CD56 Mouse anti-Human, BB515, Clone: B159, BD

Description

• The B159 monoclonal antibody specifically binds to CD56
• CD56 is a heavily glycosylated adhesion protein that is present on a subpopulation of peripheral blood large granular lymphocytes that demonstrate natural killer activity
• CD56 is also expressed on a subset of T cells but is not expressed on myeloid cells, erythrocytes or B cells
• This antigen is a pan-NK-cell marker
• CD56 is virtually identical to an isoform of the neural cell adhesion molecule (NCAM), a structure mediating homotypic and heterotypic cell-cell interactions
• The antibody was conjugated to BD Horizon™ BB515 which was developed exclusively by BD Biosciences
• With an excitation max of 490nm and an emission max of 515nm, BD Horizon BB515 can be excited by the 488nm laser and detected in a standard FITC set (e.g., 530/30-nm filter)
• This dye provides a much brighter alternative to FITC with less spillover into the PE detector.