50-168-1677

PDGFRA Monoclonal Antibody (OTI3F4), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-1677-Each-of-1 In Stock ₹ 43,217.21

50-168-1677 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

PDGFRA

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P16234

Gene Symbols

PDGFRA

Immunogen

Human recombit protein fragment corresponding to amino acids 789-1089 of human PDGFRA produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

Applications

Western Blot

Clone

OTI3F4

Conjugate

Unconjugated

Gene

PDGFRA

Gene Alias

CD140A, PDGFR-2, PDGFR2

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5156

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • PDGFRA (PDGFR-alpha, Platelet Derived Growth Factor Receptor alpha) belongs to the protein tyrosine kinase family, and binds to the alpha chain of PDGF
  • PDGFR exhibits two different isoforms, alpha and beta, which are coded by two different genes
  • PDGF-alpha receptors are expressed in oligodendrocyte progenitor cells while PDGF-beta receptors are expressed on neurons
  • PDGFR possess five immunoglobulin like domains that are involved in ligand binding
  • Two tyrosine kinase domains are separated by a kinase insert to which PI-3 kinase can bind
  • PDGF AA can bind and activate only PDGFR alpha, while PDGF BB can bind and activate both PDGFR alpha and beta
  • Members of the PDGF receptor subfamily are cell surface receptors that act as mitogens for cells of mesenchymal origin, and consist of alpha and beta isoforms of ∽190 and 125 kDa, respectively
  • Activated PDGF receptors act on signaling pathways that control cell growth, actin reorganization, migration, and differentiation
  • In humans, the gene is located on the q arm of chromosome 4
  • Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.

Compare Similar Items

Show Difference

Img

OriGene

50-168-1677

--


Antigen:
PDGFRA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P16234

Gene Symbols:
PDGFRA

Immunogen:
Human recombit protein fragment corresponding to amino acids 789-1089 of human PDGFRA produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Western Blot

Clone:
OTI3F4

Conjugate:
Unconjugated

Gene:
PDGFRA

Gene Alias:
CD140A, PDGFR-2, PDGFR2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5156

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1679

--


Antigen:
AMT

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P48728

Gene Symbols:
AMT

Immunogen:
Human recombit protein fragment corresponding to amino acids 146-403 of human AMT produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI4C9

Conjugate:
Unconjugated

Gene:
AMT

Gene Alias:
GCE, GCST, GCVT, NKH

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
275

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1680

--


Antigen:
RPL10

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P27635

Gene Symbols:
RPL10

Immunogen:
Full length human recombit protein of human RPL10 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI6B11

Conjugate:
Unconjugated

Gene:
RPL10

Gene Alias:
AUTSX5, DXS648, DXS648E, L10, MRXS35, NOV, QM

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6134

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1681

--


Antigen:
KCTD9

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q7L273

Gene Symbols:
KCTD9

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-223 of human KCTD9 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI5F11

Conjugate:
Unconjugated

Gene:
KCTD9

Gene Alias:
BTBD27

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54793

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid