4563344

TIMP-2 Ab-5 Mouse Monoclonal Antibody, Epredia™

Provide accurate, reproducible results with the Epredia™ TIMP-2 Ab-5, Mouse Monoclonal Antibody.

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

TIMP-2 Ab-5

Applications

Immunohistochemistry (Paraffin), Western Blot

Host Species

Mouse

Research Discipline

Proteases And Inhibitors

Immunogen

A synthetic peptide from the N-terminal region of human TIMP-2 protein

Primary or Secondary

Primary

Clone

3A4

Classification

Monoclonal

Regulatory Status

RUO

Target Species

Bovine, Guinea Pig, Human, Mouse, Rabbit, Rat

Isotype

IgG2a κ

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Description

  • TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity
  • TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A)
  • It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B)
  • TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells
  • Host Species: Mouse Clone: 3A4 Isotype: IgG2a/κ Species Reactivity: Human, Mouse, Rat, Rabbit, Cow and Guinea Ppig
  • Others not known
  • Epitope: N-terminal Immunogen: A synthetic peptide from the N-terminal region of human TIMP-2 protein Molecular Weight: 21kDa Positive Control: Conditioned, serum-free medium from (TPA-treated) HFL-1 cells; Pancreatic or colon CA Cellular Localization: Cytoplasmic Recommended for: Immunohistochemistry (Formalin/paraffin only) Western Blotting Immunoprecipitation (Not suitable) Note: USA: RUO; Int'l: RUO

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Antigen:
TIMP-2 Ab-5

Applications:
Immunohistochemistry (Paraffin), Western Blot

Host Species:
Mouse

Research Discipline:
Proteases And Inhibitors

Immunogen:
A synthetic peptide from the N-terminal region of human TIMP-2 protein

Primary or Secondary:
Primary

Clone:
3A4

Classification:
Monoclonal

Regulatory Status:
RUO

Target Species:
Bovine, Guinea Pig, Human, Mouse, Rabbit, Rat

Isotype:
IgG2a κ

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Applications:
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Host Species:
__

Research Discipline:
__

Immunogen:
__

Primary or Secondary:
__

Clone:
__

Classification:
__

Regulatory Status:
__

Target Species:
__

Isotype:
__

Img

Sigma Aldrich

456373

97%...


Antigen:
__

Applications:
__

Host Species:
__

Research Discipline:
__

Immunogen:
__

Primary or Secondary:
__

Clone:
__

Classification:
__

Regulatory Status:
__

Target Species:
__

Isotype:
__

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Fischer Scientific

4563792

Epredia™ Transglutaminase II Ab-1, ...


Antigen:
Transglutaminase II Ab-1

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Host Species:
Mouse

Research Discipline:
Neuroscience

Immunogen:
Purified guinea pig liver TGase II

Primary or Secondary:
Primary

Clone:
CUB 7402

Classification:
Monoclonal

Regulatory Status:
RUO

Target Species:
Canine, Guinea Pig, Human, Rabbit

Isotype:
IgG2a κ