50-113-7038
c-Kit Monoclonal Antibody (2B8), APC-Cyanine7, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-113-7038-Each-of-1 | In Stock | ₹ 24,555.72 |
50-113-7038 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,555.72
GST (18%): ₹ 4,420.03
Total Price: ₹ 28,975.75
Antigen
c-Kit
Classification
Monoclonal
Concentration
0.1 mg/mL
Formulation
PBS with proprietary stabilizer and <0.1% sodium azide
Gene Accession No.
P05532
Gene Symbols
KIT
Immunogen
IL-3-dependent mast cells derived from normal bone marrow.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2b κ
Applications
Flow Cytometry
Clone
2B8
Conjugate
APC-Cyanine7
Gene
KIT
Gene Alias
belly-spot; Bs; CD117; ckit; C-Kit; c-KIT gene1; c-kit protein; c-kit proto-oncogene protein; c-kit receptor; c-kit receptor tyrosine kinase; dominant spotting; Dominant white spotting; Fdc; Gsfsco1; Gsfsco5; Gsfsow3; KIT; kit oncogene; KIT proto-oncogene receptor tyrosine kinase; KIT proto-oncogene, receptor tyrosine kinase; mast cell growth factor receptor; mast/stem cell growth factor receptor; mast/stem cell growth factor receptor Kit; MGF; p145 c-kit; PBT; Piebald trait protein; protein kinase; proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; receptor tyrosine kinase c-kit; receptor tyrosine kinase type III; SCFR; SCO1; SCO5; Sl; soluble KIT variant 1; SOW3; spotted sterile male; Ssm; Steel Factor Receptor; Tr-kit; tyrosine kinase receptor; tyrosine kinase receptor c-KIT; tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; W
Host Species
Rat
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
16590
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Related Products
Description
- KIT (c-KIT) is a proto-oncogene and a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor)
- KIT was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit
- KIT together with its ligand regulates growth and activation of a variety of hemopoietic and non-hemopoietic cells
- Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism
- Recently, deregulation of the KIT receptor TK by the prevalent activation loop mutation D816V has served as a focal point in therapeutic strategies aimed at curbing neoplastic mast cell growth
- c-Kit is expressed in hematopoietic stem cells, germ cells, mast cells and gastrointestinal tract cajal cells
- Upon binding of its ligand stem cell factor (SCF), c-kit dimerizes, resulting in receptor activation and autophosphorylation of various tyrosine residues including tyrosine 703 located on the cytoplasmic domain of the receptor
- This modification allows docking of Grb2 and activation of the Ras/ERK signaling pathway
- SCF/c-kit can activate multiple downstream signaling pathways including PI3K, PLC-gamma and JAK/STAT
- c-kit receptor activation is essential for hematopoiesis, stem cell maintenance and gametogenesis.
Compare Similar Items
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Antigen: c-Kit
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with proprietary stabilizer and <0.1% sodium azide
Gene Accession No.: P05532
Gene Symbols: KIT
Immunogen: IL-3-dependent mast cells derived from normal bone marrow.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2b κ
Applications: Flow Cytometry
Clone: 2B8
Conjugate: APC-Cyanine7
Gene: KIT
Gene Alias: belly-spot; Bs; CD117; ckit; C-Kit; c-KIT gene1; c-kit protein; c-kit proto-oncogene protein; c-kit receptor; c-kit receptor tyrosine kinase; dominant spotting; Dominant white spotting; Fdc; Gsfsco1; Gsfsco5; Gsfsow3; KIT; kit oncogene; KIT proto-oncogene receptor tyrosine kinase; KIT proto-oncogene, receptor tyrosine kinase; mast cell growth factor receptor; mast/stem cell growth factor receptor; mast/stem cell growth factor receptor Kit; MGF; p145 c-kit; PBT; Piebald trait protein; protein kinase; proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; receptor tyrosine kinase c-kit; receptor tyrosine kinase type III; SCFR; SCO1; SCO5; Sl; soluble KIT variant 1; SOW3; spotted sterile male; Ssm; Steel Factor Receptor; Tr-kit; tyrosine kinase receptor; tyrosine kinase receptor c-KIT; tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; W
Host Species: Rat
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 16590
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Antigen:
c-Kit
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with proprietary stabilizer and <0.1% sodium azide
Gene Accession No.:
P05532
Gene Symbols:
KIT
Immunogen:
IL-3-dependent mast cells derived from normal bone marrow.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2b κ
Applications:
Flow Cytometry
Clone:
2B8
Conjugate:
APC-Cyanine7
Gene:
KIT
Gene Alias:
belly-spot; Bs; CD117; ckit; C-Kit; c-KIT gene1; c-kit protein; c-kit proto-oncogene protein; c-kit receptor; c-kit receptor tyrosine kinase; dominant spotting; Dominant white spotting; Fdc; Gsfsco1; Gsfsco5; Gsfsow3; KIT; kit oncogene; KIT proto-oncogene receptor tyrosine kinase; KIT proto-oncogene, receptor tyrosine kinase; mast cell growth factor receptor; mast/stem cell growth factor receptor; mast/stem cell growth factor receptor Kit; MGF; p145 c-kit; PBT; Piebald trait protein; protein kinase; proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; receptor tyrosine kinase c-kit; receptor tyrosine kinase type III; SCFR; SCO1; SCO5; Sl; soluble KIT variant 1; SOW3; spotted sterile male; Ssm; Steel Factor Receptor; Tr-kit; tyrosine kinase receptor; tyrosine kinase receptor c-KIT; tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; W
Host Species:
Rat
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
