50-112-2620
Placental Alkaline Phosphatase Monoclonal Antibody (8B6), Biotin, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-2620-Each-of-1 | In Stock | ₹ 34,224.00 |
50-112-2620 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 34,224.00
GST (18%): ₹ 6,160.32
Total Price: ₹ 40,384.32
Antigen
Placental Alkaline Phosphatase
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P05187
Gene Symbols
ALPP
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
250
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone
8B6
Conjugate
Biotin
Gene
ALPP
Gene Alias
Alkaline phosphatase placental type; Alkaline phosphatase Regan isozyme; alkaline phosphatase, placental; alkaline phosphatase, placental type; alkaline phosphomonoesterase; ALP; Alp1; ALPP; AP-TNAP; DOA1; FLJ11281; FLJ40094; FLJ61142; FLJ93059; Germ-cell alkaline phosphatase; glycerophosphatase; HOPS; MGC161443; MGC167935; nagao Isozyme; P PLAP; PALP; PLA2P; PLAA; placental alkaline phosphatase 1; placental heat-stable alkaline phosphatase; PLAP; PLAP1; PLAP-1; rCG23846-like; Regan isozyme; TNAP; TNSALP
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: The monoclonal antibody 8B6 recognizes human Placental Alkaline Phosphatase (PLAP), a 130 (or 130 with 65 kDa) enzyme expressed by placental syncytiotrophoblastoid cells
- This enzyme has slightly different enzyme kinetics from other phosphatases
- PLAP can be found anchored to the plasma membrane in addition to the cytoplasm
- Expression is found in several germ line cancers; ovarian and testicular
- Expression is also present in human embryonic stem cells and bone marrow-derived mesenchymal stromal cells
- This 8B6 antibody reacts with both the Regan and Nagao isozymes
- Applications Reported: This 8B6 antibody has been reported for use in immunohistochemical staining of frozen (IHC-F) and formalin-fixed paraffin embedded (IHC-P) tissue, and ELISA
- Applications Tested: This 8B6 antibody has been tested by immunohistochemistry on formalin-fixed paraffin embedded (FFPE) human placenta with trypsin digestion
- This antibody can be used at less than or equal to 20 μg/mL
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Filtration: 0.2 μm post-manufacturing filtered
- Placental Alkaline Phosphatase plays an important role in the regulation of specific inflammatory disease processes
- There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney for this form of alkaline phosphatase have been well characterized
- Placental Alkaline Phosphatase reacts with a membrane-bound isoenzyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation
- Placental Alkaline Phosphatase is useful in the identification of testicular germ cell tumors
- Unlike germ cell tumors, PLAP-positive somatic cell tumors uniformly express epithelial membrane antigen (EMA)
- A proposed function of Placental Alkaline Phosphatase is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development
- Placental Alkaline Phosphatase has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects
- The character of hypophosphatasia can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms.
Compare Similar Items
Show Difference
Antigen: Placental Alkaline Phosphatase
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P05187
Gene Symbols: ALPP
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 250
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone: 8B6
Conjugate: Biotin
Gene: ALPP
Gene Alias: Alkaline phosphatase placental type; Alkaline phosphatase Regan isozyme; alkaline phosphatase, placental; alkaline phosphatase, placental type; alkaline phosphomonoesterase; ALP; Alp1; ALPP; AP-TNAP; DOA1; FLJ11281; FLJ40094; FLJ61142; FLJ93059; Germ-cell alkaline phosphatase; glycerophosphatase; HOPS; MGC161443; MGC167935; nagao Isozyme; P PLAP; PALP; PLA2P; PLAA; placental alkaline phosphatase 1; placental heat-stable alkaline phosphatase; PLAP; PLAP1; PLAP-1; rCG23846-like; Regan isozyme; TNAP; TNSALP
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
Placental Alkaline Phosphatase
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P05187
Gene Symbols:
ALPP
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
250
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone:
8B6
Conjugate:
Biotin
Gene:
ALPP
Gene Alias:
Alkaline phosphatase placental type; Alkaline phosphatase Regan isozyme; alkaline phosphatase, placental; alkaline phosphatase, placental type; alkaline phosphomonoesterase; ALP; Alp1; ALPP; AP-TNAP; DOA1; FLJ11281; FLJ40094; FLJ61142; FLJ93059; Germ-cell alkaline phosphatase; glycerophosphatase; HOPS; MGC161443; MGC167935; nagao Isozyme; P PLAP; PALP; PLA2P; PLAA; placental alkaline phosphatase 1; placental heat-stable alkaline phosphatase; PLAP; PLAP1; PLAP-1; rCG23846-like; Regan isozyme; TNAP; TNSALP
