4556009

Epredia™ Lab Vision™ Pax-5 Rabbit Monoclonal Antibody

Take advantage of part of a comprehensive antibody portfolio with the Epredia™ Pax-5, Rabbit Monoclonal Antibody.

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

PAX-5

Applications

Immunohistochemistry (Paraffin)

Conjugate

Unconjugated

Regulatory Status

IVD

Immunogen

Synthetic peptide derived from the C-terminus of human Pax-5 protein

Clone

SP34

Classification

Monoclonal

Host Species

Rabbit

Research Discipline

Cancer and Tumor Biology

Primary or Secondary

Primary

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Description

  • Description PAX-5 is a B-cell-specific activator protein (BSAP)
  • In the early stages of B cell developmemt, PAX-5 influences the expression of several B-cell-specific genes, such as CD19 and CD20
  • PAX-5 is expressed primarily in pro-, pre-, and mature B cells, but not in plasma cells
  • PAX-5 is expressed in most B-cell malignancies (pre-B and mature B cell lymphomas/leukemias)
  • Over 90% of cases are positive for PAX-5 in Hodgkin's lymphoma, lymphoplasmacytic lymphoma, Merkel cell and small cell carcinoma
  • T-cell lymphomas, myeloma/plasmacytoma and carcinoid tumors are negative for PAX-5
  • Host Species: Rabbit Clone: SP34 Isotype: IgG Species Reactivity: Human
  • Others not tested
  • Immunogen: Synthetic peptide derived from the C-terminus of human PAX-5 protein Molecular Weight: 50kDa Positive Control: Tonsil Cellular Localization: Nuclear Recommended for: Immunohistochemistry (Formalin/paraffin)

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Fischer Scientific

4556009

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Antigen:
PAX-5

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Regulatory Status:
IVD

Immunogen:
Synthetic peptide derived from the C-terminus of human Pax-5 protein

Clone:
SP34

Classification:
Monoclonal

Host Species:
Rabbit

Research Discipline:
Cancer and Tumor Biology

Primary or Secondary:
Primary

Img

Fischer Scientific

4556010

Provide accurate, reproducible resu...


Antigen:
PAX-5

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
IVD

Immunogen:
Synthetic peptide derived from C-terminus of human Pax-5 protein

Clone:
__

Classification:
Polyclonal

Host Species:
Rabbit

Research Discipline:
B-Cell

Primary or Secondary:
Primary

Img

Fischer Scientific

4556012

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Antigen:
PCNA (Proliferating Cell Nuclear Antigen) Ab-1

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
__

Regulatory Status:
RUO

Immunogen:
Recombinant rat PCNA protein

Clone:
PC10

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Cycle

Primary or Secondary:
Primary

Img

Fischer Scientific

4556012

Provides accurate, reproducible res...


Antigen:
PCNA (Proliferating Cell Nuclear Antigen) Ab-1

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
__

Regulatory Status:
RUO

Immunogen:
Recombinant rat PCNA protein

Clone:
PC10

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Cycle

Primary or Secondary:
Primary