16590
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Antigen: Ly-6G/Ly-6C
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with proprietary stabilizer and <0.1% sodium azide
Gene Accession No.: P0CW02, P0CW03, P35461
Gene Symbols: Ly6c1, Ly6c2, Ly6g
Immunogen: Normal murine bone marrow cells
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2b κ
Applications: Flow Cytometry
Clone: RB6-8C5
Conjugate: APC-Cyanine7
Gene: Ly6g
Gene Alias: AA682074; AA959465; Gr1; Gr-1; Granulocyte Marker; Ly6c; Ly-6C; Ly-6C.2; Ly6c1; Ly-6C1; Ly6c2; Ly-6C2; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus C; lymphocyte antigen 6 complex, locus C1; lymphocyte antigen 6 complex, locus C2; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6C precursor (Ly-6C); lymphocyte antigen 6C1; Lymphocyte antigen 6C2; lymphocyte antigen 6G; Lymphocyte antigen Ly-6C; lymphocyte differentiation antigen; PML; PMN
Host Species: Rat
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 100041546, 17067, 546644
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Antigen:
Ly-6G/Ly-6C
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with proprietary stabilizer and <0.1% sodium azide
Gene Accession No.:
P0CW02, P0CW03, P35461
Gene Symbols:
Ly6c1, Ly6c2, Ly6g
Immunogen:
Normal murine bone marrow cells
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2b κ
Applications:
Flow Cytometry
Clone:
RB6-8C5
Conjugate:
APC-Cyanine7
Gene:
Ly6g
Gene Alias:
AA682074; AA959465; Gr1; Gr-1; Granulocyte Marker; Ly6c; Ly-6C; Ly-6C.2; Ly6c1; Ly-6C1; Ly6c2; Ly-6C2; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus C; lymphocyte antigen 6 complex, locus C1; lymphocyte antigen 6 complex, locus C2; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6C precursor (Ly-6C); lymphocyte antigen 6C1; Lymphocyte antigen 6C2; lymphocyte antigen 6G; Lymphocyte antigen Ly-6C; lymphocyte differentiation antigen; PML; PMN
Host Species:
Rat
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
100041546, 17067, 546644
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Antigen: ITGA2, CD49b
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with <0.1% sodium azide
Gene Accession No.: P17301
Gene Symbols: Itga2
Immunogen: Human CD49b from Human keratinocytes
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: HAS-4
Conjugate: PE
Gene: Itga2
Gene Alias: alpha 2 subunit of VLA-2 receptor; BDPLT9; BR; CD49 antigen-like family member B; CD49B; Collagen receptor; DX5; GPIa; HPA-5; human platelet alloantigen system 5; integrin alpha 2; integrin alpha-2; integrin subunit alpha 2; integrin, alpha 2; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); Itga2; platelet antigen Br; platelet glycoprotein GPIa; platelet membrane glycoprotein Ia; very late activation protein 2 receptor, alpha-2 subunit; VLA-2; VLA2 receptor; VLA-2 receptor, alpha 2 subunit; VLA-2 subunit alpha; VLAA2
Host Species: Mouse
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 3673
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Antigen:
ITGA2, CD49b
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with <0.1% sodium azide
Gene Accession No.:
P17301
Gene Symbols:
Itga2
Immunogen:
Human CD49b from Human keratinocytes
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
HAS-4
Conjugate:
PE
Gene:
Itga2
Gene Alias:
alpha 2 subunit of VLA-2 receptor; BDPLT9; BR; CD49 antigen-like family member B; CD49B; Collagen receptor; DX5; GPIa; HPA-5; human platelet alloantigen system 5; integrin alpha 2; integrin alpha-2; integrin subunit alpha 2; integrin, alpha 2; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); Itga2; platelet antigen Br; platelet glycoprotein GPIa; platelet membrane glycoprotein Ia; very late activation protein 2 receptor, alpha-2 subunit; VLA-2; VLA2 receptor; VLA-2 receptor, alpha 2 subunit; VLA-2 subunit alpha; VLAA2
Host Species:
Mouse
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
3673
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Antigen: VCAM-1, CD106 (VCAM-1)
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with <0.1% sodium azide
Gene Accession No.: P19320
Gene Symbols: VCAM1
Immunogen: human CD106
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Porcine
Product Type: Antibody
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: 1.G11B1
Conjugate: FITC
Gene: VCAM1
Gene Alias: adhesion molecule VCAM-1; CD106; CD106 antigen; DKFZp779G2333; INCAM100; INCAM-100; MGC99561; sCD106; soluble CD106; soluble VCAM 1; sVCAM 1; vascular cell adhesion molecule; vascular cell adhesion molecule 1; vascular cell adhesion molecule-1; vascular cell adhesion protein 1; V-CAM 1; Vcam1; Vcam-1; VCAM1B
Host Species: Mouse
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 396925, 7412
Content And Storage: 4° C, store in dark
Form: Liquid
Antigen:
VCAM-1, CD106 (VCAM-1)
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with <0.1% sodium azide
Gene Accession No.:
P19320
Gene Symbols:
VCAM1
Immunogen:
human CD106
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Porcine
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
1.G11B1
Conjugate:
FITC
Gene:
VCAM1
Gene Alias:
adhesion molecule VCAM-1; CD106; CD106 antigen; DKFZp779G2333; INCAM100; INCAM-100; MGC99561; sCD106; soluble CD106; soluble VCAM 1; sVCAM 1; vascular cell adhesion molecule; vascular cell adhesion molecule 1; vascular cell adhesion molecule-1; vascular cell adhesion protein 1; V-CAM 1; Vcam1; Vcam-1; VCAM1B
Host Species:
Mouse
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
396925, 7412
Content And Storage:
4° C, store in dark
Form:
Liquid