50-168-1666

PDGFRA Monoclonal Antibody (OTI4E7), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-1666-Each-of-1 In Stock ₹ 43,217.21

50-168-1666 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

PDGFRA

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P16234

Gene Symbols

PDGFRA

Immunogen

Human recombit protein fragment corresponding to amino acids 789-1089 of human PDGFRA produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI4E7

Conjugate

Unconjugated

Gene

PDGFRA

Gene Alias

CD140A, PDGFR-2, PDGFR2

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5156

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Related Products

Img

OriGene

50-168-1676

--

Img

OriGene

50-168-1677

--

Img

OriGene

50-168-1665

--

Img

OriGene

50-168-1668

--

Img

OriGene

50-168-1032

--

Img

OriGene

50-168-1077

--

Img

OriGene

50-168-1123

--

Img

OriGene

50-168-1523

--

Description

  • PDGFRA (PDGFR-alpha, Platelet Derived Growth Factor Receptor alpha) belongs to the protein tyrosine kinase family, and binds to the alpha chain of PDGF
  • PDGFR exhibits two different isoforms, alpha and beta, which are coded by two different genes
  • PDGF-alpha receptors are expressed in oligodendrocyte progenitor cells while PDGF-beta receptors are expressed on neurons
  • PDGFR possess five immunoglobulin like domains that are involved in ligand binding
  • Two tyrosine kinase domains are separated by a kinase insert to which PI-3 kinase can bind
  • PDGF AA can bind and activate only PDGFR alpha, while PDGF BB can bind and activate both PDGFR alpha and beta
  • Members of the PDGF receptor subfamily are cell surface receptors that act as mitogens for cells of mesenchymal origin, and consist of alpha and beta isoforms of ∽190 and 125 kDa, respectively
  • Activated PDGF receptors act on signaling pathways that control cell growth, actin reorganization, migration, and differentiation
  • In humans, the gene is located on the q arm of chromosome 4
  • Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.

Compare Similar Items

Show Difference

Img

OriGene

50-168-1666

--


Antigen:
PDGFRA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P16234

Gene Symbols:
PDGFRA

Immunogen:
Human recombit protein fragment corresponding to amino acids 789-1089 of human PDGFRA produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI4E7

Conjugate:
Unconjugated

Gene:
PDGFRA

Gene Alias:
CD140A, PDGFR-2, PDGFR2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5156

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1668

--


Antigen:
PDGFRA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P16234

Gene Symbols:
PDGFRA

Immunogen:
Human recombit protein fragment corresponding to amino acids 789-1089 of human PDGFRA produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1C10

Conjugate:
Unconjugated

Gene:
PDGFRA

Gene Alias:
CD140A, PDGFR-2, PDGFR2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5156

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1669

--


Antigen:
CSF3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P09919

Gene Symbols:
CSF3

Immunogen:
Human recombit protein fragment corresponding to amino acids 30-200 of human CSF3 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI7B3

Conjugate:
Unconjugated

Gene:
CSF3

Gene Alias:
C17orf33, CSF3OS, GCSF

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1440

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1673

--


Antigen:
LIME1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9H400

Gene Symbols:
LIME1

Immunogen:
Human recombit protein fragment corresponding to amino acids 30-295 of human LIME1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI3B10

Conjugate:
Unconjugated

Gene:
LIME1

Gene Alias:
LIME, dJ583P15.4

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54923

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid