50-198-6444

Phospho-CHK2 (Ser516) Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-6444-Each-of-1 In Stock ₹ 36,897.75

50-198-6444 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Phospho-CHK2 (Ser516)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Chek2

Gene Alias

CDS1; Cds1 homolog; Checkpoint kinase 2; checkpoint-like protein CHK2; Chek2; CHK2; Chk2 (phospho T68); Chk2 (pThr68); CHK2 checkpoint homolog; Chk2 phospho; Chk2 phospho T68; del9; EC 2.7.11.1; hCds1; Hucds1; kinase Chk2; LFS2; OTTHUMP00000199044; OTTHUMP00000199045; OTTHUMP00000199064; OTTHUMP00000199115; OTTHUMP00000199116; phospho Chk2 (T68); phospho Thr68 Chk2; PP1425; protein kinase Chk2; RAD53; Rad53 homolog; RP11-436C9.1; Serine/threonine-protein kinase Chk2

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

11200

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

O96017

Gene Symbols

Chek2

Immunogen

KLH conjugated synthetic phosphopeptide derived from human CHK2 around the phosphorylation site of ser516.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Checkpoint kinase 2 (Chk2) is a serine/threonine-protein kinase which functions as a cell cycle checkpoint regulator
  • ATM and ATR kinases are activated in response to ionizing and ultraviolet radition, and phosphorylate Thr68 and other sites in the amino-terminal region of Chk2 dimerisation and activation
  • Activated Chk2 phosphorylates and inhibits Cdc25C phosphates, preventing the entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1
  • In addition, Chk2 can phosphorylate BRCA1, allowing BRCA1 to restore survival after DNA damage
  • Chk2 is a putative tumor suppressor protein, with mutations in to the Chk2 gene linked to Li-Fraumeni syndrome, a familiar cancer usually associated with inherited mutations in TP53
  • Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors.

Compare Similar Items

Show Difference

Img

Bioss

50-198-6444

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Antigen:
Phospho-CHK2 (Ser516)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Chek2

Gene Alias:
CDS1; Cds1 homolog; Checkpoint kinase 2; checkpoint-like protein CHK2; Chek2; CHK2; Chk2 (phospho T68); Chk2 (pThr68); CHK2 checkpoint homolog; Chk2 phospho; Chk2 phospho T68; del9; EC 2.7.11.1; hCds1; Hucds1; kinase Chk2; LFS2; OTTHUMP00000199044; OTTHUMP00000199045; OTTHUMP00000199064; OTTHUMP00000199115; OTTHUMP00000199116; phospho Chk2 (T68); phospho Thr68 Chk2; PP1425; protein kinase Chk2; RAD53; Rad53 homolog; RP11-436C9.1; Serine/threonine-protein kinase Chk2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11200

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O96017

Gene Symbols:
Chek2

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human CHK2 around the phosphorylation site of ser516.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-6445

--


Antigen:
Phospho-Cofilin (Tyr140)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CFL1

Gene Alias:
18 kDa phosphoprotein; AA959946; BOS_24828; CFL; Cfl1; CFL-1; Cof; COF1; cofilin; cofilin 1; cofilin 1 (non-muscle); cofilin 1, non-muscle; COFILIN protein; Cofilin, non-muscle isoform; Cofilin1; Cofilin-1; cofilin-1-like protein; epididymis secretory protein Li 15; HEL-S-15; n-cofilin; p18

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1072

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P23528

Gene Symbols:
CFL1

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human Cofilin around the phosphorylation site of Tyr140.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-6446

--


Antigen:
Phospho-CFL1 (Tyr89)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CFL1

Gene Alias:
18 kDa phosphoprotein; AA959946; BOS_24828; CFL; Cfl1; CFL-1; Cof; COF1; cofilin; cofilin 1; cofilin 1 (non-muscle); cofilin 1, non-muscle; COFILIN protein; Cofilin, non-muscle isoform; Cofilin1; Cofilin-1; cofilin-1-like protein; epididymis secretory protein Li 15; HEL-S-15; n-cofilin; p18

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1072

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P23528

Gene Symbols:
CFL1

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human CFL1/CFL2 around the phosphorylation site of Tyr89.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-6447

--


Antigen:
Phospho-CHK2 (Ser33)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Chek2

Gene Alias:
CDS1; Cds1 homolog; Checkpoint kinase 2; checkpoint-like protein CHK2; Chek2; CHK2; Chk2 (phospho T68); Chk2 (pThr68); CHK2 checkpoint homolog; Chk2 phospho; Chk2 phospho T68; del9; EC 2.7.11.1; hCds1; Hucds1; kinase Chk2; LFS2; OTTHUMP00000199044; OTTHUMP00000199045; OTTHUMP00000199064; OTTHUMP00000199115; OTTHUMP00000199116; phospho Chk2 (T68); phospho Thr68 Chk2; PP1425; protein kinase Chk2; RAD53; Rad53 homolog; RP11-436C9.1; Serine/threonine-protein kinase Chk2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11200

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O96017

Gene Symbols:
Chek2

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human CHK2 around the phosphorylation site of ser33.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG