50-133-73
Blimp-1 Monoclonal Antibody (6D3), eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-133-73-Each-of-1 | In Stock | ₹ 35,935.20 |
50-133-73 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,935.20
GST (18%): ₹ 6,468.336
Total Price: ₹ 42,403.536
Antigen
Blimp-1
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
O75626, Q60636
Gene Symbols
PRDM1
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12142, 639
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone
6D3
Conjugate
Unconjugated
Gene
PRDM1
Gene Alias
B lymphocyte-induced maturation protein 1; b2b1765Clo; Beta-interferon gene positive regulatory domain I-binding factor; beta-interferon gene positive-regulatory domain I binding factor; BLIMP 1; Blimp1; BLIMP-1; B-lymphocyte-induced maturation protein 1; MGC118922; MGC118923; MGC118924; MGC118925; OTTHUMP00000016918; OTTHUMP00000202173; Positive regulatory domain I-binding factor 1; PR domain 1; PR domain containing 1, with ZNF domain; PR domain zinc finger protein 1; PR domain-containing protein 1; PR/SET domain 1; PRDI BF1; PRDI-BF1; PRDI-binding factor-1; Prdm1; RP1-134E15.1; ZNFPR1A1
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG2a
Related Products
Description
- Description: This 6D3 monoclonal antibody reacts with B lymphocyte-induced maturation protein-1 (Blimp-1), a transcriptional repressor expressed in B and T cells
- This approximately 90-kDa protein contains five consecutive Kruppel-like zinc finger domains by which it binds DNA
- In B cells, Blimp-1 promotes terminal differentiation into antibody-secreting plasma cells during a primary immune response
- In addition, Blimp-1 has been implicated in germinal center formation in response to T-dependent and T-independent antigens, as well as in some diffuse large B cell lymphomas
- Expressed in CD4+ and CD8+ effector/memory T cells and FoxP3+ regulatory T cells, reports have suggested possible roles for Blimp-1 in T cell homeostasis and suppression of IL-2 production
- Moreover, by suppressing Th1 differentiation, Blimp-1 plays a role in T helper cell differentiation
- Finally, Blimp-1 has been demonstrated to play a significant role in the terminal differentiation of effector and effector memory CD8+ T cells during viral infection
- Applications Reported: This 6D3 antibody has been reported for use in immunoblotting (WB) and immunohistology staining of paraffin-embedded tissue sections
- Applications Tested: This 6D3 antibody has been tested by western blot of reduced A20 cell lysates
- For western blottiing, this antibody can be used at 1-10 μg/mL
- Moreover, this antibody was tested by immunohistochemistry of formalin-fixed paraffin embedded human tonsil tissue
- Blimp-1 (B lymphocyte maturation protein-1) is a nuclear protein with five zinc fingers in its carboxy terminus
- It is a transcriptional repressor that is both required and sufficient to trigger terminal differentiation of B lymphocytes and monocyte/macrophages
- Blimp-1 is expressed in, and may be required for terminally differentiated epithelial cells, retinal neurons and other lineage cells
- It has also been implicated in the repression of beta-interferon (IFN-beta) and c-myc gene expression.
Compare Similar Items
Show Difference
Antigen: Blimp-1
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: O75626, Q60636
Gene Symbols: PRDM1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12142, 639
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone: 6D3
Conjugate: Unconjugated
Gene: PRDM1
Gene Alias: B lymphocyte-induced maturation protein 1; b2b1765Clo; Beta-interferon gene positive regulatory domain I-binding factor; beta-interferon gene positive-regulatory domain I binding factor; BLIMP 1; Blimp1; BLIMP-1; B-lymphocyte-induced maturation protein 1; MGC118922; MGC118923; MGC118924; MGC118925; OTTHUMP00000016918; OTTHUMP00000202173; Positive regulatory domain I-binding factor 1; PR domain 1; PR domain containing 1, with ZNF domain; PR domain zinc finger protein 1; PR domain-containing protein 1; PR/SET domain 1; PRDI BF1; PRDI-BF1; PRDI-binding factor-1; Prdm1; RP1-134E15.1; ZNFPR1A1
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG2a
Antigen:
Blimp-1
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
O75626, Q60636
Gene Symbols:
PRDM1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12142, 639
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone:
6D3
Conjugate:
Unconjugated
Gene:
PRDM1
Gene Alias:
B lymphocyte-induced maturation protein 1; b2b1765Clo; Beta-interferon gene positive regulatory domain I-binding factor; beta-interferon gene positive-regulatory domain I binding factor; BLIMP 1; Blimp1; BLIMP-1; B-lymphocyte-induced maturation protein 1; MGC118922; MGC118923; MGC118924; MGC118925; OTTHUMP00000016918; OTTHUMP00000202173; Positive regulatory domain I-binding factor 1; PR domain 1; PR domain containing 1, with ZNF domain; PR domain zinc finger protein 1; PR domain-containing protein 1; PR/SET domain 1; PRDI BF1; PRDI-BF1; PRDI-binding factor-1; Prdm1; RP1-134E15.1; ZNFPR1A1
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG2a
Antigen: Nur77
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P12813
Gene Symbols: NR4A1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15370
