50-199-2714

MBD2 Polyclonal Antibody, Active Motif™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-199-2714-Each-of-1 In Stock ₹ 12,834.00

50-199-2714 - Each of 1

₹ 12,834.00

In Stock

Quantity

1

Base Price: ₹ 12,834.00

GST (18%): ₹ 2,310.12

Total Price: ₹ 15,144.12

Antigen

MBD2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Mbd2

Gene Alias

Demethylase; DKFZp586O0821; DMTase; MBD2; MBD2a; methyl-CpG binding domain protein 2; Methyl-CpG-binding domain protein 2; Methyl-CpG-binding protein MBD2; NY-CO-41

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8932

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

Lot-Specific

Formulation

70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Accession No.

Q9UBB5

Gene Symbols

Mbd2

Immunogen

This MBD2 antibody was raised against a synthetic peptide corresponding to human MBD2.

Quantity

10 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Heterochromatin protein-1 (HP1) is a methyl-lysine binding protein localized at heterochromatin sites, where it mediates gene silencing
  • It has been shown that mammalian methyltransferases that selectively methylate histone H3 on lysine-9 generate a binding site for HP1 proteins, a family of heterochromatic adaptor molecules implicated in both gene silencing and supranucleosomal chromatin structure
  • High-affinity in vitro recognition of a methylated histone H3 peptide by HP1 requires a functional chromodomain
  • Thus, the HP1 chromodomain is a specific interaction motif for the methyl epitope on lysine-9 of histone H3
  • In vivo, heterochromatin association of HP1 proteins is lost in Suv39h double-null primary mouse fibroblasts but is restored after reintroduction of a catalytically active SUV39H1 HMTase.

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Fischer Scientific

50-199-2714

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Antigen:
MBD2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mbd2

Gene Alias:
Demethylase; DKFZp586O0821; DMTase; MBD2; MBD2a; methyl-CpG binding domain protein 2; Methyl-CpG-binding domain protein 2; Methyl-CpG-binding protein MBD2; NY-CO-41

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8932

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
Lot-Specific

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Accession No.:
Q9UBB5

Gene Symbols:
Mbd2

Immunogen:
This MBD2 antibody was raised against a synthetic peptide corresponding to human MBD2.

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

50-199-2717

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Antigen:
HIRA

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
HIRA

Gene Alias:
AA138857; D16Ertd95e; DGCR1; DiGeorge critical region gene 1; Gm15797; HIR; HIR histone cell cycle regulation defective homolog A; Hira; histone cell cycle regulation defective homolog A; histone cell cycle regulation defective homolog A (S. cerevisiae); histone cell cycle regulator; N28177; OTTMUSG00000026264; Protein HIRA; TUP1; TUP1-like enhancer of split gene 1; TUP1-like enhancer of split protein 1; Tuple1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
15260, 7290

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Accession No.:
P54198, Q61666

Gene Symbols:
HIRA

Immunogen:
This HIRA antibody was raised against a GST-fusion protein containing residues 421-729 of human HIRA.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

50-199-2718

--


Antigen:
HIRA

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
HIRA

Gene Alias:
AA138857; D16Ertd95e; DGCR1; DiGeorge critical region gene 1; Gm15797; HIR; HIR histone cell cycle regulation defective homolog A; Hira; histone cell cycle regulation defective homolog A; histone cell cycle regulation defective homolog A (S. cerevisiae); histone cell cycle regulator; N28177; OTTMUSG00000026264; Protein HIRA; TUP1; TUP1-like enhancer of split gene 1; TUP1-like enhancer of split protein 1; Tuple1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
15260, 7290

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Accession No.:
P54198, Q61666

Gene Symbols:
HIRA

Immunogen:
This HIRA antibody was raised against a GST-fusion protein containing residues 421-729 of human HIRA.

Quantity:
10 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

50-199-2721

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Antigen:
Phospho-RNA pol II CTD (Ser2)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
POLR2A

Gene Alias:
220kDa; AW321876; DNA polymerase alpha 1 catalytic subunit; DNA polymerase alpha 1, 180 kDa; DNA polymerase alpha 1, catalytic subunit; DNA polymerase alpha catalytic subunit; DNA polymerase alpha catalytic subunit p180; DNA polymerase alpha p180 subunit; DNA polymerase alpha subunit I; DNA polymerase epsilon catalytic subunit; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; DUN2; EC 2.7.7.6; G7a/Bat6Hom; hRPB220; hsRPB1; I79_002751; I79_016081; MGC75453; N0825; NSX; p180; Pol II S2p; POL2; Pola; POLA1; POLR2; Polr2a; POLRA; polymerase (DNA directed), alpha 1; polymerase (DNA directed), alpha 1, catalytic subunit; polymerase (DNA) alpha 1, catalytic subunit; polymerase (DNA-directed), alpha (70kD); Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; POLYMERASE II; polymerase, alpha 1; RNA; RNA POL2; RNA polymerase II 1; RNA polymerase II largest subunit; RNA polymerase II subunit A; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RP02; RPB1; RPB220; RPBh1; Rpii215; RpIILS; RPO2; RPO21; Rpo2-1; RPOL2; SUA8; YNL262W

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5422, 5430

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Dot Blot, Immunoprecipitation, Western Blot

Concentration:
Lot-Specific

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Accession No.:
P09884, P24928

Gene Symbols:
POLA1, POLR2A

Immunogen:
This RNA pol II CTD phospho Ser2 antibody was raised against a peptide containing the RNA Pol II CTD sequence phosphorylated at serine 2.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG