50-177-03
Cytochrome C Monoclonal Antibody (2B5), eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-177-03-Each-of-1 | In Stock | ₹ 29,946.00 |
50-177-03 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 29,946.00
GST (18%): ₹ 5,390.28
Total Price: ₹ 35,336.28
Antigen
Cytochrome C
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative; pH 7.2-7.4
Gene Accession No.
P99999
Gene Symbols
Cycs
Immunogen
Rec. Human Cytochrome C
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
2B5
Conjugate
Unconjugated
Gene
Cycs
Gene Alias
CG17903; CG17903-PA; CG17903-PB; CRF; CYC; CYC2; Cycs; CYCSA; Cyct-c-p; Cyt c; cyt c-p; cyt.c; CytC; Cyt-c; CYTC2; Cyt-c2; CytC-2; cyt-c-p; cytC-p; Cyt-c-p-PA; Cyt-c-p-PB; Cytochrome c; cytochrome c DC4; Cytochrome c proximal; Cytochrome C, expressed in somatic tissues; cytochrome c, somatic; Cytochrome c-2; cytochrome c-like; cytochrome c-like protein; Cytochrome c-proximal; cytochrome-c-p; Cytochrome-c-proximal; DC4; dCyt.C-p; DMc01; Dmel\CG17903; Dmel_CG17903; hc1; HCS; l(2)k13905; lethal (2) k13905; LOC100341175; LOC100357840; MGC128356 protein; pDMc01; RH17228p; THC4
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
54205
Content And Storage
4° C
Form
Liquid
Related Products
Description
- Description: Cytochrome c was identified as a component required for the crucial steps in apoptosis, caspase-3 activation and DNA fragmentation
- Cytochrome c was shown to redistribute from mitochondria to cytosol during apoptosis in intact cells
- Mitochrondrial cytochrome c is a water-soluble protein of 15 kDa with a net positive charge, residing loosely attached in the mitochrondrial intermembrane space
- Cytochrome c functions in the respiratory chain by interaction with redox partners
- The release of cytochrome c into the cytosol leads to an activation of an apoptotic program via activation of a caspase dependent pathway
- Cytochrome c achieves this goal by interaction with other cytosolic factors forming a complex (apoptosome) composed of cytochrome c, Apaf-1, dATP and Apaf-3/caspase 9
- Bcl-2 on the other hand was shown to be able to prevent apoptosis by blocking the release of cytochrome c from mitochondria
- Applications Tested: ELISA, Flow Cytometry, Western Blotting
- Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in oxidative phosphorylation and the production of cellular ATP
- Release of cytochrome C from the mitochondria to the cytosol is triggered by apoptotic stimuli
- In the cytoplasm, the cytochrome C binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9
- Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.
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Antigen: Cytochrome C
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative; pH 7.2-7.4
Gene Accession No.: P99999
Gene Symbols: Cycs
Immunogen: Rec. Human Cytochrome C
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: 2B5
Conjugate: Unconjugated
Gene: Cycs
Gene Alias: CG17903; CG17903-PA; CG17903-PB; CRF; CYC; CYC2; Cycs; CYCSA; Cyct-c-p; Cyt c; cyt c-p; cyt.c; CytC; Cyt-c; CYTC2; Cyt-c2; CytC-2; cyt-c-p; cytC-p; Cyt-c-p-PA; Cyt-c-p-PB; Cytochrome c; cytochrome c DC4; Cytochrome c proximal; Cytochrome C, expressed in somatic tissues; cytochrome c, somatic; Cytochrome c-2; cytochrome c-like; cytochrome c-like protein; Cytochrome c-proximal; cytochrome-c-p; Cytochrome-c-proximal; DC4; dCyt.C-p; DMc01; Dmel\CG17903; Dmel_CG17903; hc1; HCS; l(2)k13905; lethal (2) k13905; LOC100341175; LOC100357840; MGC128356 protein; pDMc01; RH17228p; THC4
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 54205
Content And Storage: 4° C
Form: Liquid
Antigen:
Cytochrome C
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative; pH 7.2-7.4
Gene Accession No.:
P99999
Gene Symbols:
Cycs
Immunogen:
Rec. Human Cytochrome C
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
2B5
Conjugate:
Unconjugated
Gene:
Cycs
Gene Alias:
CG17903; CG17903-PA; CG17903-PB; CRF; CYC; CYC2; Cycs; CYCSA; Cyct-c-p; Cyt c; cyt c-p; cyt.c; CytC; Cyt-c; CYTC2; Cyt-c2; CytC-2; cyt-c-p; cytC-p; Cyt-c-p-PA; Cyt-c-p-PB; Cytochrome c; cytochrome c DC4; Cytochrome c proximal; Cytochrome C, expressed in somatic tissues; cytochrome c, somatic; Cytochrome c-2; cytochrome c-like; cytochrome c-like protein; Cytochrome c-proximal; cytochrome-c-p; Cytochrome-c-proximal; DC4; dCyt.C-p; DMc01; Dmel\CG17903; Dmel_CG17903; hc1; HCS; l(2)k13905; lethal (2) k13905; LOC100341175; LOC100357840; MGC128356 protein; pDMc01; RH17228p; THC4
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
54205
Content And Storage:
4° C
Form:
Liquid
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