7191110
RRM2B p53R2 Polyclonal Antibody, Rockland™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
RRM2B p53R2
Applications
ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q7LG56
Gene ID (Entrez)
50484
Primary or Secondary
Primary
Product Type
Antibody
Concentration
0.82 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias
MTDPS8A; MTDPS8B; p53-inducible ribonucleotide reductase small subunit 2 homolog; p53-inducible ribonucleotide reductase small subunit 2 short form beta; p53-inducible ribonucleotide reductase small subunit 2-like protein; P53r2; Ribonucleoside-diphosphate reductase subunit M2 B; ribonucleotide reductase M2 B (TP53 inducible); ribonucleotide reductase regulatory TP53 inducible subunit M2B; Rrm2b; TP53-inducible ribonucleotide reductase M2 B
Gene Symbols
Rrm2b
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
Rrm2b
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- Anti-Human RRM2B/p53R2 is directed against RRM2B and reacts with the RRM2B from human tissues
- Based on sequence we expect this antibody to react as well with RRM2B from other species
- Based on 100% homology to the immunizing sequence, one may expect reactivity to chimpanzee and orangutan; based on 93% homology, reactivity to macaque, and 92% to pig and Drosophila
- The p53 tumor-suppressor gene integrates numerous signals that control cell life and death
- Several novel molecules involved in p53 signaling, including p53R2, Chk2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered
- p53R2 is a p53 inducible gene that contains a p53 binding sequence and encodes a subunit of the enzyme ribonucleotide reductase
- p53R2 is induced by the reagents, ultraviolet and -gamma-irradiation that cause DNA damages
- The product of p53R2 gene is directly involved in the p53 checkpoint for repair of damaged DNA
- The isoform of the p53 family member p73 also induces p53R2 expression
- p53R2 is an important target of p53 for tumor suppression.
Compare Similar Items
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Antigen: RRM2B p53R2
Applications: ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q7LG56
Gene ID (Entrez): 50484
Primary or Secondary: Primary
Product Type: Antibody
Concentration: 0.82 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: MTDPS8A; MTDPS8B; p53-inducible ribonucleotide reductase small subunit 2 homolog; p53-inducible ribonucleotide reductase small subunit 2 short form beta; p53-inducible ribonucleotide reductase small subunit 2-like protein; P53r2; Ribonucleoside-diphosphate reductase subunit M2 B; ribonucleotide reductase M2 B (TP53 inducible); ribonucleotide reductase regulatory TP53 inducible subunit M2B; Rrm2b; TP53-inducible ribonucleotide reductase M2 B
Gene Symbols: Rrm2b
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: Rrm2b
Antigen:
RRM2B p53R2
Applications:
ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q7LG56
Gene ID (Entrez):
50484
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
0.82 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
MTDPS8A; MTDPS8B; p53-inducible ribonucleotide reductase small subunit 2 homolog; p53-inducible ribonucleotide reductase small subunit 2 short form beta; p53-inducible ribonucleotide reductase small subunit 2-like protein; P53r2; Ribonucleoside-diphosphate reductase subunit M2 B; ribonucleotide reductase M2 B (TP53 inducible); ribonucleotide reductase regulatory TP53 inducible subunit M2B; Rrm2b; TP53-inducible ribonucleotide reductase M2 B
Gene Symbols:
Rrm2b
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
Rrm2b
Antigen: ATDC
Applications: Dot Blot, ELISA, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Bovine, Chimpanzee, Equine, Human, Rhesus Monkey
Gene Accession No.: Q14134
Gene ID (Entrez): 100071461, 23650, 451615, 525062, 705796
Primary or Secondary: Primary
Product Type: Antibody
Concentration: 0.67 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: 1110047J21Rik; 2810431N19Rik; 4732461M22Rik; AI119726; Ataxia telangiectasia group D-associated protein; ataxia-telangiectasia group D-associated protein; ATDC; FLJ36085; TRIM29; tripartite motif containing 29; tripartite motif protein 29; tripartite motif protein TRIM29; tripartite motif-containing 29; Tripartite motif-containing protein 29
Gene Symbols: Trim29
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: Trim29
Antigen:
ATDC
Applications:
Dot Blot, ELISA, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Bovine, Chimpanzee, Equine, Human, Rhesus Monkey
Gene Accession No.:
Q14134
Gene ID (Entrez):
100071461, 23650, 451615, 525062, 705796
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
0.67 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
1110047J21Rik; 2810431N19Rik; 4732461M22Rik; AI119726; Ataxia telangiectasia group D-associated protein; ataxia-telangiectasia group D-associated protein; ATDC; FLJ36085; TRIM29; tripartite motif containing 29; tripartite motif protein 29; tripartite motif protein TRIM29; tripartite motif-containing 29; Tripartite motif-containing protein 29
