4555632

Epredia™ Lab Vision™ p53 Rabbit Monoclonal Antibody (Clone SP5)

Employ part of a comprehensive antibody portfolio with the Epredia™ p53, Rabbit Monoclonal Antibody (Clone SP5). Studies show rabbit monoclonal antibodies are more sensitive and specific than other available markers.

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

p53

Applications

Western Blot

Conjugate

Unconjugated

Regulatory Status

IVD

Immunogen

Recombinant human full-length wild type p53 protein

Clone

SP5

Classification

Monoclonal

Host Species

Rabbit

Research Discipline

Cancer and Tumor Biology

Primary or Secondary

Primary

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Description

  • Description p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis
  • It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair
  • Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma
  • Host Species: Rabbit Clone: SP5 Isotype: IgG Species Reactivity: Human
  • Others not tested
  • Epitope: Not determined Immunogen: Recombinant human full-length wild type p53 protein Molecular Weight: 53kDa Positive Control: MDA-231 cells, Colon CA Cellular Localization: Nuclear Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting

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Antigen:
p53

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
IVD

Immunogen:
Recombinant human full-length wild type p53 protein

Clone:
SP5

Classification:
Monoclonal

Host Species:
Rabbit

Research Discipline:
Cancer and Tumor Biology

Primary or Secondary:
Primary

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Classification:
__

Host Species:
__

Research Discipline:
__

Primary or Secondary:
__

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Conjugate:
__

Regulatory Status:
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Immunogen:
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Classification:
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Host Species:
__

Research Discipline:
__

Primary or Secondary:
__

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4556009

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Antigen:
PAX-5

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Regulatory Status:
IVD

Immunogen:
Synthetic peptide derived from the C-terminus of human Pax-5 protein

Clone:
SP34

Classification:
Monoclonal

Host Species:
Rabbit

Research Discipline:
Cancer and Tumor Biology

Primary or Secondary:
Primary