50-112-8656

CD200 Receptor Monoclonal Antibody (OX108), PerCP-eFluor™ 710, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-112-8656-Each-of-1 In Stock ₹ 35,764.08

50-112-8656 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

CD200 Receptor

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

Q8TD46

Gene Symbols

CD200R1

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

131450

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

OX108

Conjugate

PerCP-eFluor 710

Gene

CD200R1

Gene Alias

antigen identified by monoclonal antibody MRC OX-2 receptor; CD200 cell surface glycoprotein receptor; CD200 R1; CD200 receptor 1; CD200R; Cd200r1; Cell surface glycoprotein CD200 receptor 1; cell surface glycoprotein OX2 receptor 1; cell surface glycoprotein receptor CD200; CRTR2; HCRTR2; MOX2 receptor; MOX2R; Orexin receptor 2; OX102 antigen; OX2 receptor; OX2R; UNQ2522/PRO6015

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description: The monoclonal antibody OX108 recognizes human CD200R also known as OX2
  • CD200R is an inhibitory receptor with a similar structure as its ligand, CD200, yet lacks an ITIM domain typically found in inhibitory receptors
  • Instead the CD200R cytoplasmic domain contains a novel phosphotyrosine binding domain, NPXY, which after binding SHIP inhibits ERK, JNK and MAPK p38 pathways
  • In activated macrophages signaling results in inhibition of TNFalpha secretion
  • Isoforms of CD200R have been identified and are thought to play a major role in differentiation, especially in regards to tolerogenic DCs
  • Expression is restricted to hematopoietic cells: myeloid cells (monocytes, macrophages, DCs, neutrophils, mast cells and basophils) and a subset of T lymphocytes as well as langerhans (LC) cells and dendritic epidermal T cells
  • The epitope of OX108 is thought to be near the binding site of CD200
  • Applications Reported: This OX108 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This OX108 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells
  • This can be used at 5 μL (0.5 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • CD200R (OX2R) is a receptor for the OX-2 membrane glycoprotein, and both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains
  • CD200R is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal
  • In mouse, CD200R is expressed primarily by peripheral blood monocytes and neutophils but also by other leucocytes including T-lymphocytes and mast cells
  • Further mouse studies of a gene related to CD200R suggests that the receptor may control myeloid function in a tissue-specific manner
  • Alternative splicing of CD200R results in multiple transcript variants
  • Diseases associated with CD200R dysfunction include primary hypertrophic osteoarthropathy.

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Antigen:
CD200 Receptor

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q8TD46

Gene Symbols:
CD200R1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
131450

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
OX108

Conjugate:
PerCP-eFluor 710

Gene:
CD200R1

Gene Alias:
antigen identified by monoclonal antibody MRC OX-2 receptor; CD200 cell surface glycoprotein receptor; CD200 R1; CD200 receptor 1; CD200R; Cd200r1; Cell surface glycoprotein CD200 receptor 1; cell surface glycoprotein OX2 receptor 1; cell surface glycoprotein receptor CD200; CRTR2; HCRTR2; MOX2 receptor; MOX2R; Orexin receptor 2; OX102 antigen; OX2 receptor; OX2R; UNQ2522/PRO6015

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

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Antigen:
CD137 (4-1BB)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P20334

Gene Symbols:
TNFRSF9

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21942

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
17B5

Conjugate:
APC

Gene:
TNFRSF9

Gene Alias:
4 1 BB; 41BB; 4-1BB; 4-1BB ligand receptor; A930040I11Rik; AA408498; AI325004; Cd137; CD137 antigen; CDw137; EGK_00183; homolog of mouse 4-1BB; ILA; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; Ly63; receptor protein 4-1BB; s4 1 BB; s4 1BB; s41BB; sCD137; secreted CD137 antigen; soluble 4 1 BB; soluble 4 1BB; soluble 41BB; soluble CD137; T cell antigen ILA; T-cell antigen 4-1BB; T-cell antigen 4-1BB homolog; T-cell antigen ILA; TNF receptor superfamily member 9; TNFRSF9; Tumor necrosis factor receptor superfamily member 9; tumor necrosis factor receptor superfamily, member 9

Host Species:
Syrian Hamster

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

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Antigen:
Phospho-STAT5 (Tyr694)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P42229, P42230

Gene Symbols:
STAT5A

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20850, 6776

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
SRBCZX

Conjugate:
PE

Gene:
STAT5A

Gene Alias:
AA959963; mammary gland factor; mammary gland factor STAT5A; mammary gland factor; transcription factor; Mgf; Mpf; signal transducer and activator of transcription 5; signal transducer and activator of transcription 5a; signal transducer and activator of transcription factor 5A; STAT; STAT5; STAT5A; STAT5A, Mammary Gland Factor; STAT5A/MGF; STAT5B; STATA5

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

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Antigen:
CD185 (CXCR5)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P32302

Gene Symbols:
CXCR5

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
643, 701792

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MU5UBEE

Conjugate:
PE

Gene:
CXCR5

Gene Alias:
Blr1; Blr-1; Burkitt lymphoma receptor 1; burkitt lymphoma receptor 1 homolog; Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5); Burkitt lymphoma receptor 1, GTP-binding protein; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD185; CD185 antigen; chemochine (C-X-C motif) receptor 5; chemokine (C-X-C motif) receptor 5; CXC; C-X-C chemokine receptor type 5; CXC motif chemokine; C-X-C motif chemokine receptor 5; CXCR5; CXC-R5; CXCR-5; EGK_06966; Fusin; Gpcr6; GPR9; HUMSTR; LESTR; MDR15; MDR-15; Monocyte-derived receptor 15; neurolymphatic receptor; NLR

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate, Rhesus Monkey

Product Type:
Antibody

Isotype:
IgG2b κ