50-168-4904
ERBB2 Mouse anti-Canine, Human, Clone: UMAB35, lyophilized, UltraMAB™
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-168-4904-Each-of-1 | In Stock | ₹ 65,489.76 |
50-168-4904 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 65,489.76
GST (18%): ₹ 11,788.157
Total Price: ₹ 77,277.917
Antigen
ERBB2
Classification
Monoclonal
Conjugate
Unconjugated
Gene
ERBB2
Gene Alias
CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2064, 403883
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Lyophilized
Applications
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Peptide Array, Western Blot
Clone
UMAB35
Formulation
PBS with 8% trehalose and no preservative
Gene Accession No.
O18735, P04626
Gene Symbols
ERBB2
Immunogen
Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Canine, Human
Product Type
Antibody
Isotype
IgG2b
Description
- ErbB2 (Her2/neu) is a 185 kDa transmembrane receptor tyrosine kinase from the EGFR (epidermal growth factor receptor) family that regulates biological responses such as cell growth, differentiation, and tissue development
- ErbB2 has no ligand binding domain of its own and cannot bind growth factors
- However, ErbB2 does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signaling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase
- Autophosphorylation of tyrosine 1139 on ErbB2 allows binding of Grb2 and the Src SH2 domain, which allows activation of the Ras, Raf, ERK1/2 and JAK/STAT signaling pathways, respectively
- Alternative splicing of ErbB2 results in several transcript variants, some encoding different isoforms and others that have not been fully characterized
- In humans, the gene encoding ERBB2 is present on chromosome 17
- Amplification and/or overexpression of the ErbB2 gene has been reported in ovarian tumors, breast, lung and skin cancer.
Compare Similar Items
Show Difference
Antigen: ERBB2
Classification: Monoclonal
Conjugate: Unconjugated
Gene: ERBB2
Gene Alias: CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2064, 403883
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Peptide Array, Western Blot
Clone: UMAB35
Formulation: PBS with 8% trehalose and no preservative
Gene Accession No.: O18735, P04626
Gene Symbols: ERBB2
Immunogen: Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Canine, Human
Product Type: Antibody
Isotype: IgG2b
Antigen:
ERBB2
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
ERBB2
Gene Alias:
CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2064, 403883
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Peptide Array, Western Blot
Clone:
UMAB35
Formulation:
PBS with 8% trehalose and no preservative
Gene Accession No.:
O18735, P04626
Gene Symbols:
ERBB2
Immunogen:
Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Canine, Human
Product Type:
Antibody
Isotype:
IgG2b
Antigen: ERBB2
Classification: Monoclonal
Conjugate: Unconjugated
Gene: ERBB2
Gene Alias: CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13866, 2064, 24337
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: UMAB36
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P04626, P06494, P70424
Gene Symbols: ERBB2
Immunogen: Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Antigen:
ERBB2
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
ERBB2
Gene Alias:
CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13866, 2064, 24337
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
UMAB36
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P04626, P06494, P70424
Gene Symbols:
ERBB2
Immunogen:
Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Antigen: ERBB2
Classification: Monoclonal
Conjugate: Unconjugated
Gene: ERBB2
Gene Alias: CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13866, 2064, 24337
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Peptide Array, Western Blot
Clone: UMAB36
Formulation: PBS with 8% trehalose and no preservative
Gene Accession No.: P04626, P06494, P70424
Gene Symbols: ERBB2
Immunogen: Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Antigen:
ERBB2
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
ERBB2
Gene Alias:
CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13866, 2064, 24337
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Peptide Array, Western Blot
Clone:
UMAB36
Formulation:
PBS with 8% trehalose and no preservative
Gene Accession No.:
P04626, P06494, P70424
Gene Symbols:
ERBB2
Immunogen:
Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Antigen: XRCC1
Classification: Monoclonal
Conjugate: Unconjugated
Gene: XRCC1
Gene Alias: RCC, SCAR26
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7515
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Peptide Array
Clone: UMAB40
Formulation: PBS with 8% trehalose and no preservative
Gene Accession No.: P18887
Gene Symbols: XRCC1
Immunogen: Full length human recombit protein of human XRCC1 produced in HEK293T cell.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
XRCC1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
XRCC1
Gene Alias:
RCC, SCAR26
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7515
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Peptide Array
Clone:
UMAB40
Formulation:
PBS with 8% trehalose and no preservative
Gene Accession No.:
P18887
Gene Symbols:
XRCC1
Immunogen:
Full length human recombit protein of human XRCC1 produced in HEK293T cell.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1