4555624

p21WAF1 Ab-6 Mouse Monoclonal Antibody, Epredia™

Achieve accurate, reproducible results with the Epredia™ p21WAF1Ab-6, Mouse Monoclonal Antibody.

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

p21WAF1 Ab-6

Applications

Immunofluorescence, Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Research Discipline

Cancer and Tumor Biology

Immunogen

Human recombinant p21 protein

Primary or Secondary

Primary

Clone

HJ21; same as WA-1

Classification

Monoclonal

Form

Concentrated

Regulatory Status

RUO

Target Species

Human, Rat

Isotype

IgG1

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Description

  • Description p21 WAF1 /Cip1/Sdi1/Pic1 is a tumor suppressor protein
  • Expression of p21 WAF1 is induced by wild type, but not mutant, p53 suppressor protein
  • The p21 WAF1 protein binds to cyclin/CDK complexes and inhibits their kinase activity thereby stopping cell cycle progression
  • It also binds to PCNA (proliferating cell nuclear antigen) and blocks DNA replication but not the DNA repair process
  • Host Species: Mouse Clone: HJ21; same as WA-1 Isotype: IgG1 Species Reactivity: Human and Rat
  • Others not known
  • Epitope: Not determined Immunogen: Human recombinant p21 protein Molecular Weight: 21kDa Positive Control: PC12, Ls174T or Raji cells Cellular Localization: Nuclear Recommended for: Immunohistochemistry (Not suitable) Western Blotting Immunofluorescence Immunoprecipitation (Not suitable) Flow Cytometry (Not Suitable) Note: USA: RUO; Int'l: RUO

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Antigen:
p21WAF1 Ab-6

Applications:
Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Cancer and Tumor Biology

Immunogen:
Human recombinant p21 protein

Primary or Secondary:
Primary

Clone:
HJ21; same as WA-1

Classification:
Monoclonal

Form:
Concentrated

Regulatory Status:
RUO

Target Species:
Human, Rat

Isotype:
IgG1

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4555626

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Antigen:
p300/CBP (CREB-Binding Protein) Ab-1

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Conjugate:
__

Host Species:
Mouse

Research Discipline:
Transcription Regulation

Immunogen:
E1A affinity purified p300 protein

Primary or Secondary:
Primary

Clone:
NM11

Classification:
Monoclonal

Form:
__

Regulatory Status:
RUO

Target Species:
Human, Mink, Mouse, Non-human Primate, Rat

Isotype:
IgG2b κ

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4555631

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Antigen:
p53 Ab-8

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Cancer and Tumor Biology

Immunogen:
Recombinant human p53 protein

Primary or Secondary:
Primary

Clone:
DO-7 + BP53-12

Classification:
Monoclonal

Form:
__

Regulatory Status:
IVD

Target Species:
Human

Isotype:
IgG2a, IgG2b

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4555632

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Antigen:
p53

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Research Discipline:
Cancer and Tumor Biology

Immunogen:
Recombinant human full-length wild type p53 protein

Primary or Secondary:
Primary

Clone:
SP5

Classification:
Monoclonal

Form:
__

Regulatory Status:
IVD

Target Species:
__

Isotype:
__