50-199-0067

Osteopontin Polyclonal Antibody, Rockland™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 50-199-0067-Each-of-1 In Stock ₹ 14,374.08

50-199-0067 - Each of 1

₹ 14,374.08

In Stock

Quantity

1

Base Price: ₹ 14,374.08

GST (18%): ₹ 2,587.334

Total Price: ₹ 16,961.414

Antigen

Osteopontin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SPP1

Gene Alias

2AR; 2b7; 44 kDa bone phosphoprotein; Apl-1; BNSP; Bone sialoprotein 1; Bsp; BSPI; Calcium oxalate crystal growth inhibitor protein; early T-lymphocyte activation 1; Early T-lymphocyte activation 1 protein; Eta; Eta-1; HGNC:11255; MGC110940; Minopontin; Nephropontin; Op; OPN; Opnl; OSP; Osteopontin; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; osteopontin-like protein; PSEC0156; Ric; Secreted phosphoprotein 1; secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); secreted phosphoprotein 1 variant 6; Sialoprotein (osteopontin); Spp1; Spp-1; SPP1/CALPHA1 fusion; urinar; Urinary stone protein; Uropontin

Host Species

Rabbit

Quantity

25 μL

Primary or Secondary

Primary

Target Species

Canine, Human, Mouse, Porcine, Rat

Product Type

Antibody

Applications

ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration

95 mg/mL

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.

P08721, P10451, P10923, P14287

Gene Symbols

SPP1

Immunogen

This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide, from the human osteopontin protein, conjugated to KLH using maleimide.

Regulatory Status

RUO

Gene ID (Entrez)

20750, 25353, 397087, 478471, 6696

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • Osteopontin is directed against human osteopontin
  • The antibody recognizes the full-length osteopontin protein (which runs at 66 kDa on westerns), as well as the C-terminal fragments of both thrombin and MMP-cleaved OPN
  • The 32 kDa MMP-cleaved C-fragment is recognized, but not the 40 kDa N-terminal fragment
  • Reactivity is reported to occur with osteopontin from swine, dog, mouse and rat
  • Osteopontin is an arginine-glycine-aspartic acid (RGD)-containing glycoprotein that interacts with integrins and CD44 as major receptors
  • It is a multifunctional protein involved in bone mineralization, cell adhesion, cell migration, chronic inflammatory disease and transformation
  • Proteolytic cleavage by thrombin and matrix metalloproteinases close to the integrin-binding Arg-Gly-Asp sequence modulates the function of OPN and its integrin binding properties
  • Thrombin-cleaved fragments of Osteopontin are overexpressed in malignant glial tumors and provide a molecular niche with survival advantage and provide a novel substrate for plasmin and cathepsin D.

Compare Similar Items

Show Difference

Img

Fischer Scientific

50-199-0067

--


Antigen:
Osteopontin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPP1

Gene Alias:
2AR; 2b7; 44 kDa bone phosphoprotein; Apl-1; BNSP; Bone sialoprotein 1; Bsp; BSPI; Calcium oxalate crystal growth inhibitor protein; early T-lymphocyte activation 1; Early T-lymphocyte activation 1 protein; Eta; Eta-1; HGNC:11255; MGC110940; Minopontin; Nephropontin; Op; OPN; Opnl; OSP; Osteopontin; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; osteopontin-like protein; PSEC0156; Ric; Secreted phosphoprotein 1; secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); secreted phosphoprotein 1 variant 6; Sialoprotein (osteopontin); Spp1; Spp-1; SPP1/CALPHA1 fusion; urinar; Urinary stone protein; Uropontin

Host Species:
Rabbit

Quantity:
25 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Porcine, Rat

Product Type:
Antibody

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
95 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
P08721, P10451, P10923, P14287

Gene Symbols:
SPP1

Immunogen:
This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide, from the human osteopontin protein, conjugated to KLH using maleimide.

