50-112-3200
Phospho-STAT6 (Tyr641) Monoclonal Antibody (CHI2S4N), APC, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-3200-Each-of-1 | In Stock | ₹ 33,710.64 |
50-112-3200 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 33,710.64
GST (18%): ₹ 6,067.915
Total Price: ₹ 39,778.555
Antigen
Phospho-STAT6 (Tyr641)
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
P42226, P52633
Gene Symbols
STAT6
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
20852, 6778
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
CHI2S4N
Conjugate
APC
Gene
STAT6
Gene Alias
12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: This CHI2S4N monoclonal antibody recognizes human and mouse signal transducer and activator of transcription 6 (STAT6) when phosphorylated on tyrosine 641
- Following their phosphorylation by JAKs, STAT proteins translocate to the nucleus where they bind to DNA and regulate transcription of specific genes in a cell type- and cytokine-specific manner
- In response to IL-4, STAT6 is phosphorylated on tyrosine 641 by JAK1 and JAK3
- STAT6 signaling downstream of the IL-4 receptor promotes T cell growth and B cell production of IgE
- Specificity of this CHI2S4N clone was determined by ELISA and flow cytometry
- Applications Reported: This CHI2S4N antibody has been reported for use in intracellular staining followed by flow cytometric analysis
- Applications Tested: This CHI2S4N antibody has been pre-titrated and tested by intracellular staining followed by flow cytometric analysis of stimulated normal human peripheral blood cells
- This can be used at 5 μL (0.06 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Staining Protocol: We recommend using Protocol C: Two-step protocol: Fixation/Methanol
- Protocol A: Two-step protocol: intracellular (cytoplasmic) proteins and Protocol B: One-step protocol: intracellular (nuclear) proteins cannot be used
- STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL13
- (Stat6-/-) were found to be deficient in IL-4-mediated functions including Th2 helper T-cell differentiation, expression of cell surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4 mediated proliferation
- STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta
- STAT6 is critically involved in Th2 immune response
- STAT6 is crucial for IL-4-mediated biological responses, and naturally in two isoforms: STAT6a and STAT6c.
Compare Similar Items
Show Difference
Antigen: Phospho-STAT6 (Tyr641)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P42226, P52633
Gene Symbols: STAT6
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20852, 6778
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: CHI2S4N
Conjugate: APC
Gene: STAT6
Gene Alias: 12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
Phospho-STAT6 (Tyr641)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P42226, P52633
Gene Symbols:
STAT6
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20852, 6778
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
CHI2S4N
Conjugate:
APC
Gene:
STAT6
Gene Alias:
12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: Phospho-Syk (Tyr348)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P43405, P48025
Gene Symbols: Syk
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20963, 6850
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: moch1ct
Conjugate: APC
Gene: Syk
Gene Alias: DKFZp313N1010; EC 2.7.10.2; FLJ25043; FLJ37489; HGNC:11205; kinase Syk; KSYK; p72Syk; p72-Syk; ptk72; SP1; spleen associated tyrosine kinase; spleen tyrosine kinase; SYK; syk signaling; Sykb; tyrosine-kinase syk; tyrosine-protein kinase SYK
Host Species: Mouse
Quantity: 25 Tests
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
Phospho-Syk (Tyr348)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P43405, P48025
Gene Symbols:
Syk
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20963, 6850
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
moch1ct
Conjugate:
APC
Gene:
Syk
Gene Alias:
DKFZp313N1010; EC 2.7.10.2; FLJ25043; FLJ37489; HGNC:11205; kinase Syk; KSYK; p72Syk; p72-Syk; ptk72; SP1; spleen associated tyrosine kinase; spleen tyrosine kinase; SYK; syk signaling; Sykb; tyrosine-kinase syk; tyrosine-protein kinase SYK
Host Species:
Mouse
Quantity:
25 Tests
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: Phospho-Syk (Tyr348)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P43405, P48025
Gene Symbols: Syk
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20963, 6850
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: moch1ct
Conjugate: APC
Gene: Syk
Gene Alias: DKFZp313N1010; EC 2.7.10.2; FLJ25043; FLJ37489; HGNC:11205; kinase Syk; KSYK; p72Syk; p72-Syk; ptk72; SP1; spleen associated tyrosine kinase; spleen tyrosine kinase; SYK; syk signaling; Sykb; tyrosine-kinase syk; tyrosine-protein kinase SYK
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
Phospho-Syk (Tyr348)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P43405, P48025
Gene Symbols:
Syk
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20963, 6850
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
moch1ct
Conjugate:
APC
Gene:
Syk
Gene Alias:
DKFZp313N1010; EC 2.7.10.2; FLJ25043; FLJ37489; HGNC:11205; kinase Syk; KSYK; p72Syk; p72-Syk; ptk72; SP1; spleen associated tyrosine kinase; spleen tyrosine kinase; SYK; syk signaling; Sykb; tyrosine-kinase syk; tyrosine-protein kinase SYK
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: Phospho-STAT4 (Tyr693)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P42228, Q14765
Gene Symbols: STAT4
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20849, 6775
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 4LURPIE
Conjugate: APC
Gene: STAT4
Gene Alias: CIS4; HSPC060; OTTHUMP00000163553; Signal transducer and activator of transcription 4; SLEB11; SOCS4; SOCS6; SSI4; STAI4; STAT; Stat4; STATI4
Host Species: Mouse
Quantity: 25 Tests
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
Phospho-STAT4 (Tyr693)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P42228, Q14765
Gene Symbols:
STAT4
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20849, 6775
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
4LURPIE
Conjugate:
APC
Gene:
STAT4
Gene Alias:
CIS4; HSPC060; OTTHUMP00000163553; Signal transducer and activator of transcription 4; SLEB11; SOCS4; SOCS6; SSI4; STAI4; STAT; Stat4; STATI4
Host Species:
Mouse
Quantity:
25 Tests
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1 κ