53-591-642
Tau Monoclonal Antibody (HT7), Alexa Fluor™ 488, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 53-591-642-Each-of-1 | In Stock | ₹ 35,678.52 |
53-591-642 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,678.52
GST (18%): ₹ 6,422.134
Total Price: ₹ 42,100.654
Antigen
Tau
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.
P10636
Gene Symbols
MAPT
Immunogen
Purified Human Tau protein
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
HT7
Conjugate
Alexa Fluor 488
Gene
MAPT
Gene Alias
AI413597, AW045860, DDPAC, FLJ31424, FTDP17, FTDP-17, G protein beta1/gamma2 subunit-interacting factor 1, map tau, Mapt, MAPTL, MGC138549, microtubule associated protein tau, microtubule-associated protein tau, microtubule-associated protein tau, isoform 4, microtubules, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, neurofibrillary tangles, Neuronal Marker, paired helical filament-tau, PHFtau, PHF-tau, PPND, PPP1R103, protein phosphatase 1, regulatory subunit 103, pTau, RNPTAU, Tau, Tau microtubule-associated protein, tau protein, Tau-4, Tau5, Unknown (protein for MGC:134287)
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4137
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
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Description
- Description: This HT7 monoclonal antibody recognizes human and bovine Tau protein
- The epitope of this antibody has been mapped to residues 159 through 163, corresponding to the amino acid sequence PPGQK of human Tau40
- In certain cell lines and tissue other than brain, clone HT7 may show a low but distinct amount of nonspecific staining
- Therefore we recommend the use of clone HT7 to detect Tau expression by flow cytometry in human Tau transfected cells or tissue derived from human Tau transgenic mice
- This antibody does not cross-react with murine Tau
- Applications Reported: This HT7 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This HT7 antibody has been pre-diluted and tested by flow cytometric analysis of Human Tau transfected 293 HEK cells using the Intracellular Fixation & Permeabilization Buffer Set (Product # 88-8824-00) and protocol
- Please refer to Staining Intracellular Antigens for Flow Cytometry, Protocol A: Two step protocol for intracellular (cytoplasmic) proteins located at www.thermofisher.com/flowprotocols
- This antibody may be used at 5μL (0.25 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser Tau is a neuronal microtubule-associated protein found predominantly on axons
- The function of Tau is to promote tubulin polymerization and stabilize microtubules
- The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both
- Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome
- The short isoforms allow plasticity of the cytoskeleton while the longer isoforms may preferentially play a role in its stabilization
- In its hyper-phosphorylated form, Tau is the major component of paired helical filaments (PHF), the building block of neurofibrillary lesions in Alzheimer's diseases (AD) brain
- Hyper-phosphorylation impairs the microtubule binding function of Tau, resulting in the destabilization of microtubules in AD brains, μgtimately leading to the degeneration of the affected neurons
- Numerous serine/threonine kinases phosphorylate Tau, including GSK-3beta, protein kinase A (PKA), cyclin-dependent kinase 5 (cdk5) and casein kinase II
- Hyper-phosphorylated Tau is found in neurofibrillary lesions in a range and other central nervous system disorders such as Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Compare Similar Items
Show Difference
Antigen: Tau
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: P10636
Gene Symbols: MAPT
Immunogen: Purified Human Tau protein
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: HT7
Conjugate: Alexa Fluor 488
Gene: MAPT
Gene Alias: AI413597, AW045860, DDPAC, FLJ31424, FTDP17, FTDP-17, G protein beta1/gamma2 subunit-interacting factor 1, map tau, Mapt, MAPTL, MGC138549, microtubule associated protein tau, microtubule-associated protein tau, microtubule-associated protein tau, isoform 4, microtubules, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, neurofibrillary tangles, Neuronal Marker, paired helical filament-tau, PHFtau, PHF-tau, PPND, PPP1R103, protein phosphatase 1, regulatory subunit 103, pTau, RNPTAU, Tau, Tau microtubule-associated protein, tau protein, Tau-4, Tau5, Unknown (protein for MGC:134287)
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4137
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Antigen:
Tau
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
P10636
Gene Symbols:
MAPT
Immunogen:
Purified Human Tau protein
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
HT7
Conjugate:
Alexa Fluor 488
Gene:
MAPT
Gene Alias:
