50-168-3880

AIFM1 Monoclonal Antibody (OTI8B8), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-3880-Each-of-1 In Stock ₹ 43,217.21

50-168-3880 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

AIFM1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

O95831

Gene Symbols

AIFM1

Immunogen

Human recombit protein fragment corresponding to amino acids 134-483 of human AIFM1 produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI8B8

Conjugate

Unconjugated

Gene

AIFM1

Gene Alias

AIF, CMT2D, CMTX4, COWCK, COXPD6, DFNX5, NADMR, NAMSD, PDCD8

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9131

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Apoptosis Inducing Factor (AIF) causes chromatin condensation and DNA fragmentation
  • AIF was recently identified, and cloned
  • Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation
  • These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins
  • Like the critical molecules, cytochrome c and caspase-9, in apoptosis, AIF localizes in mitochondria
  • AIF translocates to the nucleus when apoptosis is induced and induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9
  • AIF induces chromatin condensation and large scale DNA fragmentation, which are the hallmarks of apoptosis, of the isolated nucleus and the nucleus in live cells by microinjection and apoptosis stimuli
  • AIF is highly conserved between human and mouse and widely expressed
  • Mutations in the AIF gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy
  • Alternative splicing results in multiple transcript variants of AIF and a related pseudogene has been identified on chromosome 10.

Compare Similar Items

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Img

OriGene

50-168-3880

--


Antigen:
AIFM1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O95831

Gene Symbols:
AIFM1

Immunogen:
Human recombit protein fragment corresponding to amino acids 134-483 of human AIFM1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI8B8

Conjugate:
Unconjugated

Gene:
AIFM1

Gene Alias:
AIF, CMT2D, CMTX4, COWCK, COXPD6, DFNX5, NADMR, NAMSD, PDCD8

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9131

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-3881

--


Antigen:
MSL2

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9HCI7

Gene Symbols:
MSL2

Immunogen:
Full length human recombit protein of human MSL2 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
OTI4G7

Conjugate:
Unconjugated

Gene:
MSL2

Gene Alias:
MSL-2, MSL2L1, RNF184

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55167

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-3882

--


Antigen:
MSL2

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9HCI7

Gene Symbols:
MSL2

Immunogen:
Full length human recombit protein of human MSL2 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
OTI6C10

Conjugate:
Unconjugated

Gene:
MSL2

Gene Alias:
MSL-2, MSL2L1, RNF184

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55167

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-3886

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Antigen:
PPM1D

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O15297

Gene Symbols:
PPM1D

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-375 of human PPM1D produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI3E1

Conjugate:
Unconjugated

Gene:
PPM1D

Gene Alias:
IDDGIP, PP2C-DELTA, WIP1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8493

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid