50-199-2910

MBD1 Polyclonal Antibody, Active Motif™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-199-2910-Each-of-1 In Stock ₹ 12,834.00

50-199-2910 - Each of 1

₹ 12,834.00

In Stock

Quantity

1

Base Price: ₹ 12,834.00

GST (18%): ₹ 2,310.12

Total Price: ₹ 15,144.12

Antigen

MBD1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MBD1

Gene Alias

CXXC3; CXXC-type zinc finger protein 3; Mbd1; methyl-CpG binding domain protein 1; methyl-CpG binding domain protein 1 isoform PCM1; Methyl-CpG-binding domain protein 1; Methyl-CpG-binding protein MBD1; PCM1; Protein containing methyl-CpG-binding domain 1; RFT; the regulator of fibroblast growth factor 2 (FGF-2) transcription

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4152

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

Lot-Specific

Formulation

70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Accession No.

Q9UIS9

Gene Symbols

MBD1

Immunogen

This MBD1 antibody was raised against a peptide within the C-terminal region of human MBD1.

Quantity

10 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Fischer Scientific

50-199-2909

--

Img

Fischer Scientific

50-199-2714

--

Img

Fischer Scientific

50-199-2713

--

Img

Fischer Scientific

50-199-3468

--

Img

Fischer Scientific

50-199-3467

--

Img

Fischer Scientific

50-199-2896

--

Img

Fischer Scientific

50-199-2895

--

Img

Fischer Scientific

50-199-3535

--

Description

  • Methyl-CpG-binding domain protein 1 (MBD1) is a member of a family of mammalian proteins that specifically bind methylated regions of DNA
  • It is a transcriptional repressor that binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides
  • Binding is abolished by the presence of 7-mG that is produced by DNA damage by methylmethanesulfonate (MMS)
  • MBD1 acts as a transcriptional repressor and plays a role in gene silencing by recruiting AFT7IP, which in turn recruits factors such as the histone methyltransferase SETDB1
  • Isoform 1 and isoform 2 can also repress transcription from unmethylated promoters.

Compare Similar Items

Show Difference

Img

Fischer Scientific

50-199-2910

--


Antigen:
MBD1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MBD1

Gene Alias:
CXXC3; CXXC-type zinc finger protein 3; Mbd1; methyl-CpG binding domain protein 1; methyl-CpG binding domain protein 1 isoform PCM1; Methyl-CpG-binding domain protein 1; Methyl-CpG-binding protein MBD1; PCM1; Protein containing methyl-CpG-binding domain 1; RFT; the regulator of fibroblast growth factor 2 (FGF-2) transcription

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4152

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
Lot-Specific

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Accession No.:
Q9UIS9

Gene Symbols:
MBD1

Immunogen:
This MBD1 antibody was raised against a peptide within the C-terminal region of human MBD1.

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

50-199-2911

--


Antigen:
PGC1-beta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PPARGC1B

Gene Alias:
__

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
133522

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
Lot-Specific

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Accession No.:
Q86YN6

Gene Symbols:
PPARGC1B

Immunogen:
This PGC1-beta antibody antibody was raised against a peptide within the N-terminal region of human PGC1-beta.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

50-199-2912

--


Antigen:
PGC1-beta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PPARGC1B

Gene Alias:
__

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
133522

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
Lot-Specific

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Accession No.:
Q86YN6

Gene Symbols:
PPARGC1B

Immunogen:
This PGC1-beta antibody antibody was raised against a peptide within the N-terminal region of human PGC1-beta.

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

50-199-2913

--


Antigen:
Ubn1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
UBN1

Gene Alias:
1110029L11Rik; 2610108L02Rik; AA673476; AW124741; HIRA-binding protein; Protein VT4; ubinuclein 1; Ubinuclein-1; Ubiquitously expressed nuclear protein; Ubn1; VT; VT4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
29855

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
Lot-Specific

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Accession No.:
Q9NPG3

Gene Symbols:
UBN1

Immunogen:
This Ubinuclein antibody was raised against a recombinant protein corresponding to amino acids 1-345 of human Ubn1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG