1
Applications: Immunohistochemistry (Paraffin)
Conjugate: Unconjugated
Regulatory Status: IVD
Target Species: Human
Isotype: IgG2b
Clone: 26E5
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cancer and Tumor Biology
Immunogen: Recombinant protein corresponding to N-terminal region of human TRAP
Primary or Secondary: Primary
Antigen:
Tartrate Resistant Acid Phosphatase (TRAP) Ab-1
Applications:
Immunohistochemistry (Paraffin)
Conjugate:
Unconjugated
Regulatory Status:
IVD
Target Species:
Human
Isotype:
IgG2b
Clone:
26E5
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cancer and Tumor Biology
Immunogen:
Recombinant protein corresponding to N-terminal region of human TRAP
Primary or Secondary:
Primary
Antigen: TdT/Terminal Deoxyribonucleotidyl Transferase Ab-1
Applications: Immunohistochemistry (Paraffin)
Conjugate: Unconjugated
Regulatory Status: IVD
Target Species: __
Isotype: __
Clone: SEN28
Classification: Monoclonal
Host Species: Mouse
Research Discipline: DNA Repair
Immunogen: Recombinant protein corresponding to the amino terminal region of the TdT molecule
Primary or Secondary: Primary
Antigen:
TdT/Terminal Deoxyribonucleotidyl Transferase Ab-1
Applications:
Immunohistochemistry (Paraffin)
Conjugate:
Unconjugated
Regulatory Status:
IVD
Target Species:
__
Isotype:
__
Clone:
SEN28
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
DNA Repair
Immunogen:
Recombinant protein corresponding to the amino terminal region of the TdT molecule
Primary or Secondary:
Primary