50-199-1850

Phospho-HMGN (Ser20, Ser24)Rabbit anti-Human, Polyclonal, Rockland™

Manufacturer: Rockland Immunochemicals

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Pack Size SKU Availability Price
Each of 1 50-199-1850-Each-of-1 In Stock ₹ 50,884.24

50-199-1850 - Each of 1

₹ 50,884.24

In Stock

Quantity

1

Base Price: ₹ 50,884.24

GST (18%): ₹ 9,159.163

Total Price: ₹ 60,043.403

Antigen

Phospho-HMGN (Ser20, Ser24)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HMGN1

Gene Alias

BOS_1365; FLJ27265; FLJ31471; high mobility group nucleosomal binding domain 1; high mobility group nucleosome binding domain 1; High mobility group nucleosome-binding domain-containing protein 1; high mobility group protein 14; high-mobility group (nonhistone chromosomal) protein 14; high-mobility group nucleosome binding 1; high-mobility group nucleosome binding domain 1; high-mobility group nucleosome-binding domain-containing protein 1; HMG 14; Hmg14; Hmg-14; HMGN 1; HMGN1; MGC104230; MGC117425; Non-histone chromosomal protein HMG-14; nonhistone chromosomal protein HMG-14

Host Species

Rabbit

Regulatory Status

RUO

Gene ID (Entrez)

3150

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1.2 mg/mL

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.

P05114

Gene Symbols

HMGN1

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

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Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • This affinity-purified antibody is directed against phosphorylated human HMGN protein at pS20 and pS24 residues (other HMGN proteins have this conserved sequence but at other residue positions)
  • Reactivity occurs against human HMGN pS20/pS24 proteins and the antibody is specific for the phosphorylated form of the proteins
  • Reactivity is seen against HMGN1 and HMGN2
  • HMGN3 is also likely reactive although not tested
  • Reactivity with non-phosphorylated human HMGNs is minimal by ELISA
  • A BLAST analysis was used to suggest cross reactivity with HMGN proteins from Xenopus, chicken, mouse, bovine, dog, orangutan, rat and swine based on 100% homology with the immunizing sequence
  • Reactivity against homologues from other sources is not known
  • The high-mobility group (HMG) proteins 14 and 17 are abundant chromosomal proteins that bind to nucleosomes and enhance transcription
  • HMG-14 and HMG-17 also function as architectural elements, which alter the structure of the chromatin fiber and enhance transcription from chromatin templates
  • HMG-14/17 proteins modify the nucleosomal organization of the 30 nm chromatin fiber and mediate the unfolding of the higher order chromatin structure thereby facilitating access to the underlying DNA sequence
  • Clustering of architectural elements, such as HMG proteins and linker histone subtypes into distinct domains, may lead to structural and functional heterogeneity along the chromatin fiber
  • In addition, HMG-14 and HMG-17 have been identified as constitutive components of mouse oocyte and embryonic chromatin that establish a link between the structure of embryonic chromatin and the normal progression of embryonic development.

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Rockland Immunochemicals

50-199-1850

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Antigen:
Phospho-HMGN (Ser20, Ser24)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HMGN1

Gene Alias:
BOS_1365; FLJ27265; FLJ31471; high mobility group nucleosomal binding domain 1; high mobility group nucleosome binding domain 1; High mobility group nucleosome-binding domain-containing protein 1; high mobility group protein 14; high-mobility group (nonhistone chromosomal) protein 14; high-mobility group nucleosome binding 1; high-mobility group nucleosome binding domain 1; high-mobility group nucleosome-binding domain-containing protein 1; HMG 14; Hmg14; Hmg-14; HMGN 1; HMGN1; MGC104230; MGC117425; Non-histone chromosomal protein HMG-14; nonhistone chromosomal protein HMG-14

Host Species:
Rabbit

Regulatory Status:
RUO

Gene ID (Entrez):
3150

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.2 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
P05114

Gene Symbols:
HMGN1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Img

Rockland Immunochemicals

50-199-1851

--


Antigen:
NOXO1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NOXO1

Gene Alias:
2310034C04Rik; hslt; MGC20258; NADPH oxidase organizer 1; NADPH oxidase regulatory protein; Nox organizer 1; Noxo1; Nox-organizing protein 1; P41NOX; P41NOXA; P41NOXB; P41NOXC; regulatory protein P41NOX; SH3 and PX domain-containing protein 5; SH3PXD5; Snx28; Sorting nexin-28

Host Species:
Rabbit

Regulatory Status:
RUO

Gene ID (Entrez):
124056, 468090

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
Q8NFA2

Gene Symbols:
NOXO1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Chimpanzee, Human

Product Type:
Antibody

Img

Rockland Immunochemicals

50-199-1852

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Antigen:
EGFR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EGFR

Gene Alias:
2.7.10.1; 9030024J15Rik; AI552599; avian erythroblastic leukemia viral (v-erbB) oncogene homolog; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; EC 2.7.10.1; egf receptor; Egfr; EGFR-related peptide; Epidermal growth factor receptor; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); ERBB; ERBB1; ErbB-1; erb-b2 receptor tyrosine kinase 1; Errb1; Errp; HER1; kinase EGFR; mENA; NISBD2; Oncogene ERBB; PIG61; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1; Urogastrone; wa2; wa-2; Wa5; waved 2

Host Species:
Rabbit

Regulatory Status:
RUO

Gene ID (Entrez):
13649, 1956, 24329

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Western Blot

Concentration:
0.99 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
P00533, Q01279

Gene Symbols:
EGFR

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Img

Rockland Immunochemicals

50-199-1853

--


Antigen:
CHK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; Checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; Chek1; Chk1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; Serine/threonine-protein kinase Chk1; Synoviolin

Host Species:
Rabbit

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunoprecipitation, Western Blot

Concentration:
0.73 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Yeast

Product Type:
Antibody