50-155-8716

MYPT1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

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Pack Size SKU Availability Price
Each of 1 50-155-8716-Each-of-1 In Stock ₹ 41,863.65

50-155-8716 - Each of 1

₹ 41,863.65

In Stock

Quantity

1

Base Price: ₹ 41,863.65

GST (18%): ₹ 7,535.457

Total Price: ₹ 49,399.107

Antigen

MYPT1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PPP1R12A

Gene Alias

myosin phosphatase target subunit 1; myosin phosphatase, target subunit 1; myosin phosphatase-targeting subunit 1; protein phosphatase 1 regulatory subunit 12A

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4659

Content And Storage

4° C

Form

Liquid

Applications

Immunoprecipitation, Western Blot

Concentration

0.2 mg/ml

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.

O14974

Gene Symbols

PPP1R12A

Immunogen

Between 800 and 850

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase
  • Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho
  • The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells
  • The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC
  • Rho-associated kinase (Rho-kinase), which is activated by GTP
  • RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase
  • Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosphorylation of MBS and MLC
  • Thus, Rho appears to inhibit myosin phosphatase through the action of Rho-kinase
  • Several transcript variants encoding different isoforms have been found for this gene.

Compare Similar Items

Show Difference

Img

Bethyl Laboratories, Inc

50-155-8716

--


Antigen:
MYPT1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PPP1R12A

Gene Alias:
myosin phosphatase target subunit 1; myosin phosphatase, target subunit 1; myosin phosphatase-targeting subunit 1; protein phosphatase 1 regulatory subunit 12A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4659

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
0.2 mg/ml

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
O14974

Gene Symbols:
PPP1R12A

Immunogen:
Between 800 and 850

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-8718

--


Antigen:
MYPT1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PPP1R12A

Gene Alias:
myosin phosphatase target subunit 1; myosin phosphatase, target subunit 1; myosin phosphatase-targeting subunit 1; protein phosphatase 1 regulatory subunit 12A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4659

Content And Storage:
4° C

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
O14974

Gene Symbols:
PPP1R12A

Immunogen:
Between 800 and 850

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-8721

--


Antigen:
Rad9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAD9A

Gene Alias:
Cell cycle checkpoint control protein, RAD 9 (S pombe) homolog, RAD9 homolog A, RAD9 homolog, RAD9A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5883

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
__

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q99638

Gene Symbols:
RAD9A

Immunogen:
Between 350 and C-term

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-8722

--


Antigen:
P4HA2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
P4HA2

Gene Alias:
4-PH alpha 2, 4-PH alpha-2, C-P4Halpha(II), collagen prolyl 4-hydroxylase alpha(II), procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II, procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2, prolyl 4-hydr

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8974

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
0.2 mg/ml

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
O15460

Gene Symbols:
P4HA2

Immunogen:
Between 250 and 300

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG