50-113-7092

c-Kit Monoclonal Antibody (104D2), FITC, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-113-7092-Each-of-1 In Stock ₹ 16,427.52

50-113-7092 - Each of 1

₹ 16,427.52

In Stock

Quantity

1

Base Price: ₹ 16,427.52

GST (18%): ₹ 2,956.954

Total Price: ₹ 19,384.474

Antigen

c-Kit

Classification

Monoclonal

Conjugate

FITC

Gene

KIT

Gene Alias

belly-spot; Bs; CD117; ckit; C-Kit; c-KIT gene1; c-kit protein; c-kit proto-oncogene protein; c-kit receptor; c-kit receptor tyrosine kinase; dominant spotting; Dominant white spotting; Fdc; Gsfsco1; Gsfsco5; Gsfsow3; KIT; kit oncogene; KIT proto-oncogene receptor tyrosine kinase; KIT proto-oncogene, receptor tyrosine kinase; mast cell growth factor receptor; mast/stem cell growth factor receptor; mast/stem cell growth factor receptor Kit; MGF; p145 c-kit; PBT; Piebald trait protein; protein kinase; proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; receptor tyrosine kinase c-kit; receptor tyrosine kinase type III; SCFR; SCO1; SCO5; Sl; soluble KIT variant 1; SOW3; spotted sterile male; Ssm; Steel Factor Receptor; Tr-kit; tyrosine kinase receptor; tyrosine kinase receptor c-KIT; tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; W

Host Species

Mouse

Purification Method

Size-exclusion chromatography

Regulatory Status

RUO

Gene ID (Entrez)

280832, 3815

Content And Storage

4° C, store in dark

Form

Liquid

Applications

Flow Cytometry

Clone

104D2

Formulation

PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.

P10721, P43481

Gene Symbols

KIT

Immunogen

MOLM-1 megakaryocytic cells

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Bovine, Human, Non-human Primate

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • KIT (c-KIT) is a proto-oncogene and a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor)
  • KIT was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit
  • KIT together with its ligand regulates growth and activation of a variety of hemopoietic and non-hemopoietic cells
  • Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism
  • Recently, deregulation of the KIT receptor TK by the prevalent activation loop mutation D816V has served as a focal point in therapeutic strategies aimed at curbing neoplastic mast cell growth
  • c-Kit is expressed in hematopoietic stem cells, germ cells, mast cells and gastrointestinal tract cajal cells
  • Upon binding of its ligand stem cell factor (SCF), c-kit dimerizes, resulting in receptor activation and autophosphorylation of various tyrosine residues including tyrosine 703 located on the cytoplasmic domain of the receptor
  • This modification allows docking of Grb2 and activation of the Ras/ERK signaling pathway
  • SCF/c-kit can activate multiple downstream signaling pathways including PI3K, PLC-gamma and JAK/STAT
  • c-kit receptor activation is essential for hematopoiesis, stem cell maintenance and gametogenesis.

Compare Similar Items

Show Difference

Img

Invitrogen

50-113-7092

--


Antigen:
c-Kit

Classification:
Monoclonal

Conjugate:
FITC

Gene:
KIT

Gene Alias:
belly-spot; Bs; CD117; ckit; C-Kit; c-KIT gene1; c-kit protein; c-kit proto-oncogene protein; c-kit receptor; c-kit receptor tyrosine kinase; dominant spotting; Dominant white spotting; Fdc; Gsfsco1; Gsfsco5; Gsfsow3; KIT; kit oncogene; KIT proto-oncogene receptor tyrosine kinase; KIT proto-oncogene, receptor tyrosine kinase; mast cell growth factor receptor; mast/stem cell growth factor receptor; mast/stem cell growth factor receptor Kit; MGF; p145 c-kit; PBT; Piebald trait protein; protein kinase; proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; receptor tyrosine kinase c-kit; receptor tyrosine kinase type III; SCFR; SCO1; SCO5; Sl; soluble KIT variant 1; SOW3; spotted sterile male; Ssm; Steel Factor Receptor; Tr-kit; tyrosine kinase receptor; tyrosine kinase receptor c-KIT; tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; W

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
280832, 3815

Content And Storage:
4° C, store in dark

Form:
Liquid

Applications:
Flow Cytometry

Clone:
104D2

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P10721, P43481

Gene Symbols:
KIT

Immunogen:
MOLM-1 megakaryocytic cells

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Invitrogen

50-113-7096

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Antigen:
CD84

Classification:
Monoclonal

Conjugate:
FITC

Gene:
CD84

Gene Alias:
A130013D22Rik; CD84; CD84 antigen; CD84 antigen (leukocyte antigen); CD84 molecule; CDw84; cell surface antigen MAX.3; DKFZp781E2378; hCD84; Hly9-beta; leucocyte differentiation antigen CD84; leukocyte antigen CD84; leukocyte differentiation antigen CD84; LY9B; mCD84; RGD1564553; Signaling lymphocytic activation molecule 5; SLAM family member 5; SLAMF5

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8832

Content And Storage:
4° C, store in dark

Form:
Liquid

Applications:
Flow Cytometry

Clone:
CD84.1.21

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
Q9UIB8

Gene Symbols:
CD84

Immunogen:
CD84-transfected 30019 cell line

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Invitrogen

50-113-7097

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Antigen:
Bcl-2

Classification:
Monoclonal

Conjugate:
FITC

Gene:
Bcl2

Gene Alias:
apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
596

Content And Storage:
4° C, store in dark

Form:
Liquid

Applications:
Flow Cytometry

Clone:
Bcl2/100

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P10415

Gene Symbols:
Bcl2

Immunogen:
Synthetic peptide corresponding to the amino acids 41-54 of human Bcl2

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Optimize Technologies

50-113-710

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