Content And Storage: 4° C
Form: Liquid
Applications: Western Blot
Clone: 12.14
Conjugate: Unconjugated
Gene: NR4A1
Gene Alias: early response protein NAK1; Gfrp; GFRP1; growth factor-inducible nuclear protein N10; Hbr1; Hbr-1; Hmr; hormone receptor; immediate early gene transcription factor NGFI-B; MGC9485; N10; NAK1; NAK-1; nerve growth factor IB nuclear receptor variant 1; nerve growth factor induced protein I-B; nerve growth factor-induced protein I-B; Ngfib; NGFI-B; NP10; Nr4a1; Nuclear hormone receptor NUR/77; nuclear protein N10; Nuclear receptor subfamily 4 group A member 1; nuclear receptor subfamily 4, group A, member 1; NUR77; Orphan nuclear receptor HMR; orphan nuclear receptor TR3; Orphan receptor tr3; ST-59; steroid receptor TR3; testicular receptor 3; TIS1; TR3; TR3 orphan receptor
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
Nur77
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P12813
Gene Symbols:
NR4A1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15370
Content And Storage:
4° C
Form:
Liquid
Applications:
Western Blot
Clone:
12.14
Conjugate:
Unconjugated
Gene:
NR4A1
Gene Alias:
early response protein NAK1; Gfrp; GFRP1; growth factor-inducible nuclear protein N10; Hbr1; Hbr-1; Hmr; hormone receptor; immediate early gene transcription factor NGFI-B; MGC9485; N10; NAK1; NAK-1; nerve growth factor IB nuclear receptor variant 1; nerve growth factor induced protein I-B; nerve growth factor-induced protein I-B; Ngfib; NGFI-B; NP10; Nr4a1; Nuclear hormone receptor NUR/77; nuclear protein N10; Nuclear receptor subfamily 4 group A member 1; nuclear receptor subfamily 4, group A, member 1; NUR77; Orphan nuclear receptor HMR; orphan nuclear receptor TR3; Orphan receptor tr3; ST-59; steroid receptor TR3; testicular receptor 3; TIS1; TR3; TR3 orphan receptor
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD49b (Integrin alpha 2)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q62469
Gene Symbols: Itga2
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16398
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry
Clone: DX5
Conjugate: Unconjugated
Gene: Itga2
Gene Alias: alpha 2 subunit of VLA-2 receptor; BDPLT9; BR; CD49 antigen-like family member B; CD49B; Collagen receptor; DX5; GPIa; HPA-5; human platelet alloantigen system 5; integrin alpha 2; integrin alpha-2; integrin subunit alpha 2; integrin, alpha 2; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); Itga2; platelet antigen Br; platelet glycoprotein GPIa; platelet membrane glycoprotein Ia; very late activation protein 2 receptor, alpha-2 subunit; VLA-2; VLA2 receptor; VLA-2 receptor, alpha 2 subunit; VLA-2 subunit alpha; VLAA2
Host Species: Rat
Quantity: 500 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgM κ
Antigen:
CD49b (Integrin alpha 2)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q62469
Gene Symbols:
Itga2
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16398
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
DX5
Conjugate:
Unconjugated
Gene:
Itga2
Gene Alias:
alpha 2 subunit of VLA-2 receptor; BDPLT9; BR; CD49 antigen-like family member B; CD49B; Collagen receptor; DX5; GPIa; HPA-5; human platelet alloantigen system 5; integrin alpha 2; integrin alpha-2; integrin subunit alpha 2; integrin, alpha 2; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); Itga2; platelet antigen Br; platelet glycoprotein GPIa; platelet membrane glycoprotein Ia; very late activation protein 2 receptor, alpha-2 subunit; VLA-2; VLA2 receptor; VLA-2 receptor, alpha 2 subunit; VLA-2 subunit alpha; VLAA2
Host Species:
Rat
Quantity:
500 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgM κ
Antigen: B7-H4
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q7TSP5
Gene Symbols: Vtcn1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 242122
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry
Clone: 188
Conjugate: Unconjugated
Gene: Vtcn1
Gene Alias: B7 family member, H4; B7 homolog 4; B7 superfamily member 1; B7h.5; B7H4; B7-H4; B7s1; B7x; BC032925; EMBL:AAH95842.1}; FLJ22418; immune costimulatory protein B7-H4; PRO1291; Protein B7S1; RGD1311204; RP11-229A19.4; t cell costimulatory molecule B7x; T-cell costimulatory molecule B7x; UNQ659/PRO1291; VCTN1; V-set domain containing T cell activation inhibitor 1; V-set domain containing T-cell activation inhibitor 1; V-set domain-containing T-cell activation inhibitor 1; Vtcn1; vtcn1 {ECO:0000312
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
B7-H4
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q7TSP5
Gene Symbols:
Vtcn1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
242122
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
188
Conjugate:
Unconjugated
Gene:
Vtcn1
Gene Alias:
B7 family member, H4; B7 homolog 4; B7 superfamily member 1; B7h.5; B7H4; B7-H4; B7s1; B7x; BC032925; EMBL:AAH95842.1}; FLJ22418; immune costimulatory protein B7-H4; PRO1291; Protein B7S1; RGD1311204; RP11-229A19.4; t cell costimulatory molecule B7x; T-cell costimulatory molecule B7x; UNQ659/PRO1291; VCTN1; V-set domain containing T cell activation inhibitor 1; V-set domain containing T-cell activation inhibitor 1; V-set domain-containing T-cell activation inhibitor 1; Vtcn1; vtcn1 {ECO:0000312
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2b κ