50-121-32

CX3CR1 Monoclonal Antibody (2A9-1), Biotin, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-121-32-Each-of-1 In Stock ₹ 30,544.92

50-121-32 - Each of 1

₹ 30,544.92

In Stock

Quantity

1

Base Price: ₹ 30,544.92

GST (18%): ₹ 5,498.086

Total Price: ₹ 36,043.006

Antigen

CX3CR1

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P49238

Gene Symbols

CX3CR1

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1524

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

2A9-1

Conjugate

Biotin

Gene

CX3CR1

Gene Alias

Beta chemokine receptor-like 1; CCRL1; chemokine (C-C) receptor-like 1; chemokine (C-X3-C motif) receptor 1; chemokine (C-X3-C) receptor 1; CMKBRL1; CMK-BRL1; CMK-BRL-1; CMKDR1; Cx3c; CX3C chemokine receptor 1; C-X3-C CKR-1; C-X3-C motif chemokine receptor 1; Cx3cr1; Fractalkine receptor; G protein-coupled receptor 13; GPR13; G-protein coupled receptor 13; GPRV28; RBS11; Scyd1; V28

Host Species

Rat

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b κ

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Description

  • Description: This 2A9-1 monoclonal antibody reacts with human CX3CR1, which is the receptor for fractalkine, a transmembrane chemokine of the CX3C family
  • CX3CR1 is a seven transmembrane G protein-coupled receptor expressed on CD16+ NK cells, T cells (e.g
  • CD8+, CD4+, and gamma/delta), and monocytes
  • In non-immune cells, CX3CR1 has been found on osteoclast precursors and microglia
  • Little to no CX3CR1 surface expression can be detected on B cells and granulocytes
  • Together, fractalkine and its receptor mediate cell-cell adhesion and chemotaxis of NK cells, T cells, and monocytes
  • The expression of CX3CR1 has also been correlated with high levels of intracellular perforin and granzyme B
  • Applications Reported: This 2A9-1 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This 2A9-1 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells
  • This can be used at less than or equal to 0.25 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Filtration: 0.2 μm post-manufacturing filtered
  • CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection
  • The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively
  • The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1
  • Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine
  • CX3CR1 mediates leukocyte migration an d adhesion
  • CX3CR1 is expressed in a variety of human tissues and cell lines.

Compare Similar Items

Show Difference

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Invitrogen

50-121-32

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Antigen:
CX3CR1

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P49238

Gene Symbols:
CX3CR1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1524

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
2A9-1

Conjugate:
Biotin

Gene:
CX3CR1

Gene Alias:
Beta chemokine receptor-like 1; CCRL1; chemokine (C-C) receptor-like 1; chemokine (C-X3-C motif) receptor 1; chemokine (C-X3-C) receptor 1; CMKBRL1; CMK-BRL1; CMK-BRL-1; CMKDR1; Cx3c; CX3C chemokine receptor 1; C-X3-C CKR-1; C-X3-C motif chemokine receptor 1; Cx3cr1; Fractalkine receptor; G protein-coupled receptor 13; GPR13; G-protein coupled receptor 13; GPRV28; RBS11; Scyd1; V28

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b κ

Img

Invitrogen

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Antigen:
DR3

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q93038

Gene Symbols:
TNFRSF25

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8718

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
JD3

Conjugate:
Biotin

Gene:
TNFRSF25

Gene Alias:
APO3; APO-3; apoptosis inducing receptor; apoptosis-inducing receptor AIR; Apoptosis-mediating receptor DR3; apoptosis-mediating receptor TRAMP; DDR3; death domain receptor 3 soluble form; Death receptor 3; death receptor beta; DR3; LARD; lymphocyte-associated receptor of death; Protein WSL; Protein WSL-1; RP4-650H14.2; TNF receptor superfamily member 25; TNFRSF12; TNFRSF25; TR3; TRAMP; tumor necrosis factor receptor superfamily member 25; tumor necrosis factor receptor superfamily, member 12; tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein); tumor necrosis factor receptor superfamily, member 25; UNQ455/PRO779; Wsl; WSL1; WSL-1; WSL-LR

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

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Hampton Research

50-121-4

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