50-112-4169
CD218a (IL-18Ra) Monoclonal Antibody (P3TUNYA), eFluor™ 450, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-4169-Each-of-1 | In Stock | ₹ 33,710.64 |
50-112-4169 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 33,710.64
GST (18%): ₹ 6,067.915
Total Price: ₹ 39,778.555
Antigen
CD218a (IL-18Ra)
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q61098
Gene Symbols
Il18r1
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16182
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
P3TUNYA
Conjugate
eFluor 450
Gene
Il18r1
Gene Alias
CD218 antigen-like family member A; CD218a; CDw218a; cytokine receptor; IL1 receptor-related protein; Il18r1; IL-18R1; IL-18R-1; IL18RA; Il18ralpha; IL-18R-alpha; IL18Ralpha2; IL1RRP; IL-1Rrp; IL1R-rp; interleukin 1 receptor related protein; interleukin 18 receptor 1; Interleukin-18; interleukin-18 receptor 1; Interleukin-18 receptor alpha
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: This P3TUNYA monoclonal antibody reacts with mouse CD218a (Interleukin 18 Receptor alpha)
- CD218a is one of the subunits of the heterodimeric receptor complex for the IL-18 cytokine
- IL-18 is a proinflammatory cytokine and member of the IL-1 family first identified by its role in IFN gamma secretion during toxic shock
- Like the other members of the family, it is synthesized as an inactive precursor which requires cleavage by caspases prior to secretion of the active form
- It is secreted by activated monocytes, macrophages, epithelial cells, and keratinocytes via a non-classical pathway
- IL-18 Receptor is expressed on Th1, but not naive CD4 T cells or Th2, as well as subsets of NK cells and neutrophils
- The heterodimeric receptor is made up of a ligand-binding alpha chain and signal-transducing beta chain
- On its own, IL-18Ra binds IL-18 with low affinity, although the affinity of this interaction increases upon forming a complex with IL-18Rb
- IL-18R signaling plays a critical role in Th1 differentiation and effector function, and results in the increased expression of IFN gamma, TNF alpha, and Fas ligand from T cells and NK cells
- IL-18 has also been found to synergize with IL-23 in the development and function of Th17 cells
- Recently, a subset of CD8 T cells has been discovered that co-secretes IFN gamma with IL-17A and sometimes IL-22
- These Tc17 cells share key transcription factors, chemokine receptors, and cytokine receptors with Th17 cells
- IL18R1 is a cytokine receptor that belongs to the interleukin 1 receptor family
- This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction
- IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells
- The gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q.
Compare Similar Items
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Antigen: CD218a (IL-18Ra)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q61098
Gene Symbols: Il18r1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16182
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: P3TUNYA
Conjugate: eFluor 450
Gene: Il18r1
Gene Alias: CD218 antigen-like family member A; CD218a; CDw218a; cytokine receptor; IL1 receptor-related protein; Il18r1; IL-18R1; IL-18R-1; IL18RA; Il18ralpha; IL-18R-alpha; IL18Ralpha2; IL1RRP; IL-1Rrp; IL1R-rp; interleukin 1 receptor related protein; interleukin 18 receptor 1; Interleukin-18; interleukin-18 receptor 1; Interleukin-18 receptor alpha
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD218a (IL-18Ra)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q61098
Gene Symbols:
Il18r1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16182
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
P3TUNYA
Conjugate:
eFluor 450
Gene:
Il18r1
Gene Alias:
CD218 antigen-like family member A; CD218a; CDw218a; cytokine receptor; IL1 receptor-related protein; Il18r1; IL-18R1; IL-18R-1; IL18RA; Il18ralpha; IL-18R-alpha; IL18Ralpha2; IL1RRP; IL-1Rrp; IL1R-rp; interleukin 1 receptor related protein; interleukin 18 receptor 1; Interleukin-18; interleukin-18 receptor 1; Interleukin-18 receptor alpha
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: Granzyme A
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P11032
Gene Symbols: GZMA
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14938
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: GzA-3G8.5
Conjugate: eFluor 450
Gene: GZMA
