50-112-8983
Phospho-STAT6 (Tyr641) Monoclonal Antibody (CHI2S4N), APC, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-8983-Each-of-1 | In Stock | ₹ 13,946.28 |
50-112-8983 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 13,946.28
GST (18%): ₹ 2,510.33
Total Price: ₹ 16,456.61
Antigen
Phospho-STAT6 (Tyr641)
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
P42226, P52633
Gene Symbols
STAT6
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
20852, 6778
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
CHI2S4N
Conjugate
APC
Gene
STAT6
Gene Alias
12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT
Host Species
Mouse
Quantity
25 Tests
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: This CHI2S4N monoclonal antibody recognizes human and mouse signal transducer and activator of transcription 6 (STAT6) when phosphorylated on tyrosine 641
- Following their phosphorylation by JAKs, STAT proteins translocate to the nucleus where they bind to DNA and regulate transcription of specific genes in a cell type- and cytokine-specific manner
- In response to IL-4, STAT6 is phosphorylated on tyrosine 641 by JAK1 and JAK3
- STAT6 signaling downstream of the IL-4 receptor promotes T cell growth and B cell production of IgE
- Specificity of this CHI2S4N clone was determined by ELISA and flow cytometry
- Applications Reported: This CHI2S4N antibody has been reported for use in intracellular staining followed by flow cytometric analysis
- Applications Tested: This CHI2S4N antibody has been pre-titrated and tested by intracellular staining followed by flow cytometric analysis of stimulated normal human peripheral blood cells
- This can be used at 5 μL (0.06 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Staining Protocol: We recommend using Protocol C: Two-step protocol: Fixation/Methanol
- Protocol A: Two-step protocol: intracellular (cytoplasmic) proteins and Protocol B: One-step protocol: intracellular (nuclear) proteins cannot be used
- STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL13
- (Stat6-/-) were found to be deficient in IL-4-mediated functions including Th2 helper T-cell differentiation, expression of cell surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4 mediated proliferation
- STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta
- STAT6 is critically involved in Th2 immune response
- STAT6 is crucial for IL-4-mediated biological responses, and naturally in two isoforms: STAT6a and STAT6c.
Compare Similar Items
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Antigen: Phospho-STAT6 (Tyr641)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P42226, P52633
Gene Symbols: STAT6
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20852, 6778
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: CHI2S4N
Conjugate: APC
Gene: STAT6
Gene Alias: 12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT
Host Species: Mouse
Quantity: 25 Tests
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
Phospho-STAT6 (Tyr641)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P42226, P52633
Gene Symbols:
STAT6
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20852, 6778
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
CHI2S4N
Conjugate:
APC
Gene:
STAT6
Gene Alias:
12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT
Host Species:
Mouse
Quantity:
25 Tests
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: CD279 (PD-1)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q02242
Gene Symbols: Pdcd1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18566
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: J43
Conjugate: PerCP-eFluor 710
Gene: Pdcd1
Gene Alias: CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2
Host Species: Armenian Hamster
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
CD279 (PD-1)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q02242
Gene Symbols:
Pdcd1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18566
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
J43
Conjugate:
PerCP-eFluor 710
Gene:
Pdcd1
Gene Alias:
CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2
Host Species:
Armenian Hamster
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: CD115 (c-fms)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P09581
Gene Symbols: Csf1r
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12978
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: AFS98
Conjugate: PE-Cyanine7
Gene: Csf1r
Gene Alias: AI323359; CD115; CD115 antigen; C-FMS; colony stimulating factor 1 receptor; colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog; CSF-1 receptor; CSF1R; CSF-1R; CSF-1-R; CSFIR; Csfmr; CSFR; EC 2.7.10.1; FIM2; Fim-2; FMS; fms proto-oncogene; HDLS; kinase CSFR; macrophage colony stimulating factor I receptor; macrophage colony-stimulating factor 1 receptor; McDonough feline sarcoma viral (v-fms) oncogene homolog; M-CSFR; M-CSF-R; mrfms; OTTHUMP00000224093; protein-tyrosine kinase; proto-oncogene c-Fms; proto-oncogene fms
Host Species: Rat
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD115 (c-fms)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P09581
Gene Symbols:
Csf1r
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12978
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
AFS98
Conjugate:
PE-Cyanine7
Gene:
Csf1r
Gene Alias:
AI323359; CD115; CD115 antigen; C-FMS; colony stimulating factor 1 receptor; colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog; CSF-1 receptor; CSF1R; CSF-1R; CSF-1-R; CSFIR; Csfmr; CSFR; EC 2.7.10.1; FIM2; Fim-2; FMS; fms proto-oncogene; HDLS; kinase CSFR; macrophage colony stimulating factor I receptor; macrophage colony-stimulating factor 1 receptor; McDonough feline sarcoma viral (v-fms) oncogene homolog; M-CSFR; M-CSF-R; mrfms; OTTHUMP00000224093; protein-tyrosine kinase; proto-oncogene c-Fms; proto-oncogene fms
Host Species:
Rat
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: CD14
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P08571
Gene Symbols: Cd14
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 929
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 61D3
Conjugate: PE-Cyanine5
Gene: Cd14
Gene Alias: CD 14; CD14; CD14 antigen; CD14 molecule; cd14 monocyte; lipopolysaccharide receptor; lipoprotein receptor; LPSR antibody; monocyte differentiation antigen CD14; Monocyte differentiation antigen CD14, membrane-bound form; Monocyte differentiation antigen CD14, urinary form; monocyte differentiation antigen CD14; LOW QUALITY PROTEIN: monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein; myeloid membrane glycoprotein precursor; sCD14; soluble CD14
Host Species: Mouse
Quantity: 25 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD14
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P08571
Gene Symbols:
Cd14
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
929
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
61D3
Conjugate:
PE-Cyanine5
Gene:
Cd14
Gene Alias:
CD 14; CD14; CD14 antigen; CD14 molecule; cd14 monocyte; lipopolysaccharide receptor; lipoprotein receptor; LPSR antibody; monocyte differentiation antigen CD14; Monocyte differentiation antigen CD14, membrane-bound form; Monocyte differentiation antigen CD14, urinary form; monocyte differentiation antigen CD14; LOW QUALITY PROTEIN: monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein; myeloid membrane glycoprotein precursor; sCD14; soluble CD14
Host Species:
Mouse
Quantity:
25 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