Regulatory Status:
RUO

Gene ID (Entrez):
20750, 25353, 397087, 478471, 6696

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Rockland Immunochemicals

50-199-0069

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Antigen:
NOTCH 2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NOTCH2

Gene Alias:
AGS2; AI853703; HJCYS; hN2; Motch B; N2; N2ECD; N2ICD; Neurogenic locus notch homolog protein 2; Notch 2; Notch 2 extracellular truncation; Notch 2 intracellular domain; notch gene homolog 2; Notch homolog 2; Notch2

Host Species:
Rabbit

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Canine, Chimpanzee, Human

Product Type:
Antibody

Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
75 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.1% sodium azide; pH 7.2

Gene Accession No.:
Q04721

Gene Symbols:
NOTCH2

Immunogen:
This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide corresponding to an internal region near amino acid residues 2390-2415 of human Notch 2 (the total protein is 2471 aa). A residue of cysteine was added to the amino terminal end to facilitate coupling.

Regulatory Status:
RUO

Gene ID (Entrez):
457173, 483148, 4853

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-0073

--


Antigen:
NOTCH 2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NOTCH2

Gene Alias:
AGS2; AI853703; HJCYS; hN2; Motch B; N2; N2ECD; N2ICD; Neurogenic locus notch homolog protein 2; Notch 2; Notch 2 extracellular truncation; Notch 2 intracellular domain; notch gene homolog 2; Notch homolog 2; Notch2

Host Species:
Rabbit

Quantity:
25 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
80 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
Q04721

Gene Symbols:
NOTCH2

Immunogen:
This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide corresponding to amino acid residues of human Notch 2 located near the N-terminal sequence of the cleaved N intracellular domain (NICD).

Regulatory Status:
RUO

Gene ID (Entrez):
4853

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Rockland Immunochemicals

50-199-0074

--


Antigen:
Phospho-Myosin (Ser19, Ser20)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MYL12B

Gene Alias:
1500001M02Rik; 20 kDa myosin light chain; 2900073G15Rik; AI327049; AI838292; brain specific myosin regulatory light chain; C77744; C80200; Epididymis secretory protein Li 24; HEL-S-24; LC20; MLC2; MLC-2; MLC20; MLC-2A; MLC-2B; MLC-2C; MLCB; MLC-B; MRCL3; MRLC1; MRLC2; MRLC3; Mrlcb; MYL12A; Myl12b; MYL2B; MYL9; Mylc2b; Mylc2c; myosin light chain 12A; myosin light chain 12B; myosin light chain 9; myosin light chain, regulatory B; myosin light chain, regulatory B-like; myosin light chain, regulatory C; myosin regulatory light chain 1; Myosin regulatory light chain 12A; Myosin regulatory light chain 12B; myosin regulatory light chain 2; Myosin regulatory light chain 2, nonsarcomeric; Myosin regulatory light chain 2, smooth muscle isoform; Myosin regulatory light chain 20 kDa; Myosin regulatory light chain 2-A, smooth muscle isoform; Myosin regulatory light chain 2-B, smooth muscle isoform; myosin regulatory light chain 3; Myosin regulatory light chain 9; Myosin regulatory light chain MRLC1; Myosin regulatory light chain MRLC2; Myosin regulatory light chain MRLC3; Myosin regulatory light chain RLC-A; myosin regulatory light chain-B; Myosin regulatory light polypeptide 9; Myosin RLC; Myosin RLC-A; Myosin RLC-B; myosin, light chain 12A, regulatory, non-sarcomeric; myosin, light chain 12B, regulatory; myosin, light chain 9, regulatory; myosin, light polypeptide 9, regulatory; myosin, light polypeptide, regulatory, non-sarcomeric (20kD); Myrl2; NMDA receptor-interacting protein; RGD1309537; RLC; Rlc-a; RLC-B; RLC-C; SHUJUN-1

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
70 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
O14950, P19105, P24844

Gene Symbols:
MYL12A, MYL12B, MYL9

Immunogen:
Human Myosin Light Chain phospho peptide corresponding to a region near the amino terminus of the human smooth/non-muscle form of myosin regulatory light chain conjugated to Keyhole Limpet Hemocyanin (KLH).

Regulatory Status:
RUO

Gene ID (Entrez):
103910, 10398, 10627

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid