4556437
Epredia™ Lab Vision™ Perforin Ab-2, Mouse Monoclonal Antibody
Employ one marker in a comprehensive antibody portfolio that addresses all major disease states Epredia™ Perforin Ab-2, Mouse Monoclonal Antibody.
Manufacturer: Fischer Scientific
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Antigen
Perforin Ab-2
Applications
Immunohistochemistry (Paraffin)
Conjugate
Unconjugated
Regulatory Status
IVD
Target Species
Human
Isotype
IgG1
Clone
5B10
Classification
Monoclonal
Host Species
Mouse
Research Discipline
T-Cell
Immunogen
Recombinant protein corresponding to C-terminal region of human perforin
Primary or Secondary
Primary
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Description
- Perforin is a potent cytolytic pore-forming protein
- It is a specific marker of functionally active cytotoxic T-lymphocytes (CTLs) and natural killer (NK) cells
- Perforin is a key effector mechanisms in T cell-mediated cytotoxicity
- It mediates cytolysis of target cells by membrane damage and apoptosis
- Host Species: Mouse Clone: 5B10 Isotype: IgG1 Species Reactivity: Human
- Others not known
- Epitope: C-terminal Immunogen: Recombinant protein corresponding to C-terminal region of human perforin Molecular Weight: 70kDa Positive Control: Lymphoma Cellular Localization: Granular and cytoplasmic Recommended for: Immunohistochemistry (Formalin/paraffin) General References: 1
- Lichtenheld M G, et al
- (1988) Nature, 335:448-451
- 2
- Hameed A, et
- al
- American Journal of Pathology, 1992, 140(5):1025-30.
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Antigen: Perforin Ab-2
Applications: Immunohistochemistry (Paraffin)
Conjugate: Unconjugated
Regulatory Status: IVD
Target Species: Human
Isotype: IgG1
Clone: 5B10
Classification: Monoclonal
Host Species: Mouse
Research Discipline: T-Cell
Immunogen: Recombinant protein corresponding to C-terminal region of human perforin
Primary or Secondary: Primary
Antigen:
Perforin Ab-2
Applications:
Immunohistochemistry (Paraffin)
Conjugate:
Unconjugated
Regulatory Status:
IVD
Target Species:
Human
Isotype:
IgG1
Clone:
5B10
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Monoclonal
Host Species:
Mouse
Research Discipline:
T-Cell
Immunogen:
Recombinant protein corresponding to C-terminal region of human perforin
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Isotype: __
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Host Species: __
Research Discipline: __
Immunogen: __
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__
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__
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__
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