50-132-06

Nestin Monoclonal Antibody (Rat-401 (Rat401 (4D4))), eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-132-06-Each-of-1 In Stock ₹ 32,512.80

50-132-06 - Each of 1

₹ 32,512.80

In Stock

Quantity

1

Base Price: ₹ 32,512.80

GST (18%): ₹ 5,852.304

Total Price: ₹ 38,365.104

Antigen

Nestin

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P21263, Q6P5H2

Gene Symbols

Nes

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18008, 25491

Content And Storage

4° C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone

Rat-401 (Rat401 (4D4))

Conjugate

Unconjugated

Gene

Nes

Gene Alias

AA166324; C78523; ESTM46; FLJ21841; intermediate filament protein; Nbla00170; Nes; Nestin

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse, Rat

Product Type

Antibody

Isotype

IgG1

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Description

  • Description: The monoclonal antibody Rat-401 recognizes mouse and rat nestin, a Class VI intermediate filament protein (>170 kDa) primarily expressed in neuroepithelial stem cells
  • Upon neural differentiation, expression is down-regulated and within the adult nervous system is limited to progenitor cells in the cortical subventricular zone, the hippocampal dentate gyrus, dorsal root ganglia satellite cells, and a subpopulation of Schwann cells
  • Nestin expression is also present in other progenitor cell populations such as pancreatic islet, angiogenic endothelial cells, and bone marrow mesenchymal stem cells
  • Nestin filaments require vimentin and desmin for assembly into heterodimers and polymers
  • Upon differentiation, Nestin-containing filaments are replaced by cell type specific intermediate filament proteins, such as GFAP
  • Applications Reported: This Rat-401 (Rat401 (4D4)) antibody has been reported for use in western blotting, immunohistochemical staining of frozen tissue sections, immunohistochemical staining of formalin-fixed paraffin embedded tissue sections, and immunocytochemistry
  • Applications Tested: This Rat-401 antibody has been tested by immunofluorescent staining of paraformaldehyde fixed and permeabilized cells and by immunohistochemistry of formalin-fixed paraffin embedded mouse tissue using low or high pH antigen retrieval
  • This can be used at less than or equal to 10 μg/mL
  • Nestin is a Class VI intermediate filament abundantly produced in the developing central nervous system (CNS) and in early embryonic neuroepithelial stem cells
  • Nestin has been widely used as a predominant marker for stem/progenitor cells, glioma cells, and tumor endothelial cells
  • Also, Nestin is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumors
  • Highly specific antibodies to human Nestin can aid in characterizing progenitor cells differentiating into distinct lineages, in enhancing the therapeutic potential of human neural stem/progenitor cells in the treatment of CNS diseases or injury, and in identifying neuroepithelial tumor cells
  • Nestin expression has been observed in pancreatic hematopoietic stem cell populations, and is considered a novel angiogenesis marker of proliferating endothelial cells in colorectal cancer tissue.

Compare Similar Items

Show Difference

Img

Fischer Scientific

50-132-06

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Antigen:
Nestin

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P21263, Q6P5H2

Gene Symbols:
Nes

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18008, 25491

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
Rat-401 (Rat401 (4D4))

Conjugate:
Unconjugated

Gene:
Nes

Gene Alias:
AA166324; C78523; ESTM46; FLJ21841; intermediate filament protein; Nbla00170; Nes; Nestin

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Img

Invitrogen

50-132-08

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Antigen:
FCRLA (FREB)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q7L513

Gene Symbols:
FCRLA

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84824

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry

Clone:
N28.1

Conjugate:
Unconjugated

Gene:
FCRLA

Gene Alias:
Fc receptor homolog expressed in B cells (FREB); fc receptor homolog expressed in B-cells; Fc receptor like A; Fc receptor related protein X; Fc receptor-like A; Fc receptor-like and mucin-like 1; fc receptor-like and mucin-like protein 1; Fc receptor-like protein; fc receptor-related protein X; FCRL; FCRL1; FCRLA; FCRLb; FCRLc1; FCRLc2; FCRLd; FCRLe; FCRLM1; FCRLX; FCRX; FREB; UNQ291/PRO329

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Fischer Scientific

50-132-21

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Antigen:
Nod2

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q8K3Z0

Gene Symbols:
NOD2

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
257632

Content And Storage:
4° C

Form:
Liquid

Applications:
Western Blot

Clone:
26mNOD2

Conjugate:
Unconjugated

Gene:
NOD2

Gene Alias:
ACUG; BLAU; CARD15; caspase recruitment domain family, member 15; caspase recruitment domain protein 15; caspase recruitment domain-containing protein 15; CD; CLR16.3; F830032C23Rik; IBD1; Inflammatory bowel disease protein 1; NLR family, CARD domain containing 2; Nlrc2; NOD 2; NOD2; NOD-2; NOD2 protein; NOD2B; NOD-like receptor C2; nucleotide binding oligomerization domain containing 2; nucleotide-binding oligomerization domain 2; nucleotide-binding oligomerization domain containing 2; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 2; nucleotide-binding oligomerization domain-containing protein 2; PSORAS1

Host Species:
Rat

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Fischer Scientific

50-132-22

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Antigen:
Nod2

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q8K3Z0

Gene Symbols:
NOD2

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
257632

Content And Storage:
4° C

Form:
Liquid

Applications:
Western Blot

Clone:
26mNOD2

Conjugate:
Unconjugated

Gene:
NOD2

Gene Alias:
ACUG; BLAU; CARD15; caspase recruitment domain family, member 15; caspase recruitment domain protein 15; caspase recruitment domain-containing protein 15; CD; CLR16.3; F830032C23Rik; IBD1; Inflammatory bowel disease protein 1; NLR family, CARD domain containing 2; Nlrc2; NOD 2; NOD2; NOD-2; NOD2 protein; NOD2B; NOD-like receptor C2; nucleotide binding oligomerization domain containing 2; nucleotide-binding oligomerization domain 2; nucleotide-binding oligomerization domain containing 2; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 2; nucleotide-binding oligomerization domain-containing protein 2; PSORAS1

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