53-589-382

KLRG1 Monoclonal Antibody (2F1), Alexa Fluor™ 488, eBioscience™, Invitrogen™

Manufacturer: eBioscience

Select a Size

Pack Size SKU Availability Price
Each of 1 53-589-382-Each-of-1 In Stock ₹ 25,839.12

53-589-382 - Each of 1

₹ 25,839.12

In Stock

Quantity

1

Base Price: ₹ 25,839.12

GST (18%): ₹ 4,651.042

Total Price: ₹ 30,490.162

Antigen

KLRG1

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

O88713

Gene Symbols

Klrg1

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

50928

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

2F1

Conjugate

Alexa Fluor 488

Gene

Klrg1

Gene Alias

2F1; 2F1-Ag; CLEC15A; C-type lectin domain family 15 member A; C-type lectin domain family 15, member A; ITIM-containing receptor MAFA-L; killer cell lectin like receptor G1; killer cell lectin-like receptor subfamily G member 1; killer cell lectin-like receptor subfamily G, member 1; Klrg1; Mafa; MAFA-2F1; MAFAL; MAFA-L; MAFA-LIKE; MAFA-like receptor; Mast cell function-associated antigen; mast cell function-associated antigen (ITIM-containing); mast cell function-associated antigen 2F1; natural killer cell receptor

Host Species

Syrian Hamster

Quantity

100μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

Description

  • Description: This 2F1 monoclonal antibody reacts with the mouse Killer cell Lectin-like Receptor G1 (KLRG1), also known as Mast cell Function-associated Antigen (MAFA)
  • KLRG1 is a homodimer of glycosylated 30-38 kDa subunits and contains a cytoplasmic motif similar to the immunoreceptor tyrosine-based inhibitory motif (ITIM)
  • Rat MAFA was identified as an antigen specific to rat mast cells; however, the expression of mouse KLRG1/MAFA using 2F1 has not been detected on the surface of mouse mast cell lines, bone marrow-derived mast cells, or peritoneal mast cells
  • This antigen is expressed on approximately one-third of mouse NK cells and a subset of T cells
  • MHC class I molecules regulate KLRG1 via interactions with class I-specific inhibitory Ly49 molecules and SHP-1 signaling
  • Although KLRG1 and Ly49 are both lectin-like inhibitory receptors that are regulated by class I MHC expression, the effects of this on cell surface expression of these molecules are opposing, and the underlying regulatory mechanisms distinct
  • Applications Reported: This 2F1 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This 2F1 antibody has been tested by flow cytometric analysis of mouse splenocytes
  • This may be used at less than or equal to 0.25 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • KLRG1 (Killer cell lectin-like receptor G1, MAFA, 2F1-Ag) is a homodimeric member of the lectin-like type 2 transmembrane receptor family whose members contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic domains
  • These ITIMs interact with the SH2 domains of protein phosphatases such as SHP-1
  • KLRG1 is an inhibitory receptor that is expressed on natural killer (NK) cells and certain T cells
  • NK cells are involved in the lysis of tumor cells and virus-infected cells, and mediate humoral and cell-mediated immune responses.

Compare Similar Items

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eBioscience

53-589-382

--


Antigen:
KLRG1

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
O88713

Gene Symbols:
Klrg1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
50928

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
2F1

Conjugate:
Alexa Fluor 488

Gene:
Klrg1

Gene Alias:
2F1; 2F1-Ag; CLEC15A; C-type lectin domain family 15 member A; C-type lectin domain family 15, member A; ITIM-containing receptor MAFA-L; killer cell lectin like receptor G1; killer cell lectin-like receptor subfamily G member 1; killer cell lectin-like receptor subfamily G, member 1; Klrg1; Mafa; MAFA-2F1; MAFAL; MAFA-L; MAFA-LIKE; MAFA-like receptor; Mast cell function-associated antigen; mast cell function-associated antigen (ITIM-containing); mast cell function-associated antigen 2F1; natural killer cell receptor

Host Species:
Syrian Hamster

Quantity:
100μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

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Invitrogen

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Antigen:
Tau

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
P10636

Gene Symbols:
MAPT

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4137

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
HT7

Conjugate:
Alexa Fluor 488

Gene:
MAPT

Gene Alias:
AI413597, AW045860, DDPAC, FLJ31424, FTDP17, FTDP-17, G protein beta1/gamma2 subunit-interacting factor 1, map tau, Mapt, MAPTL, MGC138549, microtubule associated protein tau, microtubule-associated protein tau, microtubule-associated protein tau, isoform 4, microtubules, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, neurofibrillary tangles, Neuronal Marker, paired helical filament-tau, PHFtau, PHF-tau, PPND, PPP1R103, protein phosphatase 1, regulatory subunit 103, pTau, RNPTAU, Tau, Tau microtubule-associated protein, tau protein, Tau-4, Tau5, Unknown (protein for MGC:134287)

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

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Invitrogen

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Antigen:
CD274 (PD-L1, B7-H1)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q9EP73

Gene Symbols:
Cd274

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
60533

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MIH5

Conjugate:
Alexa Fluor 488

Gene:
Cd274

Gene Alias:
A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a λ

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Invitrogen

53-598-342

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Antigen:
CD274 (PD-L1, B7-H1)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
Q9NZQ7

Gene Symbols:
Cd274

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
29126

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MIH1

Conjugate:
Alexa Fluor 488

Gene:
Cd274

Gene Alias:
A530045L16Rik, B7 homolog 1, B7-H, B7h1, B7-H1, Cd274, CD274 antigen, CD274 molecule, PDCD1 ligand 1, Pdcd1l1, Pdcd1lg1, Pdl1, PD-L1, pdl-1, Programmed cell death 1 ligand 1, programmed death ligand 1, RGD1566211, sCD274, soluble CD274, soluble PD L1, sPD L1

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