50-199-2007

RRM2B p53R2 Polyclonal Antibody, Rockland™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-199-2007-Each-of-1 In Stock ₹ 14,374.08

50-199-2007 - Each of 1

₹ 14,374.08

In Stock

Quantity

1

Base Price: ₹ 14,374.08

GST (18%): ₹ 2,587.334

Total Price: ₹ 16,961.414

Antigen

RRM2B p53R2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Rrm2b

Gene Alias

MTDPS8A; MTDPS8B; p53-inducible ribonucleotide reductase small subunit 2 homolog; p53-inducible ribonucleotide reductase small subunit 2 short form beta; p53-inducible ribonucleotide reductase small subunit 2-like protein; P53r2; Ribonucleoside-diphosphate reductase subunit M2 B; ribonucleotide reductase M2 B (TP53 inducible); ribonucleotide reductase regulatory TP53 inducible subunit M2B; Rrm2b; TP53-inducible ribonucleotide reductase M2 B

Host Species

Rabbit

Regulatory Status

RUO

Gene ID (Entrez)

50484

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration

0.82 mg/mL

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.

Q7LG56

Gene Symbols

Rrm2b

Quantity

25 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

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Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • Anti-Human RRM2B/p53R2 is directed against RRM2B and reacts with the RRM2B from human tissues
  • Based on sequence we expect this antibody to react as well with RRM2B from other species
  • Based on 100% homology to the immunizing sequence, one may expect reactivity to chimpanzee and orangutan; based on 93% homology, reactivity to macaque, and 92% to pig and Drosophila
  • The p53 tumor-suppressor gene integrates numerous signals that control cell life and death
  • Several novel molecules involved in p53 signaling, including p53R2, Chk2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered
  • p53R2 is a p53 inducible gene that contains a p53 binding sequence and encodes a subunit of the enzyme ribonucleotide reductase
  • p53R2 is induced by the reagents, ultraviolet and -gamma-irradiation that cause DNA damages
  • The product of p53R2 gene is directly involved in the p53 checkpoint for repair of damaged DNA
  • The isoform of the p53 family member p73 also induces p53R2 expression
  • p53R2 is an important target of p53 for tumor suppression.

Compare Similar Items

Show Difference

Img

Fischer Scientific

50-199-2007

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Antigen:
RRM2B p53R2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Rrm2b

Gene Alias:
MTDPS8A; MTDPS8B; p53-inducible ribonucleotide reductase small subunit 2 homolog; p53-inducible ribonucleotide reductase small subunit 2 short form beta; p53-inducible ribonucleotide reductase small subunit 2-like protein; P53r2; Ribonucleoside-diphosphate reductase subunit M2 B; ribonucleotide reductase M2 B (TP53 inducible); ribonucleotide reductase regulatory TP53 inducible subunit M2B; Rrm2b; TP53-inducible ribonucleotide reductase M2 B

Host Species:
Rabbit

Regulatory Status:
RUO

Gene ID (Entrez):
50484

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
0.82 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
Q7LG56

Gene Symbols:
Rrm2b

Quantity:
25 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Img

Fischer Scientific

50-199-2008

--


Antigen:
GST

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
Glutathione-S-Transferase; GST protein; GST Tag

Host Species:
Rabbit

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
__

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Quantity:
1 mg

Primary or Secondary:
Primary

Target Species:
__

Product Type:
Antibody

Img

Fischer Scientific

50-199-2009

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Antigen:
BrdU

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
5-Bromo-2-deoxyuridine; Bromodeoxyuridine

Host Species:
Rabbit

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
1.1 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
__

Product Type:
Antibody

Img

Bioworld

50-199-201

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Antigen:
__

Classification:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

Form:
__

Applications:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Quantity:
__

Primary or Secondary:
__

Target Species:
__

Product Type:
__