56-932-642
CD326 (EpCAM) Monoclonal Antibody (1B7), Alexa Fluor™ 700, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 56-932-642-Each-of-1 | In Stock | ₹ 28,320.36 |
56-932-642 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 28,320.36
GST (18%): ₹ 5,097.665
Total Price: ₹ 33,418.025
Antigen
CD326 (EpCAM)
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.
P16422
Gene Symbols
EPCAM
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4072
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
1B7
Conjugate
Alexa Fluor 700
Gene
EPCAM
Gene Alias
adenocarcinoma-associated antigen, CD326, cell surface glycoprotein Trop-1, DIAR5, EGP, EGP-2, EGP314, EGP40, EPCAM, Ep-CAM, EpCAM1, epithelial cell adhesion molecule, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, ESA, GA733-2, gp40, hEGP314, HNPCC8, human epithelial glycoprotein-2, KS 1/4 antigen, KS1/4, KSA, Ly74, lymphocyte antigen 74, M1S2, M4S1, major gastrointestinal tumor-associated protein GA733-2, mEGP314, membrane component, chromosome 4, surface marker (35kD glycoprotein), MIC18, MK-1, panepithelial glycoprotein 314, protein 289A, Protein D5.7A, Tacsd1, Tacstd1, TROP1, Trop-1 protein, Tumor-associated calcium signal transducer 1
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: EpCAM (Epithelial cell adhesion molecule, CD326, KSA, TROP1) is a 40 kD cell-surface adhesion molecule participating in homophilic, calcium-independent cell-cell interactions
- EpCAM is a type-I transmembrane protein, and is expressed primarily on the basolateral surface of most epithelia
- Although normal epithelia express low levels of EpCAM, increased expression has been correlated with increased proliferation and progression to a mesenchymal phenotype
- EpCAM has also been used as a diagnostic marker on circulating metastatic carcinoma cells, while cancer cells of non-epithelial origin do not express EpCAM
- Applications Reported: This 1B7 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This 1B7 antibody has been pre-diluted and tested by flow cytometric analysis of A549 cells
- This may be used at 5 μL (0.25 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Alexa Fluor 700 emits at 723 nm and can be excited with the red laser (633-647 nm)
- Most instruments will require a 685 LP mirror and 710/20 band pass filter
- Please make sure that your instrument is capable of detecting this fluorochrome
- Excitation: 633-647 nm; Emission: 723 nm; Laser: Red Laser Ep-CAM (epithelial adhesion molecule, epithelial specific antigen, ESA) is a transmembrane glycoprotein expressed in the epithelium with a molecular weight of approximately 40 kDa, which functions as an epithelial cell adhesion molecule
- Ep-CAM functions as a homotypic calcium-independent cell adhesion molecule, and has a direct impact on cell cycle, proliferation and metabolism of epithelial cells and fibroblasts due to its ability to rapidly induce the proto-oncogene c-myc and the cell cycle regulating genes cyclin A and E
- Ep-CAM mediates Ca2+-independent homotypic interactions
- Formation of Ep-CAM-mediated adhesions have a negative regulatory effect on adhesions mediated by classic cadherins, which may have strong effects on the differentiation and growth of epithelial cells
- Ep-CAM overexpression was suggested to be associated with enhanced epithelial proliferation
- Ep-CAM is highly expressed in human carcinomas, and is a marker for tumors of epithelial lineage
- Ep-CAM is expressed on baso-lateral cell surface in most simple epithelia and many carcinoma types
- Also, Ep-CAM reportedly distinguishes adenocarcinomas from pleural mesotheliomas.
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Show Difference
Antigen: CD326 (EpCAM)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: P16422
Gene Symbols: EPCAM
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4072
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 1B7
Conjugate: Alexa Fluor 700
Gene: EPCAM
Gene Alias: adenocarcinoma-associated antigen, CD326, cell surface glycoprotein Trop-1, DIAR5, EGP, EGP-2, EGP314, EGP40, EPCAM, Ep-CAM, EpCAM1, epithelial cell adhesion molecule, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, ESA, GA733-2, gp40, hEGP314, HNPCC8, human epithelial glycoprotein-2, KS 1/4 antigen, KS1/4, KSA, Ly74, lymphocyte antigen 74, M1S2, M4S1, major gastrointestinal tumor-associated protein GA733-2, mEGP314, membrane component, chromosome 4, surface marker (35kD glycoprotein), MIC18, MK-1, panepithelial glycoprotein 314, protein 289A, Protein D5.7A, Tacsd1, Tacstd1, TROP1, Trop-1 protein, Tumor-associated calcium signal transducer 1
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD326 (EpCAM)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
P16422
Gene Symbols:
EPCAM
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4072
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
1B7
Conjugate:
Alexa Fluor 700
Gene:
EPCAM
Gene Alias:
adenocarcinoma-associated antigen, CD326, cell surface glycoprotein Trop-1, DIAR5, EGP, EGP-2, EGP314, EGP40, EPCAM, Ep-CAM, EpCAM1, epithelial cell adhesion molecule, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, ESA, GA733-2, gp40, hEGP314, HNPCC8, human epithelial glycoprotein-2, KS 1/4 antigen, KS1/4, KSA, Ly74, lymphocyte antigen 74, M1S2, M4S1, major gastrointestinal tumor-associated protein GA733-2, mEGP314, membrane component, chromosome 4, surface marker (35kD glycoprotein), MIC18, MK-1, panepithelial glycoprotein 314, protein 289A, Protein D5.7A, Tacsd1, Tacstd1, TROP1, Trop-1 protein, Tumor-associated calcium signal transducer 1
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: __
Form: __
Applications: __
Clone: __
Conjugate: __
Gene: __
Gene Alias: __
Host Species: __
Quantity: 50 mg
Primary or Secondary: __
Target Species: __
Product Type: __
Isotype: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Gene Symbols:
__
Purification Method:
__
Regulatory Status:
__
Gene ID (Entrez):
__
Content And Storage:
__
Form:
__
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Gene Alias:
__
Host Species:
__
Quantity:
50 mg
Primary or Secondary:
__
Target Species:
__
Product Type:
__
Isotype:
__
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: __
Form: Powder
Applications: __
Clone: __
Conjugate: __
Gene: __
Gene Alias: __
Host Species: __
Quantity: 250 mg
Primary or Secondary: __
Target Species: __
Product Type: __
Isotype: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Gene Symbols:
__
Purification Method:
__
Regulatory Status:
__
Gene ID (Entrez):
__
Content And Storage:
__
Form:
Powder
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Gene Alias:
__
Host Species:
__
Quantity:
250 mg
Primary or Secondary:
__
Target Species:
__
Product Type:
__
Isotype:
__
Antigen: Src (pTyr418)
Classification: Monoclonal
Concentration: __
Formulation: Lyophilized from 2X PBS, PEG, sucrose.
Gene Accession No.: __
Gene Symbols: __
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: −20°C
Form: Purified
Applications: ELISA, Immunoblot, Immunoblot, Immunocytochemistry
Clone: 9A6
Conjugate: Unconjugated
Gene: __
Gene Alias: __
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: __
Isotype: IgG1
Antigen:
Src (pTyr418)
Classification:
Monoclonal
Concentration:
__
Formulation:
Lyophilized from 2X PBS, PEG, sucrose.
Gene Accession No.:
__
Gene Symbols:
__
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
−20°C
Form:
Purified
Applications:
ELISA, Immunoblot, Immunoblot, Immunocytochemistry
Clone:
9A6
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
__
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
__
Isotype:
IgG1