50-155-8718

MYPT1 Polyclonal Antibody, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-155-8718-Each-of-1 In Stock ₹ 11,905.67

50-155-8718 - Each of 1

₹ 11,905.67

In Stock

Quantity

1

Base Price: ₹ 11,905.67

GST (18%): ₹ 2,143.021

Total Price: ₹ 14,048.691

Antigen

MYPT1

Classification

Polyclonal

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.

O14974

Gene Symbols

PPP1R12A

Immunogen

Between 800 and 850

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Conjugate

Unconjugated

Gene

PPP1R12A

Gene Alias

myosin phosphatase target subunit 1; myosin phosphatase, target subunit 1; myosin phosphatase-targeting subunit 1; protein phosphatase 1 regulatory subunit 12A

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4659

Content And Storage

4° C

Form

Liquid

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase
  • Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho
  • The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells
  • The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC
  • Rho-associated kinase (Rho-kinase), which is activated by GTP
  • RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase
  • Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosphorylation of MBS and MLC
  • Thus, Rho appears to inhibit myosin phosphatase through the action of Rho-kinase
  • Several transcript variants encoding different isoforms have been found for this gene.

Compare Similar Items

Show Difference

Img

Bethyl Laboratories, Inc

50-155-8718

--


Antigen:
MYPT1

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
O14974

Gene Symbols:
PPP1R12A

Immunogen:
Between 800 and 850

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
PPP1R12A

Gene Alias:
myosin phosphatase target subunit 1; myosin phosphatase, target subunit 1; myosin phosphatase-targeting subunit 1; protein phosphatase 1 regulatory subunit 12A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4659

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-155-8721

--


Antigen:
Rad9

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q99638

Gene Symbols:
RAD9A

Immunogen:
Between 350 and C-term

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
RAD9A

Gene Alias:
Cell cycle checkpoint control protein, RAD 9 (S pombe) homolog, RAD9 homolog A, RAD9 homolog, RAD9A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5883

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-155-8722

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Antigen:
P4HA2

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
O15460

Gene Symbols:
P4HA2

Immunogen:
Between 250 and 300

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
P4HA2

Gene Alias:
4-PH alpha 2, 4-PH alpha-2, C-P4Halpha(II), collagen prolyl 4-hydroxylase alpha(II), procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II, procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2, prolyl 4-hydr

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8974

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-155-8724

--


Antigen:
P4HA2

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
O15460

Gene Symbols:
P4HA2

Immunogen:
Between 250 and 300

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
P4HA2

Gene Alias:
4-PH alpha 2, 4-PH alpha-2, C-P4Halpha(II), collagen prolyl 4-hydroxylase alpha(II), procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II, procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2, prolyl 4-hydr

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8974

Content And Storage:
4° C

Form:
Liquid