25-195-642

CD195 (CCR5) Monoclonal Antibody (NP-6G4), PE-Cyanine7, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 25-195-642-Each-of-1 In Stock ₹ 36,790.80

25-195-642 - Each of 1

₹ 36,790.80

In Stock

Quantity

1

Base Price: ₹ 36,790.80

GST (18%): ₹ 6,622.344

Total Price: ₹ 43,413.144

Antigen

CD195 (CCR5)

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

P51681

Gene Symbols

CCR5

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1234

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

NP-6G4

Conjugate

PE-Cyanine7

Gene

CCR5

Gene Alias

AM4-7; C-C chemokine receptor type 5; C-C CKR-5; C-C motif chemokine receptor 5 (gene/pseudogene); C-C motif chemokine receptor 5 A159A; CCCKR5; CC-CKR-5; Ccr5; CCR-5; CD195; CD195 antigen; chemokine (C-C motif) receptor 5; chemokine (C-C) receptor 5; chemokine receptor CCR5; chemr13; CKR5; CKR-5; Cmkbr5; HIV-1 fusion coreceptor; IDDM22; MIP-1 alpha receptor

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • The NP-6G4 MAb reacts with human CD195 (CCR5), an approximately 45 kDa member of the G protein-coupled receptor (GPCR) superfamily that binds chemokines including MIP-1a, MIP-1b and RANTES
  • Human CCR5 is expressed on resting T cells with a memory/effector phenotype, monocytes, macrophages and immature dendritic cells
  • CCR5 functions as a receptor to direct the chemotaxis of lymphocytes, and is the primary co-receptor for macrophage-tropic Human Immunodeficiency Virus Type 1 (HIV-1), which binds CCR5 through gp120
  • Human immunodeficiency virus (HIV) and related virus require coreceptors, in addition to CD4, to infect target cells
  • Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV coreceptors
  • Among them, CCR5 (CC-CKR-5) is a principal coreceptor for macrophage- and dual-tropic HIV-1 strains fusion and entry of human white blood cells
  • CCR5 is required for the infection by HIV-1, HIV-2, and SIV
  • The beta-chemokines RANTES, MIP-alpha and MIP-beta are the ligands for CCR5 and prevent infection by M-tropic HIV-1
  • CCR5 associates with the surface CD4-gp120 of HIV complex and leads to membrane fusion and virus entry of target cells
  • The amino-terminal domain and the extracellular loops of CCR5 serve as HIV biding sites
  • CCR5 messenger RNA is expressed in lymphoid organs and monocytes.

Compare Similar Items

Show Difference

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Invitrogen

25-195-642

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Antigen:
CD195 (CCR5)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P51681

Gene Symbols:
CCR5

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1234

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
NP-6G4

Conjugate:
PE-Cyanine7

Gene:
CCR5

Gene Alias:
AM4-7; C-C chemokine receptor type 5; C-C CKR-5; C-C motif chemokine receptor 5 (gene/pseudogene); C-C motif chemokine receptor 5 A159A; CCCKR5; CC-CKR-5; Ccr5; CCR-5; CD195; CD195 antigen; chemokine (C-C motif) receptor 5; chemokine (C-C) receptor 5; chemokine receptor CCR5; chemr13; CKR5; CKR-5; Cmkbr5; HIV-1 fusion coreceptor; IDDM22; MIP-1 alpha receptor

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

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Invitrogen

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Antigen:
CD196 (CCR6)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P51684

Gene Symbols:
CCR6

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1235

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
R6H1

Conjugate:
PE-Cyanine7

Gene:
CCR6

Gene Alias:
BN-1; CC chemokine receptor 6; C-C chemokine receptor type 6; C-C CKR-6; C-C motif chemokine receptor 6; CC-CKR-6; CCR6; CCR-6; CD196; chemokine (C-C motif) receptor 6; chemokine (C-C) receptor 6; chemokine receptor-like 3; CKR6; CKRL3; CKR-L3; Cmkbr6; DCR2; DRY6; DRY-6; G protein-coupled receptor 29; GPR29; GPRCY4; GPR-CY4; G-protein coupled receptor 29; KY411; LARC receptor; seven-transmembrane receptor, lymphocyte, 22; STRL22

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

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Fischer Scientific

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Antigen:
CD197 (CCR7)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P32248

Gene Symbols:
Ccr7

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1236

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
3D12

Conjugate:
PE-Cyanine7

Gene:
Ccr7

Gene Alias:
BLR2; Bukitt's lymphoma receptor 2; CC chemokine receptor 7; C-C chemokine receptor type 7; C-C CKR-7; C-C motif chemokine receptor 7; CC-CKR-7; CCR7; CCR-7; CD197; CDw197; chemokine (C-C motif) receptor 7; chemokine (C-C) receptor 7; Cmkbr7; EBI1; Ebi1h; EBV-induced G protein-coupled receptor 1; EBV-induced G-protein coupled receptor 1; Epstein-Barr virus induced gene 1; Epstein-Barr virus-induced G-protein coupled receptor 1; EVI1; lymphocyte-specific G protein-coupled peptide receptor; MIP-3 beta receptor

Host Species:
Rat

Quantity:
25 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ

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Antigen:
CD200R3

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q5UKY4

Gene Symbols:
CD200R3

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
74603

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
Ba13

Conjugate:
PE-Cyanine7

Gene:
CD200R3

Gene Alias:
4733401I18Rik; 4833409J19Rik; AI505817; BB106877; CD200 cell surface glycoprotein receptor 3; CD200 cell surface glycoprotein receptor-like 3; CD200 cell surface glycoprotein receptor-like b; CD200 receptor 3; CD200 receptor-like 3; Cd200r3; CD200RLb; cell surface glycoprotein CD200 receptor 3; Cell surface glycoprotein OX2 receptor 3; mCD200RLb

Host Species:
Rat

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