50-168-1793

IGF1R Mouse anti-Human, Clone: OTI4C4, liquid, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-1793-Each-of-1 In Stock ₹ 43,217.21

50-168-1793 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

IGF1R

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P08069

Gene Symbols

IGF1R

Immunogen

Human recombit protein fragment corresponding to amino acids 741-935 of human IGF1R produced in Insect.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI4C4

Conjugate

Unconjugated

Gene

IGF1R

Gene Alias

CD221, IGFIR, IGFR, JTK13

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3480

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Insulin growth factor 1 receptor belongs to the family of tyrosine receptor kinases
  • It is involved in activation of various substrates including IGF and neurotensin, regulation of metabolism, cell division, maintece, and inflammation response
  • The protein is a tetramer consisting of two alpha, and two beta subunits
  • The alpha-subunits binds to insulin growth factor 1 with higher affinity than to insulin growth factor 2
  • Binding results in a conformational change, followed by autophosphorylation of IGF-1R at positions 1134, 1135, 1136
  • The activated IGF-1R in turn, causes phosphorylation of substrate proteins, followed by sequential activation of RAS, RAF, and mitogen-activated protein kinase isoforms ERK, p38, and JNK, leading to the transcription of genes that drive proliferation.

Compare Similar Items

Show Difference

Img

OriGene

50-168-1793

--


Antigen:
IGF1R

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P08069

Gene Symbols:
IGF1R

Immunogen:
Human recombit protein fragment corresponding to amino acids 741-935 of human IGF1R produced in Insect.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI4C4

Conjugate:
Unconjugated

Gene:
IGF1R

Gene Alias:
CD221, IGFIR, IGFR, JTK13

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3480

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1795

--


Antigen:
TNFA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P01375

Gene Symbols:
TNF

Immunogen:
Full length human recombit protein of human TNF produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
OTI4B9

Conjugate:
Unconjugated

Gene:
TNF

Gene Alias:
DIF, TNF-alpha, TNFA, TNFSF2, TNLG1F

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7124

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1797

--


Antigen:
EGFL7

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9UHF1

Gene Symbols:
EGFL7

Immunogen:
Human recombit protein fragment corresponding to amino acids 24-273 of human EGFL7 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI5F12

Conjugate:
Unconjugated

Gene:
EGFL7

Gene Alias:
NEU1, VE-STATIN, ZNEU1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51162

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1798

--


Antigen:
TNNT2

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P45379

Gene Symbols:
TNNT2

Immunogen:
Full length human recombit protein of human TNNT2 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI7D2

Conjugate:
Unconjugated

Gene:
TNNT2

Gene Alias:
CMD1D, CMH2, CMPD2, LVNC6, RCM3, TnTC, cTnT

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7139

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid