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50-177-63

ErbB2 (HER-2) Monoclonal Antibody (2G11), Biotin, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

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Pack Size SKU Availability Price
Each of 1 50-177-63-Each-of-1 In Stock ₹ 24,983.52

50-177-63 - Each of 1

₹ 24,983.52

In Stock

Quantity

1

Base Price: ₹ 24,983.52

GST (18%): ₹ 4,497.034

Total Price: ₹ 29,480.554

Antigen

ErbB2 (HER-2)

Classification

Monoclonal

Concentration

10 μL/Test

Formulation

TBS with 1% BSA and 0.02% sodium azide; pH 7.2-7.4

Gene Accession No.

P04626

Gene Symbols

ERBB2

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2064

Content And Storage

2-8°C

Form

Liquid

Applications

Flow Cytometry

Clone

2G11

Conjugate

Biotin

Gene

ERBB2

Gene Alias

avian erythroblastosis oncogene B 2; Avian erythroblastosis viral (v-erb-B2) oncogene homologue 2 (neuro/glioblastoma derived oncogene homolog); CD antigen CD340; CD340; c-erb B2/neu protein; c-erbB2; C-erbB-2; c-neu; epidermal growth factor receptor-related protein; erbb 2; ERBB2; erb-b2; Erbb-2; ErbB2 (pTyr1139); ErbB2 (pY1139); ErbB2 phospho Y1139; erb-b2 receptor tyrosine kinase 2; her 2; HER2; HER-2; HER-2/neu; herstatin; human epidermal growth factor receptor 2; Kiaa3023; metas; Metastatic lymph node gene 19 protein; mKIAA3023; MLN 19; MLN19; NEU; Neu oncogene; NEU proto-oncogene; neuro/glioblastoma derived oncogene homolog; neuroblastoma/glioblastoma derived oncogene homolog; NGL; p185erbB2; p185neu; phospho ErbB2; proto-oncogene c-ErbB-2; Proto-oncogene Neu; receptor tyrosine-protein kinase erbB-2; TKR1; Tyrosine kinase-type cell surface receptor HER2; v-erb-b2 avian erythroblastic leukemia viral oncogene 2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • Description: The antibody (2G11) can be used to stain cryostat sections or cell smears
  • BMS120 is also suitable as primary antibody in staining for FACS analysis, BMS120FI can be used for direct staining of cells, BMS120BT can be used in a 2-step procedure using the biotin-(strept)avidin system
  • The epitope is located in the extracellular domain, no cross reactivity with EGF-R has been detected by immunoprecipitation
  • Both HER-2 oncogene amplification and oncoprotein overexpression have been correlated with breast, ovarian, gastric, lung, and other cancers
  • In 15-40 % of primary breast cancers, amplification of the HER-2 oncogen is found which is highly correlated with overexpression of the encoded protein and seems to play a major role especially during the initiation of ductal carcinomas
  • HER-2 overexpression is described as independent prognostic factor with greater predictive power than most of the currently used prognostic tools - especially in axillary lymph-node-positive breast cancer patients
  • 32 % of ovarian carcinomas overexpress the HER-2 oncoprotein
  • Survival of those patients is significantly worse compared with cases of normal HER-2 protein expression
  • Additionally, patients whose tumors have high HER-2 protein expression are significantly less likely to have a complete response to primary therapy
  • A correlation between HER-2 expression, and clinical outcome has been also demonstrated for head and neck, salivary gland and placental carcinomas
  • ErbB2 (HER2) is a receptor tyrosine kinase that is overexpressed in some breast tumors
  • Herceptin, used in treatment of metastatic Her2-positive cancer, is monoclonal antibody targeting this kinase.

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Invitrogen

50-177-63

--

Antigen:
ErbB2 (HER-2)
Classification:
Monoclonal
Concentration:
10 μL/Test
Formulation:
TBS with 1% BSA and 0.02% sodium azide; pH 7.2-7.4
Gene Accession No.:
P04626
Gene Symbols:
ERBB2
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2064
Content And Storage:
2-8°C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
2G11
Conjugate:
Biotin
Gene:
ERBB2
Gene Alias:
avian erythroblastosis oncogene B 2; Avian erythroblastosis viral (v-erb-B2) oncogene homologue 2 (neuro/glioblastoma derived oncogene homolog); CD antigen CD340; CD340; c-erb B2/neu protein; c-erbB2; C-erbB-2; c-neu; epidermal growth factor receptor-related protein; erbb 2; ERBB2; erb-b2; Erbb-2; ErbB2 (pTyr1139); ErbB2 (pY1139); ErbB2 phospho Y1139; erb-b2 receptor tyrosine kinase 2; her 2; HER2; HER-2; HER-2/neu; herstatin; human epidermal growth factor receptor 2; Kiaa3023; metas; Metastatic lymph node gene 19 protein; mKIAA3023; MLN 19; MLN19; NEU; Neu oncogene; NEU proto-oncogene; neuro/glioblastoma derived oncogene homolog; neuroblastoma/glioblastoma derived oncogene homolog; NGL; p185erbB2; p185neu; phospho ErbB2; proto-oncogene c-ErbB-2; Proto-oncogene Neu; receptor tyrosine-protein kinase erbB-2; TKR1; Tyrosine kinase-type cell surface receptor HER2; v-erb-b2 avian erythroblastic leukemia viral oncogene 2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1

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Invitrogen

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Antigen:
CD62L (L-Selectin)
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with no preservative; pH 7.2-7.4
Gene Accession No.:
P14151
Gene Symbols:
SELL
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
6402
Content And Storage:
4° C
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Frozen)
Clone:
DREG.55
Conjugate:
Unconjugated
Gene:
SELL
Gene Alias:
A.11; AI528707; CD62 antigen-like family member L; CD62L; gp90-MEL; hLHRc; LAM1; LAM-1; LECAM1; LECAM-1; LEU8; Leu-8; Leukocyte adhesion molecule 1; leukocyte surface antigen Leu-8; Leukocyte-endothelial cell adhesion molecule 1; LNHR; LSEL; L-selectin; Ly22; Ly-22; LYAM1; Lyam-1; Ly-m22; Lymph node homing receptor; lymphocyte adhesion molecule 1; lymphocyte antigen 22; Lymphocyte surface MEL-14 antigen; pln homing receptor; PLNHR; SELE; selectin E (endothelial adhesion molecule 1); selectin L; selectin L (lymphocyte adhesion molecule 1); selectin, lymphocyte; Sell; TQ1
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1

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Sigma Aldrich Fine Chemicals Biosciences

50-177-6647

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__
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__
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__
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__

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Sigma Aldrich Fine Chemicals Biosciences

50-177-6649

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Antigen:
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Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Gene Symbols:
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Purification Method:
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Gene Alias:
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Host Species:
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Quantity:
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Primary or Secondary:
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Isotype:
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