AI413597, AW045860, DDPAC, FLJ31424, FTDP17, FTDP-17, G protein beta1/gamma2 subunit-interacting factor 1, map tau, Mapt, MAPTL, MGC138549, microtubule associated protein tau, microtubule-associated protein tau, microtubule-associated protein tau, isoform 4, microtubules, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, neurofibrillary tangles, Neuronal Marker, paired helical filament-tau, PHFtau, PHF-tau, PPND, PPP1R103, protein phosphatase 1, regulatory subunit 103, pTau, RNPTAU, Tau, Tau microtubule-associated protein, tau protein, Tau-4, Tau5, Unknown (protein for MGC:134287)
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4137
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Antigen: CD274 (PD-L1, B7-H1)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9EP73
Gene Symbols: Cd274
Immunogen: __
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a λ
Applications: Flow Cytometry
Clone: MIH5
Conjugate: Alexa Fluor 488
Gene: Cd274
Gene Alias: A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1
Host Species: Rat
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 60533
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Antigen:
CD274 (PD-L1, B7-H1)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9EP73
Gene Symbols:
Cd274
Immunogen:
__
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a λ
Applications:
Flow Cytometry
Clone:
MIH5
Conjugate:
Alexa Fluor 488
Gene:
Cd274
Gene Alias:
A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1
Host Species:
Rat
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
60533
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Antigen: CD274 (PD-L1, B7-H1)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: Q9NZQ7
Gene Symbols: Cd274
Immunogen: __
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: MIH1
Conjugate: Alexa Fluor 488
Gene: Cd274
Gene Alias: A530045L16Rik, B7 homolog 1, B7-H, B7h1, B7-H1, Cd274, CD274 antigen, CD274 molecule, PDCD1 ligand 1, Pdcd1l1, Pdcd1lg1, Pdl1, PD-L1, pdl-1, Programmed cell death 1 ligand 1, programmed death ligand 1, RGD1566211, sCD274, soluble CD274, soluble PD L1, sPD L1
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 29126
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Antigen:
CD274 (PD-L1, B7-H1)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
Q9NZQ7
Gene Symbols:
Cd274
Immunogen:
__
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
MIH1
Conjugate:
Alexa Fluor 488
Gene:
Cd274
Gene Alias:
A530045L16Rik, B7 homolog 1, B7-H, B7h1, B7-H1, Cd274, CD274 antigen, CD274 molecule, PDCD1 ligand 1, Pdcd1l1, Pdcd1lg1, Pdl1, PD-L1, pdl-1, Programmed cell death 1 ligand 1, programmed death ligand 1, RGD1566211, sCD274, soluble CD274, soluble PD L1, sPD L1
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
29126
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Antigen: DDX5
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: P17844
Gene Symbols: DDX5
Immunogen: Purified T antigen-related protein from Ad2+ ND2 virus-infected HeLa cells
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Applications: Flow Cytometry, Immunocytochemistry
Clone: Ab204
Conjugate: Alexa Fluor 488
Gene: DDX5
Gene Alias: 2600009A06Rik, ATP-dependent RNA helicase DDX5, DDX5, ddx5 gene protein, D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 5, DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 5, DEAD (Asp-Glu-Ala-Asp) box helicase 5, DEAD (Asp-Glu-Ala-Asp) box polypeptide 5, DEAD box protein 5, DEAD box RNA helicase DEAD1, DEAD box-5, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5 (RNA helicase, 68kD), DEAD-box helicase 5, DKFZp434E109, DKFZp686J01190, G17P1, HELR, Hlr1, HUMP68, mDEAD1, MGC118083, p68, p68 RNA helicase, PCR product with interspecies-compatible primers, probable ATP-dependent RNA helicase DDX5, RNA helicase p68, RP23-247J12.4
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1655
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Antigen:
DDX5
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
P17844
Gene Symbols:
DDX5
Immunogen:
Purified T antigen-related protein from Ad2+ ND2 virus-infected HeLa cells
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Immunocytochemistry
Clone:
Ab204
Conjugate:
Alexa Fluor 488
Gene:
DDX5
Gene Alias:
2600009A06Rik, ATP-dependent RNA helicase DDX5, DDX5, ddx5 gene protein, D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 5, DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 5, DEAD (Asp-Glu-Ala-Asp) box helicase 5, DEAD (Asp-Glu-Ala-Asp) box polypeptide 5, DEAD box protein 5, DEAD box RNA helicase DEAD1, DEAD box-5, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5 (RNA helicase, 68kD), DEAD-box helicase 5, DKFZp434E109, DKFZp686J01190, G17P1, HELR, Hlr1, HUMP68, mDEAD1, MGC118083, p68, p68 RNA helicase, PCR product with interspecies-compatible primers, probable ATP-dependent RNA helicase DDX5, RNA helicase p68, RP23-247J12.4
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1655
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid