50-198-6455

Phospho-CHK2 (Thr387) Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-6455-Each-of-1 In Stock ₹ 36,897.75

50-198-6455 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Phospho-CHK2 (Thr387)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Chek2

Gene Alias

CDS1; Cds1 homolog; Checkpoint kinase 2; checkpoint-like protein CHK2; Chek2; CHK2; Chk2 (phospho T68); Chk2 (pThr68); CHK2 checkpoint homolog; Chk2 phospho; Chk2 phospho T68; del9; EC 2.7.11.1; hCds1; Hucds1; kinase Chk2; LFS2; OTTHUMP00000199044; OTTHUMP00000199045; OTTHUMP00000199064; OTTHUMP00000199115; OTTHUMP00000199116; phospho Chk2 (T68); phospho Thr68 Chk2; PP1425; protein kinase Chk2; RAD53; Rad53 homolog; RP11-436C9.1; Serine/threonine-protein kinase Chk2

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

11200

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

O96017

Gene Symbols

Chek2

Immunogen

KLH conjugated synthetic phosphopeptide derived from human CHK2 around the phosphorylation site of Thr387.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Checkpoint kinase 2 (Chk2) is a serine/threonine-protein kinase which functions as a cell cycle checkpoint regulator
  • ATM and ATR kinases are activated in response to ionizing and ultraviolet radition, and phosphorylate Thr68 and other sites in the amino-terminal region of Chk2 dimerisation and activation
  • Activated Chk2 phosphorylates and inhibits Cdc25C phosphates, preventing the entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1
  • In addition, Chk2 can phosphorylate BRCA1, allowing BRCA1 to restore survival after DNA damage
  • Chk2 is a putative tumor suppressor protein, with mutations in to the Chk2 gene linked to Li-Fraumeni syndrome, a familiar cancer usually associated with inherited mutations in TP53
  • Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors.

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Bioss

50-198-6455

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Antigen:
Phospho-CHK2 (Thr387)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Chek2

Gene Alias:
CDS1; Cds1 homolog; Checkpoint kinase 2; checkpoint-like protein CHK2; Chek2; CHK2; Chk2 (phospho T68); Chk2 (pThr68); CHK2 checkpoint homolog; Chk2 phospho; Chk2 phospho T68; del9; EC 2.7.11.1; hCds1; Hucds1; kinase Chk2; LFS2; OTTHUMP00000199044; OTTHUMP00000199045; OTTHUMP00000199064; OTTHUMP00000199115; OTTHUMP00000199116; phospho Chk2 (T68); phospho Thr68 Chk2; PP1425; protein kinase Chk2; RAD53; Rad53 homolog; RP11-436C9.1; Serine/threonine-protein kinase Chk2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11200

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O96017

Gene Symbols:
Chek2

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human CHK2 around the phosphorylation site of Thr387.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-6456

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Antigen:
Phospho-CaMK2 (Thr305)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Camk2b

Gene Alias:
[d]-CaMKII; 2810011D23Rik; 8030469K03Rik; alpha CaM kinase II; alpha-CaMKII; Ca++/calmodulin-dependent protein kinase 2 delta subunit; Ca++/calmodulin-dependent protein kinase II beta subunit; Ca++/calmodulin-dependent protein kinase II delta subunit; Ca++/calmodulin-dependent protein kinase II, delta subunit; Ca2+/calmodulin-dependent protein kinase II; Ca2+/calmodulin-dependent protein kinase II alpha; calcium/calmodulin dependent protein kinase II alpha; calcium/calmodulin dependent protein kinase II beta; calcium/calmodulin dependent protein kinase II delta; calcium/calmodulin dependent protein kinase II gamma; calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha; calcium/calmodulin-dependent protein kinase (CaM kinase) II beta; calcium/calmodulin-dependent protein kinase (CaM kinase) II delta; calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma; calcium/calmodulin-dependent protein kinase II alpha; calcium/calmodulin-dependent protein kinase II alpha subunit; calcium/calmodulin-dependent protein kinase II alpha-B subunit; calcium/calmodulin-dependent protein kinase II beta; calcium/calmodulin-dependent protein kinase II delta; calcium/calmodulin-dependent protein kinase II gamma; calcium/calmodulin-dependent protein kinase II, beta; calcium/calmodulin-dependent protein kinase II, delta; calcium/calmodulin-dependent protein kinase type II alpha chain; calcium/calmodulin-dependent protein kinase type II beta chain; calcium/calmodulin-dependent protein kinase type II delta chain; calcium/calmodulin-dependent protein kinase type II gamma chain; Calcium/calmodulin-dependent protein kinase type II subunit alpha; Calcium/calmodulin-dependent protein kinase type II subunit beta; Calcium/calmodulin-dependent protein kinase type II subunit delta; Calcium/calmodulin-dependent protein kinase type II subunit gamma; CaM kinase II alpha subunit; CaM kinase II beta subunit; CaM kinase II delta subunit; CaM kinase II subunit alpha; CaM kinase II subunit beta; CaM kinase II subunit delta; CaM kinase II subunit gamma; CAM2; CAMK; CaMK II; CAMK1; CAMK2; CAMK2A; Camk2b; Camk2d; Camk2g; CAMKA; CAMKB; CAMKD; CAMKG; Camki; CaMKII; CAMK-II; CaMK-II alpha subunit; CaMK-II delta subunit; caMK-II subunit alpha; caMK-II subunit beta; caMK-II subunit delta; caMK-II subunit gamma; CaMKIINalpha; caM-kinase II alpha chain; caM-kinase II beta chain; caM-kinase II delta chain; caM-kinase II gamma chain; Ck2b; KIAA0968; Kiaa4163; mKIAA0968; PK2CDD; PKCCD; proline rich calmodulin-dependent protein kinase; R74975; RATCAMKI

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
815, 816, 817, 818

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q13554, Q13555, Q13557, Q9UQM7

Gene Symbols:
Camk2a, Camk2b, CAMK2D, Camk2g

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human CaMK2 alpha around the phosphorylation site of Thr305.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-6457

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Antigen:
Phospho-CDK2 (Thr14)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDK2

Gene Alias:
A630093N05Rik; CDC28; CDC2A; cdc2-related protein kinase; CDK1; CDK2; Cdkn2; Cell division protein kinase 2; cyclin dependent kinase 2; cyclin dependent kinase 2-alpha; Cyclin-dependent kinase 2; EC 2.7.11.22; EC 2.7.11.23; kinase Cdc2; MPF; p33 protein kinase; p33(CDK2); p33CDK2; p34 protein kinase

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1017

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P24941

Gene Symbols:
CDK2

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human CDK2 around the phosphorylation site of Thr14 [EG (p-T)YG].

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-6458

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Antigen:
Phospho-CDKN1B (Thr198)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cdkn1b

Gene Alias:
AA408329; AI843786; Cdki1b; CDKN1B; CDKN4; CDN1B; cyclin dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor 1B (p27 Kip1); cyclin-dependent kinase inhibitor 1B (p27, Kip1); Cyclin-dependent kinase inhibitor p27; cyclin-dependent kinase inhibitor p27/Kip1; KIP1; MEN1B; MEN4; p27; P27 CDKN1B; p27(KIP1); p27Kip1; putative cyclin-dependent kinase inhibitor p27

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1027

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P46527

Gene Symbols:
Cdkn1b

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human CDKN1B/P27kip1 around the phosphorylation site of Thr198 [RRQ (p-T)].

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG