7191022

Osteopontin Polyclonal Antibody, Rockland™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Osteopontin

Applications

ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Canine, Human, Mouse, Porcine, Rat

Gene Accession No.

P08721, P10451, P10923, P14287

Gene ID (Entrez)

20750, 25353, 397087, 478471, 6696

Immunogen

This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide, from the human osteopontin protein, conjugated to KLH using maleimide.

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

SPP1

Concentration

95 mg/mL

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias

2AR; 2b7; 44 kDa bone phosphoprotein; Apl-1; BNSP; Bone sialoprotein 1; Bsp; BSPI; Calcium oxalate crystal growth inhibitor protein; early T-lymphocyte activation 1; Early T-lymphocyte activation 1 protein; Eta; Eta-1; HGNC:11255; MGC110940; Minopontin; Nephropontin; Op; OPN; Opnl; OSP; Osteopontin; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; osteopontin-like protein; PSEC0156; Ric; Secreted phosphoprotein 1; secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); secreted phosphoprotein 1 variant 6; Sialoprotein (osteopontin); Spp1; Spp-1; SPP1/CALPHA1 fusion; urinar; Urinary stone protein; Uropontin

Gene Symbols

SPP1

Primary or Secondary

Primary

Product Type

Antibody

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Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • Osteopontin is directed against human osteopontin
  • The antibody recognizes the full-length osteopontin protein (which runs at 66 kDa on westerns), as well as the C-terminal fragments of both thrombin and MMP-cleaved OPN
  • The 32 kDa MMP-cleaved C-fragment is recognized, but not the 40 kDa N-terminal fragment
  • Reactivity is reported to occur with osteopontin from swine, dog, mouse and rat
  • Osteopontin is an arginine-glycine-aspartic acid (RGD)-containing glycoprotein that interacts with integrins and CD44 as major receptors
  • It is a multifunctional protein involved in bone mineralization, cell adhesion, cell migration, chronic inflammatory disease and transformation
  • Proteolytic cleavage by thrombin and matrix metalloproteinases close to the integrin-binding Arg-Gly-Asp sequence modulates the function of OPN and its integrin binding properties
  • Thrombin-cleaved fragments of Osteopontin are overexpressed in malignant glial tumors and provide a molecular niche with survival advantage and provide a novel substrate for plasmin and cathepsin D.

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7191022

Rabbit Polyclonal Antibody...


Antigen:
Osteopontin

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Canine, Human, Mouse, Porcine, Rat

Gene Accession No.:
P08721, P10451, P10923, P14287

Gene ID (Entrez):
20750, 25353, 397087, 478471, 6696

Immunogen:
This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide, from the human osteopontin protein, conjugated to KLH using maleimide.

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
SPP1

Concentration:
95 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
2AR; 2b7; 44 kDa bone phosphoprotein; Apl-1; BNSP; Bone sialoprotein 1; Bsp; BSPI; Calcium oxalate crystal growth inhibitor protein; early T-lymphocyte activation 1; Early T-lymphocyte activation 1 protein; Eta; Eta-1; HGNC:11255; MGC110940; Minopontin; Nephropontin; Op; OPN; Opnl; OSP; Osteopontin; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; osteopontin-like protein; PSEC0156; Ric; Secreted phosphoprotein 1; secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); secreted phosphoprotein 1 variant 6; Sialoprotein (osteopontin); Spp1; Spp-1; SPP1/CALPHA1 fusion; urinar; Urinary stone protein; Uropontin

Gene Symbols:
SPP1

Primary or Secondary:
Primary

Product Type:
Antibody

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7191023

Rabbit Polyclonal Antibody...


Antigen:
Phospho-STAT3 (Tyr705)

Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P40763

Gene ID (Entrez):
6774

Immunogen:
__

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
STAT3

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
1110034C02Rik; acute phase response factor; Acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; BOS_19088; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; Signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT-3 protein; STAT3b1; STAT3b2; transcription factor; wu:fc15d02; wu:fl59g06; z-Stat3

Gene Symbols:
STAT3

Primary or Secondary:
Primary

Product Type:
Antibody

Img

Fischer Scientific

7191023

Rabbit Polyclonal Antibody...


Antigen:
Phospho-STAT3 (Tyr705)

Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P40763

Gene ID (Entrez):
6774

Immunogen:
__

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
STAT3

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
1110034C02Rik; acute phase response factor; Acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; BOS_19088; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; Signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT-3 protein; STAT3b1; STAT3b2; transcription factor; wu:fc15d02; wu:fl59g06; z-Stat3

Gene Symbols:
STAT3

Primary or Secondary:
Primary

Product Type:
Antibody

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7191024

Rabbit Polyclonal Antibody...


Antigen:
NEDD4

Applications:
ELISA, Immunofluorescence, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Equine, Human, Rhesus Monkey

Gene Accession No.:
P46934

Gene ID (Entrez):
100054735, 4734, 699550

Immunogen:
__

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
NEDD4

Concentration:
0.64 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
AA959633; AL023035; AU019897; Cell proliferation-inducing gene 53 protein; E3 ubiquitin-protein ligase NEDD4; E430025J12Rik; HECT-type E3 ubiquitin transferase NEDD4; Kiaa0093; mKIAA0093; Nedd4; Nedd-4; Nedd4-1; Nedd4a; Neural precursor cell expressed developmentally down-regulated protein 4; neural precursor cell expressed, developmentally down-regulated 4; neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase; neural precursor cell expressed, developmentally down-regulated gene 4; neural precursor cell expressed, developmentally down-regulated gene 4a; neural precursor cell expressed, developmentally down-regulted gene 4; OTTHUMP00000217840; OTTHUMP00000217841; OTTHUMP00000217842; PIG53; receptor-potentiating factor 1; RPF1

Gene Symbols:
NEDD4

Primary or Secondary:
Primary

Product Type:
Antibody