50-168-1603

ISG15 Mouse anti-Human, Clone: OTI6C8, liquid, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-1603-Each-of-1 In Stock ₹ 43,217.21

50-168-1603 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

ISG15

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P05161

Gene Symbols

ISG15

Immunogen

Human recombit protein fragment corresponding to amino acids 1-157 of human ISG15 produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI6C8

Conjugate

Unconjugated

Gene

ISG15

Gene Alias

G1P2, IFI15, IMD38, IP17, UCRP, hUCRP

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9636

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Ubiquitin-like protein ISG15 plays a key role in the innate immune response to viral infection either via its conjugation to a target protein (ISGylation) or via its action as a free or unconjugated protein
  • It is secreted from monocytes in response to type I interferons and causes natural killer (NK)-cell proliferation and an augmentation of non-MCH (major histocompatibility complex)-restricted cytotoxicity
  • Synthesis is stimulated by IFN-alpha or IFN-beta or IFN-omega , but not IFN-gamma
  • ISG15 expression is also induced by overexpression of interferon regulatory factors that participate in transcriptional regulation of IFN genes, and by influenza B virus
  • ISG15 is secreted by cell lines of monocyte, T-lymphocyte, B-lymphocyte, human fibroblasts, and epithelial origins
  • Enhancement of NK cell proliferation, augmentation of non-major histocompatibility complex-restricted cytotoxicity, and induction of IFN-gamma from T cells identify ISG15 as a member of the cytokine cascade and suggest that it may be responsible for amplifying and directing some of the immunomodulatory effects of IFN-alpha or IFN-beta
  • ISG15 has has also been shown to function intracellularly as a ubiquitin homolog
  • Mutations affecting the gene can result in Immunodeficiency 38, with basal ganglia calcification (IMD38).

Compare Similar Items

Show Difference

Img

OriGene

50-168-1603

--


Antigen:
ISG15

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P05161

Gene Symbols:
ISG15

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-157 of human ISG15 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI6C8

Conjugate:
Unconjugated

Gene:
ISG15

Gene Alias:
G1P2, IFI15, IMD38, IP17, UCRP, hUCRP

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9636

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1604

--


Antigen:
CSF3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P09919

Gene Symbols:
CSF3

Immunogen:
Human recombit protein fragment corresponding to amino acids 30-200 of human CSF3 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI4H9

Conjugate:
Unconjugated

Gene:
CSF3

Gene Alias:
C17orf33, CSF3OS, GCSF

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1440

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1605

--


Antigen:
DMRT1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9Y5R6

Gene Symbols:
DMRT1

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-210 of human DMRT1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4B5

Conjugate:
Unconjugated

Gene:
DMRT1

Gene Alias:
CT154, DMT1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1761

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1608

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Antigen:
FBXO8

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9NRD0

Gene Symbols:
FBXO8

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-231 of human FBXO8 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI9G5

Conjugate:
Unconjugated

Gene:
FBXO8

Gene Alias:
DC10, FBS, FBX8

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26269

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid