50-198-6447

Phospho-CHK2 (Ser33) Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-6447-Each-of-1 In Stock ₹ 36,897.75

50-198-6447 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Phospho-CHK2 (Ser33)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Chek2

Gene Alias

CDS1; Cds1 homolog; Checkpoint kinase 2; checkpoint-like protein CHK2; Chek2; CHK2; Chk2 (phospho T68); Chk2 (pThr68); CHK2 checkpoint homolog; Chk2 phospho; Chk2 phospho T68; del9; EC 2.7.11.1; hCds1; Hucds1; kinase Chk2; LFS2; OTTHUMP00000199044; OTTHUMP00000199045; OTTHUMP00000199064; OTTHUMP00000199115; OTTHUMP00000199116; phospho Chk2 (T68); phospho Thr68 Chk2; PP1425; protein kinase Chk2; RAD53; Rad53 homolog; RP11-436C9.1; Serine/threonine-protein kinase Chk2

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

11200

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

O96017

Gene Symbols

Chek2

Immunogen

KLH conjugated synthetic phosphopeptide derived from human CHK2 around the phosphorylation site of ser33.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Checkpoint kinase 2 (Chk2) is a serine/threonine-protein kinase which functions as a cell cycle checkpoint regulator
  • ATM and ATR kinases are activated in response to ionizing and ultraviolet radition, and phosphorylate Thr68 and other sites in the amino-terminal region of Chk2 dimerisation and activation
  • Activated Chk2 phosphorylates and inhibits Cdc25C phosphates, preventing the entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1
  • In addition, Chk2 can phosphorylate BRCA1, allowing BRCA1 to restore survival after DNA damage
  • Chk2 is a putative tumor suppressor protein, with mutations in to the Chk2 gene linked to Li-Fraumeni syndrome, a familiar cancer usually associated with inherited mutations in TP53
  • Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors.

Compare Similar Items

Show Difference

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Bioss

50-198-6447

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Antigen:
Phospho-CHK2 (Ser33)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Chek2

Gene Alias:
CDS1; Cds1 homolog; Checkpoint kinase 2; checkpoint-like protein CHK2; Chek2; CHK2; Chk2 (phospho T68); Chk2 (pThr68); CHK2 checkpoint homolog; Chk2 phospho; Chk2 phospho T68; del9; EC 2.7.11.1; hCds1; Hucds1; kinase Chk2; LFS2; OTTHUMP00000199044; OTTHUMP00000199045; OTTHUMP00000199064; OTTHUMP00000199115; OTTHUMP00000199116; phospho Chk2 (T68); phospho Thr68 Chk2; PP1425; protein kinase Chk2; RAD53; Rad53 homolog; RP11-436C9.1; Serine/threonine-protein kinase Chk2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11200

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O96017

Gene Symbols:
Chek2

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human CHK2 around the phosphorylation site of ser33.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-6449

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Antigen:
Phospho-CDC27 (Ser427)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDC27

Gene Alias:
AI452358; AN CDC27Hs; ANAPC3; anaphase promoting complex subunit 3; Anaphase-promoting complex subunit 3; anaphase-promoting complex, protein 3; APC3; BC023187; BOS_19285; CDC27; CDC27 homolog; cdc27.S; CDC27Hs; cell division cycle 27; cell division cycle 27 homolog; cell division cycle 27 homolog (S. cerevisiae); cell division cycle 27 S homeolog; Cell division cycle protein 27 homolog; D0S1430E; D17S978E; HNUC; H-NUC; NUC2; nuc2 homolog; XELAEV_18046079mg

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
996

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P30260

Gene Symbols:
CDC27

Immunogen:
KLH conjugated synthetic phosphopeptide derived from mouse CDC27 around the phosphorylation site of Ser427.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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50-198-6453

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Antigen:
MRG15

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MORF4L1

Gene Alias:
Eaf3; Esa1p-associated factor 3 homolog; FWP006; HSPC008; HSPC061; HsT17725; MEAF3; MGC10631; mKIAA4002; MORF4L1; MORF-related gene 15 protein; MORF-related gene on chromosome 15; MORFRG15; mortality factor 4 like 1; Mortality factor 4-like protein 1; Mrg15; PP368; Protein MSL3-1; S863-6; TEG-189; testis expressed gene 189; Testis-expressed gene 189 protein; Tex189; Transcription factor-like protein MRG15

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10933

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9UBU8

Gene Symbols:
MORF4L1

Immunogen:
KLH conjugated synthetic peptide derived from human MRG15.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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50-198-6455

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Antigen:
Phospho-CHK2 (Thr387)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Chek2

Gene Alias:
CDS1; Cds1 homolog; Checkpoint kinase 2; checkpoint-like protein CHK2; Chek2; CHK2; Chk2 (phospho T68); Chk2 (pThr68); CHK2 checkpoint homolog; Chk2 phospho; Chk2 phospho T68; del9; EC 2.7.11.1; hCds1; Hucds1; kinase Chk2; LFS2; OTTHUMP00000199044; OTTHUMP00000199045; OTTHUMP00000199064; OTTHUMP00000199115; OTTHUMP00000199116; phospho Chk2 (T68); phospho Thr68 Chk2; PP1425; protein kinase Chk2; RAD53; Rad53 homolog; RP11-436C9.1; Serine/threonine-protein kinase Chk2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11200

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O96017

Gene Symbols:
Chek2

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human CHK2 around the phosphorylation site of Thr387.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG