4657588
CD27 Mouse anti-Human, Brilliant Violet 510, Clone: L128, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD27
Applications
Flow Cytometry
Conjugate
Brilliant Violet 510
Regulatory Status
RUO
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype
IgG1
Purification Method
Affinity Purified
Description
TNFRSF7; Tumor necrosis factor receptor superfamily, member 7; Tp55; S152
Clone
L128
Classification
Monoclonal
Host Species
Mouse
Target Species
Human
Immunogen
Human Activated Peripheral Blood Cells
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The L128 monoclonal antibody specifically binds to human CD27
- CD27 is a 55-kDa disulfide-linked dimer that is a member of the nerve growth factor (NGF) super family
- This family also includes CD40, rat OX40, tumor necrosis factor (TNF) receptors and CD95 (Fas)
- With its ligand CD70, CD27 acts in a co-stimulatory fashion on T lymphocytes
- Present on most peripheral blood T lymphocytes and medullary thymocytes, the CD27 antigen is upregulated upon activation with the release of a soluble form, 28 to 32 kDa
- It is also detected on a subpopulation of approximately 33% of circulating B lymphocytes
- Following exposure to antigens, CD45RA+ T lymphocytes respond by upregulating the CD27 antigen
- After maximal stimulation, the CD27 antigen cannot be re-expressed on long-term cultures or on CD45RA-CD27+ T lymphocytes
- The CD4+CD27- population is contained within the memory CD45RO+ subset that proliferates after exposure to allergens
- Two subpopulations of B lymphocytes bearing the CD27 antigen secrete IgM (δ+) and IgG (δ-).
Compare Similar Items
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Antigen: CD27
Applications: Flow Cytometry
Conjugate: Brilliant Violet 510
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype: IgG1
Purification Method: Affinity Purified
Description: TNFRSF7; Tumor necrosis factor receptor superfamily, member 7; Tp55; S152
Clone: L128
Classification: Monoclonal
Host Species: Mouse
Target Species: Human
Immunogen: Human Activated Peripheral Blood Cells
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD27
Applications:
Flow Cytometry
Conjugate:
Brilliant Violet 510
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype:
IgG1
Purification Method:
Affinity Purified
Description:
TNFRSF7; Tumor necrosis factor receptor superfamily, member 7; Tp55; S152
Clone:
L128
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Immunogen:
Human Activated Peripheral Blood Cells
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: HLA-DR
Applications: Flow Cytometry
Conjugate: Brilliant Violet 605
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype: IgG2a κ
Purification Method: Affinity Purified
Description: MHC class II antigen; HLA class II histocompatibility antigen
Clone: G46-6
Classification: Monoclonal
Host Species: Mouse
Target Species: Baboon, Cynomolgus, Human, Rhesus Monkey
Immunogen: __
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
HLA-DR
Applications:
Flow Cytometry
Conjugate:
Brilliant Violet 605
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype:
IgG2a κ
Purification Method:
Affinity Purified
Description:
MHC class II antigen; HLA class II histocompatibility antigen
Clone:
G46-6
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey
Immunogen:
__
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: __
Applications: __
Conjugate: __
Regulatory Status: __
Formulation: __
Isotype: __
Purification Method: Carbon filtration, reverse osmosis
Description: __
Clone: __
Classification: __
Host Species: __
Target Species: __
Immunogen: __
Primary or Secondary: __
Content And Storage: __
Antigen:
__
Applications:
__
Conjugate:
__
Regulatory Status:
__
Formulation:
__
Isotype:
__
Purification Method:
Carbon filtration, reverse osmosis
Description:
__
Clone:
__
Classification:
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Host Species:
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Target Species:
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Immunogen:
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Primary or Secondary:
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Content And Storage:
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Antigen: __
Applications: __
Conjugate: __
Regulatory Status: __
Formulation: __
Isotype: __
Purification Method: Carbon filtration, deionization
Description: __
Clone: __
Classification: __
Host Species: __
Target Species: __
Immunogen: __
Primary or Secondary: __
Content And Storage: __
Antigen:
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Applications:
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Conjugate:
__
Regulatory Status:
__
Formulation:
__
Isotype:
__
Purification Method:
Carbon filtration, deionization
Description:
__
Clone:
__
Classification:
__
Host Species:
__
Target Species:
__
Immunogen:
__
Primary or Secondary:
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Content And Storage:
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