50-113-7023

CD11b Monoclonal Antibody (M1/70), APC-Cyanine7, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-113-7023-Each-of-1 In Stock ₹ 28,234.80

50-113-7023 - Each of 1

₹ 28,234.80

In Stock

Quantity

1

Base Price: ₹ 28,234.80

GST (18%): ₹ 5,082.264

Total Price: ₹ 33,317.064

Antigen

CD11b

Classification

Monoclonal

Concentration

0.1 mg/mL

Formulation

PBS with proprietary stabilizer and <0.1% sodium azide

Gene Accession No.

P05555, P11215

Gene Symbols

ITGAM, LOC100351865

Immunogen

C57BL/10 splenic T cells and concanavalin A stimulated C57BL/10 splenocytes.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Baboon, Human, Mouse, Rabbit, Rhesus Monkey

Product Type

Antibody

Isotype

IgG2b κ

Applications

Flow Cytometry

Clone

M1/70

Conjugate

APC-Cyanine7

Gene

ITGAM

Gene Alias

antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; LOC100351865; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product

Host Species

Rat

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

100351865, 16409, 3684, 714832

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

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Description

  • CD11b (integrin alpha-M, ITGAM, integrin alpha-X, ITGAX) is a 165 kDa adhesion molecule that associates non-covalently with integrin beta-2 (CD18)
  • The CD11b/CD18 heterodimeric complex is also known as integrin alpha-M beta-2, Mac-1, and CR3 (complement receptor 3)
  • CD11b is expressed on the surface of monocytes/macrophages, granulocytes, activated lymphocytes, a subset of NK cells, a subset of dendritic cells, and microglia in the brain
  • CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X -these adhesions are critical for cell-cell and cell-matrix interactions
  • CD11b is expressed on 8% of spleen cells, 44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue
  • The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages
  • Further, peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages
  • Diseases associated with CD11b dysfunction include systemic lupus erythematosus 6 and ITGAM-related susceptibility to systemic lupus erythematosus.

Compare Similar Items

Show Difference

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Invitrogen

50-113-7023

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Antigen:
CD11b

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with proprietary stabilizer and <0.1% sodium azide

Gene Accession No.:
P05555, P11215

Gene Symbols:
ITGAM, LOC100351865

Immunogen:
C57BL/10 splenic T cells and concanavalin A stimulated C57BL/10 splenocytes.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Baboon, Human, Mouse, Rabbit, Rhesus Monkey

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
M1/70

Conjugate:
APC-Cyanine7

Gene:
ITGAM

Gene Alias:
antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; LOC100351865; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product

Host Species:
Rat

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
100351865, 16409, 3684, 714832

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

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Invitrogen

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Antigen:
ICAM-1

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with <0.1% sodium azide

Gene Accession No.:
P13597

Gene Symbols:
ICAM1

Immunogen:
Mouse NS-1 cells

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Porcine

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
YN1/1.7.4

Conjugate:
APC

Gene:
ICAM1

Gene Alias:
BB2; CD54; cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM; Icam1; ICAM-1; ICAM-1; CD54 homolog; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule-1; intercellular adhesion molecule-1 precursor; Ly 47; Ly-47; major group rhinovirus receptor; MALA2; MALA-2; MyD10; P3.58; sCD54; soluble CD54; Surface antigen of activated B cells

Host Species:
Rat

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
15894, 396750

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

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Invitrogen

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Antigen:
ICAM-1

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with <0.1% sodium azide

Gene Accession No.:
P13597

Gene Symbols:
ICAM1

Immunogen:
Mouse NS-1 cells

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Porcine

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
YN1/1.7.4

Conjugate:
Pacific Blue

Gene:
ICAM1

Gene Alias:
BB2; CD54; cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM; Icam1; ICAM-1; ICAM-1; CD54 homolog; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule-1; intercellular adhesion molecule-1 precursor; Ly 47; Ly-47; major group rhinovirus receptor; MALA2; MALA-2; MyD10; P3.58; sCD54; soluble CD54; Surface antigen of activated B cells

Host Species:
Rat

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
15894, 396750

Content And Storage:
4° C, store in dark

Form:
Liquid

Img

Invitrogen

50-113-7032

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Antigen:
CD86, CD86 (B7-2)

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with proprietary stabilizer and <0.1% sodium azide

Gene Accession No.:
P42082

Gene Symbols:
CD86

Immunogen:
Mouse CD86 from LPS-activated CBA/Ca mouse spleen B cells

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
GL1

Conjugate:
PE-Cyanine7

Gene:
CD86

Gene Alias:
activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2

Host Species:
Rat

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
12524

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid