51-033-180
CD33 Monoclonal Antibody (9A11-CD33), Alexa Fluor™ 647, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 51-033-180-Each | In Stock | ₹ 12,889.61 |
51-033-180 - Each
In Stock
Quantity
1
Base Price: ₹ 12,889.61
GST (18%): ₹ 2,320.13
Total Price: ₹ 15,209.74
Antigen
CD33
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.
Q63994
Gene Symbols
CD33
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12489
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
9A11-CD33
Conjugate
Alexa Fluor 647
Gene
CD33
Gene Alias
CD33, CD33 antigen, CD33 antigen (gp67), CD33 molecule, CD33 molecule transcript, FLJ00391, gp67, Myeloid cell surface antigen CD33, p67, sialic acid binding Ig-like lectin 3, sialic acid-binding Ig-like lectin 3, SIGLEC3, Siglec-3
Host Species
Rat
Quantity
25 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG1 κ
Description
- Description: This monoclonal antibody 9A11-CD33 reacts with mouse CD33, also known as Siglec3 and gp67
- CD33 belongs to the sialic acid-binding immunoglobulin lectins (Siglec) family that binds to sialic acid-containing glycans on cell surface glycoproteins and glycolipids on mammalian cells
- Mouse CD33 binds to short O-linked glycans of certain mucins and sialyl-Tn epitopes
- Mouse CD33 is expressed by mature granulocytes, immature myeloid cells, and microglia
- Unlike human CD33, mouse CD33 lacks a cytoplasmic ITIM domain and exists as two splice variants that have different cytoplasmic tails
- In microglia, CD33 inhibits the phagocytosis of toxic amyloid beta
- Clone 9A11 has been used to characterize mouse CD33 surface expression and function
- <a href=https://www.ncbi.nlm.nih.gov/pubmed/31925286>View Article</a>
- Applications Reported: This 9A11-CD33 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This 9A11-CD33 antibody has been tested by flow cytometric analysis of mouse splenocytes
- This may be used at less than or equal to 0.125 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Excitation: 633-647 nm; Emission: 668 nm; Laser: Red Laser CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family
- It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies, and these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface
- CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia
- Further, CD33 is found on granulocyte and macrophage precursors in the bone marrow, but is not on pluripotent stem cells
- CD33 is also expressed on, and is a useful marker for, peripheral monocytes
- CD33 is useful for distinguishing myelogenous leukemia cells from lymphoid or erythroid leukemias
- Diseases associated with CD43 dysfunction include gallbladder lymphoma and extracutaneous mastocytoma.
Compare Similar Items
Show Difference
Antigen: CD33
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.: Q63994
Gene Symbols: CD33
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12489
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 9A11-CD33
Conjugate: Alexa Fluor 647
Gene: CD33
Gene Alias: CD33, CD33 antigen, CD33 antigen (gp67), CD33 molecule, CD33 molecule transcript, FLJ00391, gp67, Myeloid cell surface antigen CD33, p67, sialic acid binding Ig-like lectin 3, sialic acid-binding Ig-like lectin 3, SIGLEC3, Siglec-3
Host Species: Rat
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD33
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.:
Q63994
Gene Symbols:
CD33
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12489
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
9A11-CD33
Conjugate:
Alexa Fluor 647
Gene:
CD33
Gene Alias:
CD33, CD33 antigen, CD33 antigen (gp67), CD33 molecule, CD33 molecule transcript, FLJ00391, gp67, Myeloid cell surface antigen CD33, p67, sialic acid binding Ig-like lectin 3, sialic acid-binding Ig-like lectin 3, SIGLEC3, Siglec-3
Host Species:
Rat
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD33
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.: Q63994
Gene Symbols: CD33
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12489
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 9A11-CD33
Conjugate: Alexa Fluor 647
Gene: CD33
Gene Alias: CD33, CD33 antigen, CD33 antigen (gp67), CD33 molecule, CD33 molecule transcript, FLJ00391, gp67, Myeloid cell surface antigen CD33, p67, sialic acid binding Ig-like lectin 3, sialic acid-binding Ig-like lectin 3, SIGLEC3, Siglec-3
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD33
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.:
Q63994
Gene Symbols:
CD33
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12489
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
9A11-CD33
Conjugate:
Alexa Fluor 647
Gene:
CD33
Gene Alias:
CD33, CD33 antigen, CD33 antigen (gp67), CD33 molecule, CD33 molecule transcript, FLJ00391, gp67, Myeloid cell surface antigen CD33, p67, sialic acid binding Ig-like lectin 3, sialic acid-binding Ig-like lectin 3, SIGLEC3, Siglec-3
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD45
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: P08575
Gene Symbols: PTPRC
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5788
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: HI30
Conjugate: Alexa Fluor 647
Gene: PTPRC
Gene Alias: B220, cd45, CD45 antigen, CD45 antigen isoform 1 precursor, CD45 antigen isoform 2 precursor, CD45 antigen isoform 3 precursor, CD45 antigen isoform 4 precursor, CD45 antigen isoform 5 precursor, CD45 antigen isoform 6 precursor, CD45R, GP180, Lca, L-CA, leucocyte common antigen, leukocyte common antigen, leukocyte common antigen A, leukocyte common antigen B, leukocyte common antigen, CD45, loc, LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C, LY5, Ly-5, lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, membrane tyrosine phosphatase, protein tyrosine phosphatase lambda, protein tyrosine phosphatase receptor type C, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, Protein tyrosine phosphatase, receptor-type, c polypeptide, protein tyrosine phosphatase, alternatively spliced, Ptprc, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen, T220 and B220
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD45
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
P08575
Gene Symbols:
PTPRC
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5788
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
HI30
Conjugate:
Alexa Fluor 647
Gene:
PTPRC
Gene Alias:
B220, cd45, CD45 antigen, CD45 antigen isoform 1 precursor, CD45 antigen isoform 2 precursor, CD45 antigen isoform 3 precursor, CD45 antigen isoform 4 precursor, CD45 antigen isoform 5 precursor, CD45 antigen isoform 6 precursor, CD45R, GP180, Lca, L-CA, leucocyte common antigen, leukocyte common antigen, leukocyte common antigen A, leukocyte common antigen B, leukocyte common antigen, CD45, loc, LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C, LY5, Ly-5, lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, membrane tyrosine phosphatase, protein tyrosine phosphatase lambda, protein tyrosine phosphatase receptor type C, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, Protein tyrosine phosphatase, receptor-type, c polypeptide, protein tyrosine phosphatase, alternatively spliced, Ptprc, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen, T220 and B220
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: NFkB p65
Classification: Polyclonal
Concentration: 0.25 mg/mL
Formulation: PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.: Q04206, Q04207
Gene Symbols: RELA
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19697, 5970
Content And Storage: -20°C
Form: Liquid
Applications: ChIP Assay, ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone: __
Conjugate: Unconjugated
Gene: RELA
Gene Alias: avian reticuloendotheliosis viral (v-rel) oncogene homolog A; EBP-1; I79_021812; MGC131774; NF KB; NFkappaB p65; nf-kappa-b p65; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; NF-kappaB transcription factor p65 subunit; NFkB; NF-kB p65 subunit; nfkb rela; NFKB1; nfkb3; NFkB-p50; nuclear factor; nuclear factor kappa b; nuclear factor kappa B subunit p65; nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; p65 NF kappaB; p65 NF-kappa B; p65 NFkB; P65 transcription factor; putative transcription factor p65 homolog; REL A; rel1; rela; RELA proto-oncogene, NF-kB subunit; rela.L; rela-a; Transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel avian reticuloendotheliosis viral oncogene homolog A L homeolog; v-rel reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A (avian); v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65; XELAEV_18022301mg; Xrel1; xrela
Host Species: Rabbit
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate
Product Type: Antibody
Isotype: IgG
Antigen:
NFkB p65
Classification:
Polyclonal
Concentration:
0.25 mg/mL
Formulation:
PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.:
Q04206, Q04207
Gene Symbols:
RELA
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19697, 5970
Content And Storage:
-20°C
Form:
Liquid
Applications:
ChIP Assay, ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone:
__
Conjugate:
Unconjugated
Gene:
RELA
Gene Alias:
avian reticuloendotheliosis viral (v-rel) oncogene homolog A; EBP-1; I79_021812; MGC131774; NF KB; NFkappaB p65; nf-kappa-b p65; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; NF-kappaB transcription factor p65 subunit; NFkB; NF-kB p65 subunit; nfkb rela; NFKB1; nfkb3; NFkB-p50; nuclear factor; nuclear factor kappa b; nuclear factor kappa B subunit p65; nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; p65 NF kappaB; p65 NF-kappa B; p65 NFkB; P65 transcription factor; putative transcription factor p65 homolog; REL A; rel1; rela; RELA proto-oncogene, NF-kB subunit; rela.L; rela-a; Transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel avian reticuloendotheliosis viral oncogene homolog A L homeolog; v-rel reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A (avian); v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65; XELAEV_18022301mg; Xrel1; xrela
Host Species:
Rabbit
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate
Product Type:
Antibody
Isotype:
IgG