4559182

Epredia™ Lab Vision™ Vinculin Ab-1 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Provide accurate, reproducible results with the Epredia™ Vinculin Ab-1, Mouse Monoclonal Antibody.

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Vinculin Ab-1

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Regulatory Status

RUO

Target Species

Human

Isotype

IgG

Clone

VLN01

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Cytoskeletal Protein

Immunogen

Semi-purified vinculin

Primary or Secondary

Primary

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Description

  • Vinculin is an attachment protein involved in the indirect binding of intracellular actin filaments to extracellular fibronectin
  • Vinculin binds to actin capping protein and α actinin, which in turn binds to actin
  • The binding of fibronectin is also indirect where vinculin binds to talin, which in turn binds to the intracellular domain of the fibronectin receptor which itself is the ligand for fibronectin
  • Vinculin is widely distributed in tissue and is expressed where smooth muscle actin and fibroblasts attach to the extracellular matrix
  • Host Species: Mouse Clone: VLN01 Isotype: IgG Species Reactivity: Human
  • Others not known
  • Epitope: Not determined Immunogen: Semi-purified vinculin Molecular Weight: 130kDa (vinculin) and 150kDa (meta-vinculin) Positive Control: HeLa cells, skin Cellular Localization: Cell membrane and cytoplasmic Ab-1 is useful for studies of vinculin in platelet activation
  • Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Immunofluorescence Immunoprecipitation (Denatured verified) Note: USA: RUO; Int'l: RUO

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Antigen:
Vinculin Ab-1

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG

Clone:
VLN01

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cytoskeletal Protein

Immunogen:
Semi-purified vinculin

Primary or Secondary:
Primary

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Antigen:
Prohibitin (Mitochondrial Marker) Ab-1

Applications:
__

Conjugate:
__

Regulatory Status:
RUO

Target Species:
Chicken, Human, Mouse, Porcine, Rat

Isotype:
IgG1

Clone:
II-14-10

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Apoptosis

Immunogen:
Purified recombinant rat prohibitin protein

Primary or Secondary:
Primary

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Antigen:
Prostate Specific Antigen (PSA)

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Regulatory Status:
ASR

Target Species:
__

Isotype:
__

Clone:
EP1588Y

Classification:
Monoclonal

Host Species:
Rabbit

Research Discipline:
Cancer and Tumor Biology

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A synthetic peptide corresponding to residues near the C-terminus of human PSA

Primary or Secondary:
Primary

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Antigen:
Progesterone Receptor Ab-6

Applications:
Immunofluorescence, Immunoprecipitation

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Bovine, Chicken, Human, Rabbit

Isotype:
IgG2b

Clone:
hPRa 6

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cancer and Tumor Biology

Immunogen:
Partially purified PgR from a human endometrial carcinoma (EnCa 101) grown in athymic mice

Primary or Secondary:
Primary