Gene Alias: Autocrine thymic lymphoma granzyme-like serine protease; AW494114; BLT esterase; CTL tryptase; CTLA3; CTLA-3; Cytotoxic T-lymphocyte proteinase 1; Cytotoxic T-lymphocyte-associated serine esterase-3; fragmentin-1; granzyme 1; granzyme A; Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3; Hanukah factor serine protease); granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3); Granzyme-1; GZMA; H factor; Hanukah factor; Hanukah factor serine protease); Hanukkah factor; Hf; HFSP; Mtsp-1; SE1; serine esterase 1; t cell-specific serine protease 1; TSP1; TSP-1
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
Granzyme A
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P11032
Gene Symbols:
GZMA
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14938
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
GzA-3G8.5
Conjugate:
eFluor 450
Gene:
GZMA
Gene Alias:
Autocrine thymic lymphoma granzyme-like serine protease; AW494114; BLT esterase; CTL tryptase; CTLA3; CTLA-3; Cytotoxic T-lymphocyte proteinase 1; Cytotoxic T-lymphocyte-associated serine esterase-3; fragmentin-1; granzyme 1; granzyme A; Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3; Hanukah factor serine protease); granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3); Granzyme-1; GZMA; H factor; Hanukah factor; Hanukah factor serine protease); Hanukkah factor; Hf; HFSP; Mtsp-1; SE1; serine esterase 1; t cell-specific serine protease 1; TSP1; TSP-1
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: CD93 (AA4.1)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: O89103
Gene Symbols: Cd93
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17064
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: AA4.1
Conjugate: eFluor 450
Gene: Cd93
Gene Alias: 6030404G09Rik; AA145088; Aa4; AA4.1; AW555904; C1q receptor; C1q receptor 1; C1q/MBL/SPA receptor; C1qR; C1qR(P); C1qr1; C1qRP; Cd93; CD93 antigen; CD93 molecule; CDw93; Cell surface antigen AA4; complement component 1 q subcomponent receptor 1; complement component 1, q subcomponent, receptor 1; complement component C1q receptor; dJ737E23.1; ECSM3; Ly68; ly-68; Lymphocyte antigen 68; matrix-remodeling-associated protein 4; matrix-remodelling associated 4; MXRA4
Host Species: Rat
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
CD93 (AA4.1)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
O89103
Gene Symbols:
Cd93
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17064
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
AA4.1
Conjugate:
eFluor 450
Gene:
Cd93
Gene Alias:
6030404G09Rik; AA145088; Aa4; AA4.1; AW555904; C1q receptor; C1q receptor 1; C1q/MBL/SPA receptor; C1qR; C1qR(P); C1qr1; C1qRP; Cd93; CD93 antigen; CD93 molecule; CDw93; Cell surface antigen AA4; complement component 1 q subcomponent receptor 1; complement component 1, q subcomponent, receptor 1; complement component C1q receptor; dJ737E23.1; ECSM3; Ly68; ly-68; Lymphocyte antigen 68; matrix-remodeling-associated protein 4; matrix-remodelling associated 4; MXRA4
Host Species:
Rat
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: FceR1 alpha
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P20489
Gene Symbols: FCER1A
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14125
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: MAR-1
Conjugate: eFluor 450
Gene: FCER1A
Gene Alias: alpha polypeptide; fc epsilon r1; Fc epsilon receptor Ia; Fc epsilon RI alpha-chain; Fc fragment of IgE receptor Ia; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; Fc IgE receptor, alpha polypeptide; Fc receptor, IgE, high affinity I, alpha polypeptide; Fce1a; Fc-epsilon RI-alpha; fcepsilonri; FCER1A; FcERI; Fcr-5; high affinity immunoglobulin epsilon receptor alpha-subunit; high affinity immunoglobulin epsilon receptor subunit alpha; IgE Fc receptor subunit alpha; Iger01; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide; RATIGER01; RP11-550P17.3
Host Species: Armenian Hamster
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
FceR1 alpha
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P20489
Gene Symbols:
FCER1A
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14125
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
MAR-1
Conjugate:
eFluor 450
Gene:
FCER1A
Gene Alias:
alpha polypeptide; fc epsilon r1; Fc epsilon receptor Ia; Fc epsilon RI alpha-chain; Fc fragment of IgE receptor Ia; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; Fc IgE receptor, alpha polypeptide; Fc receptor, IgE, high affinity I, alpha polypeptide; Fce1a; Fc-epsilon RI-alpha; fcepsilonri; FCER1A; FcERI; Fcr-5; high affinity immunoglobulin epsilon receptor alpha-subunit; high affinity immunoglobulin epsilon receptor subunit alpha; IgE Fc receptor subunit alpha; Iger01; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide; RATIGER01; RP11-550P17.3
Host Species:
Armenian Hamster
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG