4555622
p21 WAF1 Ab-11 Mouse Monoclonal Antibody, Epredia™
Ensure accurate, reproducible results with the Epredia™ p21WAF1Ab-11, Mouse Monoclonal Antibody.
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
p21superscriptWAF1superscript Ab-11
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Form
Concentrated
Regulatory Status
RUO
Target Species
Human, Rat
Isotype
IgG2b
Clone
CP74
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Cell Cycle
Immunogen
Full length human recombinant p21 protein
Primary or Secondary
Primary
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Description
- Description p21 WAF1 /Cip1/Sdi1/Pic1 is a tumor suppressor protein
- Expression of p21 WAF1 is induced by wild type, but not mutant, p53 suppressor protein
- The p21 WAF1 protein binds to cyclin/CDK complexes and inhibits their kinase activity thereby stopping cell cycle progression
- It also binds to PCNA (proliferating cell nuclear antigen) and blocks DNA replication but not the DNA repair process
- Host Species: Mouse Clone: CP74 Isotype: IgG2b Species Reactivity: Human and Rat
- Others not known
- Epitope: aa 1-80 Immunogen: Full-length human recombinant p21 protein Molecular Weight: 21kDa Positive Control: Raji, PC12 cells Cellular Localization: Nuclear Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Immunoprecipitation (Native verified) Flow Cytometry Note: USA: RUO; Int'l: RUO
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Antigen: p21superscriptWAF1superscript Ab-11
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Form: Concentrated
Regulatory Status: RUO
Target Species: Human, Rat
Isotype: IgG2b
Clone: CP74
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Cycle
Immunogen: Full length human recombinant p21 protein
Primary or Secondary: Primary
Antigen:
p21superscriptWAF1superscript Ab-11
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Form:
Concentrated
Regulatory Status:
RUO
Target Species:
Human, Rat
Isotype:
IgG2b
Clone:
CP74
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Cycle
Immunogen:
Full length human recombinant p21 protein
Primary or Secondary:
Primary
Antigen: p21WAF1 Ab-6
Applications: Immunofluorescence, Western Blot
Form: Concentrated
Regulatory Status: RUO
Target Species: Human, Rat
Isotype: IgG1
Clone: HJ21; same as WA-1
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cancer and Tumor Biology
Immunogen: Human recombinant p21 protein
Primary or Secondary: Primary
Antigen:
p21WAF1 Ab-6
Applications:
Immunofluorescence, Western Blot
Form:
Concentrated
Regulatory Status:
RUO
Target Species:
Human, Rat
Isotype:
IgG1
Clone:
HJ21; same as WA-1
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cancer and Tumor Biology
Immunogen:
Human recombinant p21 protein
Primary or Secondary:
Primary
Antigen: p300/CBP (CREB-Binding Protein) Ab-1
Applications: Immunofluorescence, Immunohistochemistry (Paraffin)
Form: __
Regulatory Status: RUO
Target Species: Human, Mink, Mouse, Non-human Primate, Rat
Isotype: IgG2b κ
Clone: NM11
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Transcription Regulation
Immunogen: E1A affinity purified p300 protein
Primary or Secondary: Primary
Antigen:
p300/CBP (CREB-Binding Protein) Ab-1
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)
Form:
__
Regulatory Status:
RUO
Target Species:
Human, Mink, Mouse, Non-human Primate, Rat
Isotype:
IgG2b κ
Clone:
NM11
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Transcription Regulation
Immunogen:
E1A affinity purified p300 protein
Primary or Secondary:
Primary
Antigen: p53 Ab-8
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Form: __
Regulatory Status: IVD
Target Species: Human
Isotype: IgG2a, IgG2b
Clone: DO-7 + BP53-12
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cancer and Tumor Biology
Immunogen: Recombinant human p53 protein
Primary or Secondary: Primary
Antigen:
p53 Ab-8
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Form:
__
Regulatory Status:
IVD
Target Species:
Human
Isotype:
IgG2a, IgG2b
Clone:
DO-7 + BP53-12
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cancer and Tumor Biology
Immunogen:
Recombinant human p53 protein
Primary or Secondary:
Primary