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: CD25
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P01590
Gene Symbols: IL2RA
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16184
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry
Clone: PC61.5
Conjugate: Unconjugated
Gene: IL2RA
Gene Alias: ADA; ADA1; Adenosine aminohydrolase; adenosine deaminase; CD25; CD25 antigen; cytokine receptor; IDDM10; IL 2 RA; IL 2 receptor; IL 2R; IL 2R subunit alpha; IL2 RA; IL2 RA antibody; IL2 receptor; il-2 receptor alpha; IL-2 Receptor alpha chain; IL-2 receptor alpha subunit; IL2 receptor subunit alpha; IL-2 receptor subunit alpha; IL2R; IL-2R alpha; IL-2R alpha chain; IL2R subunit alpha; IL-2R subunit alpha; Il2ra; IL-2RA; IL-2-RA; IL2-RA; Il2ra antibody; IL2RAC; IMD41; interleukin 2 receptor; interleukin 2 receptor alpha chain; interleukin 2 receptor subunit alpha; interleukin 2 receptor, alpha; interleukin 2 receptor, alpha chain; interleukin-2 receptor alpha; interleukin-2 receptor alpha chain; interleukin-2 receptor alpha subunit; interleukin-2 receptor beta chain; Interleukin2 receptor subunit alpha; interleukin-2 receptor subunit alpha; Ly-43; p55; p55 chain; sIL 2R; soluble IL 2 receptor; TAC antigen; TCGFR
Host Species: Rat
Quantity: 1 mg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG1 λ
Antigen:
CD25
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P01590
Gene Symbols:
IL2RA
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16184
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
PC61.5
Conjugate:
Unconjugated
Gene:
IL2RA
Gene Alias:
ADA; ADA1; Adenosine aminohydrolase; adenosine deaminase; CD25; CD25 antigen; cytokine receptor; IDDM10; IL 2 RA; IL 2 receptor; IL 2R; IL 2R subunit alpha; IL2 RA; IL2 RA antibody; IL2 receptor; il-2 receptor alpha; IL-2 Receptor alpha chain; IL-2 receptor alpha subunit; IL2 receptor subunit alpha; IL-2 receptor subunit alpha; IL2R; IL-2R alpha; IL-2R alpha chain; IL2R subunit alpha; IL-2R subunit alpha; Il2ra; IL-2RA; IL-2-RA; IL2-RA; Il2ra antibody; IL2RAC; IMD41; interleukin 2 receptor; interleukin 2 receptor alpha chain; interleukin 2 receptor subunit alpha; interleukin 2 receptor, alpha; interleukin 2 receptor, alpha chain; interleukin-2 receptor alpha; interleukin-2 receptor alpha chain; interleukin-2 receptor alpha subunit; interleukin-2 receptor beta chain; Interleukin2 receptor subunit alpha; interleukin-2 receptor subunit alpha; Ly-43; p55; p55 chain; sIL 2R; soluble IL 2 receptor; TAC antigen; TCGFR
Host Species:
Rat
Quantity:
1 mg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG1 λ
Antigen: CD33
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P20138
Gene Symbols: CD33
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 945
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunoprecipitation
Clone: WM-53 (WM53)
Conjugate: Unconjugated
Gene: CD33
Gene Alias: CD33; CD33 antigen; CD33 antigen (gp67); CD33 molecule; CD33 molecule transcript; FLJ00391; gp67; Myeloid cell surface antigen CD33; p67; sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; SIGLEC3; Siglec-3
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD33
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P20138
Gene Symbols:
CD33
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
945
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation
Clone:
WM-53 (WM53)
Conjugate:
Unconjugated
Gene:
CD33
Gene Alias:
CD33; CD33 antigen; CD33 antigen (gp67); CD33 molecule; CD33 molecule transcript; FLJ00391; gp67; Myeloid cell surface antigen CD33; p67; sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; SIGLEC3; Siglec-3
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD68
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P31996
Gene Symbols: Cd68
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12514
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen)
Clone: FA-11
Conjugate: Unconjugated
Gene: Cd68
Gene Alias: CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen
Host Species: Rat
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD68
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P31996
Gene Symbols:
Cd68
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12514
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen)
Clone:
FA-11
Conjugate:
Unconjugated
Gene:
Cd68
Gene Alias:
CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen
Host Species:
Rat
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