50-112-9202

CD279 (PD-1) Monoclonal Antibody (eBioJ105 (J105)), eBioscience™, Invitrogen™

Manufacturer: Invitrogen

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Pack Size SKU Availability Price
Each 50-112-9202-Each In Stock ₹ 9,210.53

50-112-9202 - Each

₹ 9,210.53

In Stock

Quantity

1

Base Price: ₹ 9,210.53

GST (18%): ₹ 1,657.895

Total Price: ₹ 10,868.425

Antigen

CD279 (PD-1)

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

Q15116

Gene Symbols

Pdcd1

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100135775, 5133

Content And Storage

4° C

Form

Liquid

Applications

Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation

Clone

eBioJ105 (J105)

Conjugate

Unconjugated

Gene

Pdcd1

Gene Alias

CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2

Host Species

Mouse

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Human, Rhesus Monkey

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description: The J105 monoclonal antibody reacts with the human PD-1 (programmed death-1), a 55 kDa member of the CD28 immunoglobulin superfamily
  • PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease
  • PD-1 is expressed predomitly on activated T and B lymphocytes
  • Two novel members of the B7 family have been identified as the PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC)
  • Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells
  • Costaining experiments suggest that eBioJ105 recognizes a different epitope than MIH4 (cat
  • 11-9969)
  • Applications Reported: This eBioJ105 (J105) antibody has been reported for use in flow cytometric analysis, immunoprecipitation, and immunohistology staining of frozen tissue sections
  • Applications Tested: This eBioJ105 (J105) antibody has been tested by flow cytometic analysis of PHA stimulated normal human peripheral blood cells
  • This can be used at less than or equal to 1 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC)
  • T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC
  • PD-1 can bind two different but related ligands, PDL-1 and PDL-2
  • Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of &quotedanger signals&quote such as LPS or other molecules associated with bacteria or other pathogens
  • Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases
  • Despite its predicted molecular weight, PD-1 often migrates at higher molecular weight in SDS-PAGE.

Compare Similar Items

Show Difference

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Invitrogen

50-112-9202

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Antigen:
CD279 (PD-1)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q15116

Gene Symbols:
Pdcd1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100135775, 5133

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation

Clone:
eBioJ105 (J105)

Conjugate:
Unconjugated

Gene:
Pdcd1

Gene Alias:
CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2

Host Species:
Mouse

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Human, Rhesus Monkey

Product Type:
Antibody

Isotype:
IgG1 κ

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Invitrogen

50-112-9203

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Antigen:
IFN gamma

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.2

Gene Accession No.:
P01580

Gene Symbols:
IFNG

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15978

Content And Storage:
4° C

Form:
Liquid

Applications:
Functional Assay, Neutralization

Clone:
H22

Conjugate:
Functional Grade

Gene:
IFNG

Gene Alias:
BoIFNG; cytokine; EGK_03901; gamma interferon; gamma interferon precursor; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; IFG; IFI; IFN gamma; IFN ?; Ifng; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; interferon-gamma precursor; Interferon?; M-IFN-g; R-IFN-g

Host Species:
Armenian Hamster

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Invitrogen

50-112-9204

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Antigen:
CD244.2 (2B4)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q07763

Gene Symbols:
Cd244

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18106

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
eBio244F4

Conjugate:
APC

Gene:
Cd244

Gene Alias:
2B4; C9.1; Cd244; CD244 long isoform; CD244 natural killer cell receptor 2B4; CD244 short isoform; F730046O15Rik; Ly90; NAIL; natural killer cell receptor; natural killer cell receptor 2B4; NK cell receptor 2B4; NK cell type I receptor protein 2B4; NKR2B4; Nmrk; non MHC restricted killing associated; non-MHC restricted killing associated; Signaling lymphocytic activation molecule 4; SLAM family member 4; SLAMF4

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a

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Fischer Scientific

50-112-9205

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Antigen:
CD335 (NKp46)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q8C567

Gene Symbols:
NCR1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17086

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
29A1.4

Conjugate:
PE-Cyanine7

Gene:
NCR1

Gene Alias:
1-Mar; activating receptor 1; Ar1; CD335; hNKp46; Kilr1; KILR-1; LY94; Ly-94; lymphocyte antigen 94; Lymphocyte antigen 94 homolog; lymphocyte antigen 94 homolog (activating NK-receptor; lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46); mAR-1; MAR1 (mouse activating receptor 1); mNKp46; natural cytotoxicity triggering receptor 1; Natural killer cell p46-related protein; natural killer cell receptor; Ncr1; NK cell-activating receptor; NK receptor KILR-1; NKACTR; Nkp46; NK-p46; NK-p46); rAR-1; rat-activating receptor 1

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