Gene Symbols:
Trim29
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
Trim29
Antigen: Trypsin
Applications: ELISA, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Bovine
Gene Accession No.: __
Gene ID (Entrez): 282603, 615026
Primary or Secondary: Primary
Product Type: Antibody
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: Alpha-trypsin chain 1; Alpha-trypsin chain 2; Anionic trypsin I; Anionic trypsin II; Anionic trypsin-1; Anionic trypsin-2; Anionic trypsinogen; Beta-trypsin; Cationic trypsinogen; digestive zymogen; MGC120175; MGC149362; nonfunctional trypsin 1; pancreatic trypsin 1; pancreatic trypsin 2; pancreatic trypsin II; Pretrypsinogen I; Pretrypsinogen II; Protease Serine 1; protease serine 2 preproprotein; protease, serine 1; protease, serine 1 (trypsin 1); protease, serine 2; protease, serine, 1; protease, serine, 1 (trypsin 1); protease, serine, 2; protease, serine, 2 (trypsin 2); Prss1; PRSS2; PTRYI; Ptryss2; RATPTRYI; Serine protease 1; Serine protease 2; Ta; TCR V beta 4.1; Tesp4; TRP1; TRY1; Try-1; TRY2; TRY4; TRY8; Trygn16; TRYP; TRYP1; TRYP2; TRYP8; trypsin 1; trypsin 2; Trypsin I; Trypsin II; Trypsin-1; Trypsin-2; trypsinogen 1; trypsinogen 16; trypsinogen 2; trypsinogen 20; trypsinogen A
Gene Symbols: PRSS1, PRSS2
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene: PRSS2
Antigen:
Trypsin
Applications:
ELISA, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Bovine
Gene Accession No.:
__
Gene ID (Entrez):
282603, 615026
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
Alpha-trypsin chain 1; Alpha-trypsin chain 2; Anionic trypsin I; Anionic trypsin II; Anionic trypsin-1; Anionic trypsin-2; Anionic trypsinogen; Beta-trypsin; Cationic trypsinogen; digestive zymogen; MGC120175; MGC149362; nonfunctional trypsin 1; pancreatic trypsin 1; pancreatic trypsin 2; pancreatic trypsin II; Pretrypsinogen I; Pretrypsinogen II; Protease Serine 1; protease serine 2 preproprotein; protease, serine 1; protease, serine 1 (trypsin 1); protease, serine 2; protease, serine, 1; protease, serine, 1 (trypsin 1); protease, serine, 2; protease, serine, 2 (trypsin 2); Prss1; PRSS2; PTRYI; Ptryss2; RATPTRYI; Serine protease 1; Serine protease 2; Ta; TCR V beta 4.1; Tesp4; TRP1; TRY1; Try-1; TRY2; TRY4; TRY8; Trygn16; TRYP; TRYP1; TRYP2; TRYP8; trypsin 1; trypsin 2; Trypsin I; Trypsin II; Trypsin-1; Trypsin-2; trypsinogen 1; trypsinogen 16; trypsinogen 2; trypsinogen 20; trypsinogen A
Gene Symbols:
PRSS1, PRSS2
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene:
PRSS2
Antigen: Acetyl-p53 (Lys292)
Applications: Dot Blot, ELISA, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P04637
Gene ID (Entrez): 7157
Primary or Secondary: Primary
Product Type: Antibody
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: 53BP1; Antigen NY-CO-13; bbl; BCC7; bfy; bhy; BOS_18908; Cellular tumor antigen p53; Cys 51 Stop; EGK_08142; FLJ92943; HGNC11998; I79_002739; LFS1; Li-Fraumeni syndrome; m53BP1; murine p53-binding protein; mutant p53; mutant tumor protein 53; OTTMUSP00000006194; p44; P53; p53 cellular tumor antigen; p53 tumor suppressor; p53 tumor suppressor phosphoprotein; p53-binding protein 1; p53BP1; Phosphoprotein p53; tp53; tp53.L; TP53-binding protein 1; Tp53bp1; transformation related protein 53; transformation related protein 53 binding protein 1; transformation related protein 53 binding-protein 1; transformation-related protein 53; Trp248; Trp53; Trp53bp1; tumor protein 53; tumor protein p53; tumor protein p53 (Li-Fraumeni syndrome); tumor protein p53 L homeolog; Tumor suppressor p53; tumor suppressor p53-binding protein 1; tumor suppressor protein p53; tumor supressor p53; Tumour Protein p53; XELAEV_180196761mg; Xp53; Xrel3
Gene Symbols: Tp53
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: Tp53
Antigen:
Acetyl-p53 (Lys292)
Applications:
Dot Blot, ELISA, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P04637
Gene ID (Entrez):
7157
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
53BP1; Antigen NY-CO-13; bbl; BCC7; bfy; bhy; BOS_18908; Cellular tumor antigen p53; Cys 51 Stop; EGK_08142; FLJ92943; HGNC11998; I79_002739; LFS1; Li-Fraumeni syndrome; m53BP1; murine p53-binding protein; mutant p53; mutant tumor protein 53; OTTMUSP00000006194; p44; P53; p53 cellular tumor antigen; p53 tumor suppressor; p53 tumor suppressor phosphoprotein; p53-binding protein 1; p53BP1; Phosphoprotein p53; tp53; tp53.L; TP53-binding protein 1; Tp53bp1; transformation related protein 53; transformation related protein 53 binding protein 1; transformation related protein 53 binding-protein 1; transformation-related protein 53; Trp248; Trp53; Trp53bp1; tumor protein 53; tumor protein p53; tumor protein p53 (Li-Fraumeni syndrome); tumor protein p53 L homeolog; Tumor suppressor p53; tumor suppressor p53-binding protein 1; tumor suppressor protein p53; tumor supressor p53; Tumour Protein p53; XELAEV_180196761mg; Xp53; Xrel3
Gene Symbols:
Tp53
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
Tp53