50-155-8713
MYPT1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-155-8713-Each-of-1 | In Stock | ₹ 41,863.65 |
50-155-8713 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,863.65
GST (18%): ₹ 7,535.457
Total Price: ₹ 49,399.107
Antigen
MYPT1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PPP1R12A
Gene Alias
myosin phosphatase target subunit 1; myosin phosphatase, target subunit 1; myosin phosphatase-targeting subunit 1; protein phosphatase 1 regulatory subunit 12A
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4659
Content And Storage
4° C
Form
Liquid
Applications
Immunoprecipitation, Western Blot
Concentration
1 mg/ml
Formulation
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.
O14974
Gene Symbols
PPP1R12A
Immunogen
Between 400 and 450
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase
- Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho
- The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells
- The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC
- Rho-associated kinase (Rho-kinase), which is activated by GTP
- RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase
- Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosphorylation of MBS and MLC
- Thus, Rho appears to inhibit myosin phosphatase through the action of Rho-kinase
- Several transcript variants encoding different isoforms have been found for this gene.
Compare Similar Items
Show Difference
Antigen: MYPT1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PPP1R12A
Gene Alias: myosin phosphatase target subunit 1; myosin phosphatase, target subunit 1; myosin phosphatase-targeting subunit 1; protein phosphatase 1 regulatory subunit 12A
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4659
Content And Storage: 4° C
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: O14974
Gene Symbols: PPP1R12A
Immunogen: Between 400 and 450
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MYPT1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PPP1R12A
Gene Alias:
myosin phosphatase target subunit 1; myosin phosphatase, target subunit 1; myosin phosphatase-targeting subunit 1; protein phosphatase 1 regulatory subunit 12A
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4659
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
O14974
Gene Symbols:
PPP1R12A
Immunogen:
Between 400 and 450
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MYPT1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PPP1R12A
Gene Alias: myosin phosphatase target subunit 1; myosin phosphatase, target subunit 1; myosin phosphatase-targeting subunit 1; protein phosphatase 1 regulatory subunit 12A
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4659
Content And Storage: 4° C
Form: Liquid
Applications: Western Blot
Concentration: __
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: O14974
Gene Symbols: PPP1R12A
Immunogen: Between 400 and 450
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MYPT1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PPP1R12A
Gene Alias:
myosin phosphatase target subunit 1; myosin phosphatase, target subunit 1; myosin phosphatase-targeting subunit 1; protein phosphatase 1 regulatory subunit 12A
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4659
Content And Storage:
4° C
Form:
Liquid
Applications:
Western Blot
Concentration:
__
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
O14974
Gene Symbols:
PPP1R12A
Immunogen:
Between 400 and 450
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MYPT1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PPP1R12A
Gene Alias: myosin phosphatase target subunit 1; myosin phosphatase, target subunit 1; myosin phosphatase-targeting subunit 1; protein phosphatase 1 regulatory subunit 12A
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4659
Content And Storage: 4° C
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: 0.2 mg/ml
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: O14974
Gene Symbols: PPP1R12A
Immunogen: Between 800 and 850
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MYPT1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PPP1R12A
Gene Alias:
myosin phosphatase target subunit 1; myosin phosphatase, target subunit 1; myosin phosphatase-targeting subunit 1; protein phosphatase 1 regulatory subunit 12A
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4659
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
0.2 mg/ml
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
O14974
Gene Symbols:
PPP1R12A
Immunogen:
Between 800 and 850
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MYPT1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PPP1R12A
Gene Alias: myosin phosphatase target subunit 1; myosin phosphatase, target subunit 1; myosin phosphatase-targeting subunit 1; protein phosphatase 1 regulatory subunit 12A
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4659
Content And Storage: 4° C
Form: Liquid
Applications: Western Blot
Concentration: __
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: O14974
Gene Symbols: PPP1R12A
Immunogen: Between 800 and 850
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MYPT1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PPP1R12A
Gene Alias:
myosin phosphatase target subunit 1; myosin phosphatase, target subunit 1; myosin phosphatase-targeting subunit 1; protein phosphatase 1 regulatory subunit 12A
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4659
Content And Storage:
4° C
Form:
Liquid
Applications:
Western Blot
Concentration:
__
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
O14974
Gene Symbols:
PPP1R12A
Immunogen:
Between 800 and 850
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG